No one best way to measure #infection risk in populations.
Cross-sectional sero: weak temporal signal, CXR, waning as we know. Extra care needed for longitudinal #serology as Ab kinetics and assay noise can mess up estimates by a lot. Cases can be powerful!
www.pnas.org/doi/10.1073/pnas.2411768121
eur03.safelinks.protection.outlook.com
Reconciling heterogeneous dengue virus infection risk estimates from different study designs | PNAS
Uncovering rates at which susceptible individuals become infected with a pathogen,
i.e., the force of infection (FOI), is essential for assessing t...