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Hilda Bastian

@hildabast.bsky.social
11K followers 195 following 676 posts

Scientist (PhD she/her), writer, cartoonist. 🦘 Tracking NextGen Covid Vaccines at vaxtracker.wordpress.com Personal newsletter: Living With Evidence hildabastian.wordpress.com

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Hilda Bastian @hildabast.bsky.social · 02/10/2026
...That 1994 document, The Power of Sharing Knowledge, has been added to the historical collection at the James Lind Library @jameslindlibrary.bsky.social : www.jameslindlibrary.org/bastian-h-19...
jameslindlibrary.org
Bastian H (1994) - The James Lind Library
The report prepared by Hilda Bastian for the UK Cochrane Centre in 1994, about patient and public involvement and engagement in the Cochrane Collaboration.
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Hilda Bastian @hildabast.bsky.social · 02/10/2026
When we started the Cochrane Collaboration—over 30 years ago!—I wrote a proposal for consumer participation in the organization & its work, including setting up a Consumer Network as one of the constituent groups... 1/2
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Hilda Bastian @hildabast.bsky.social · 30/09/2026
I discuss what else is in the pipeline in the paid subscriber section. Now that Moderna's flu vaccine has been approved by the FDA, the door is presumably open to them applying for the combination of 2 approved vaccines. I did look at the monoclonal antibody, but decided it didn't fit.
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Hilda Bastian @hildabast.bsky.social · 29/09/2026
I think a lot of people don't do them together because of that, and then there's the risk of not getting around to the second. I'm very interested to see what happens with the non-mRNA ones—adverse reactions should be a lot lower. (I like the efficiency of a combination vaccine.)
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Hilda Bastian @hildabast.bsky.social · 29/09/2026
....In nextgen Covid vaccines news, there are: —results from a phase 2 trial of a "variant-proof" vaccine —a phase 1/2 clinical trial of a featured vax has fully recruited — 10 preclinical reports vaxtracker.wordpress.com/2026/09/29/t...
vaxtracker.wordpress.com
Flu-Covid combo vax & monthly update of nextgen Covid vax news
Moderna has the first combined flu-Covid vaccine to cross the finish line. An overview of that race plus an update on nextgen Covid vaccine news.
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Hilda Bastian @hildabast.bsky.social · 29/09/2026
My latest nextgen Covid vax update is online: * New feature* Combined flu & Covid vaccines — the first one has been approved for people 50 & over, and a massive effectiveness trial is beginning in Denmark & Spain ... 1/2 vaxtracker.wordpress.com/2026/09/29/t...
vaxtracker.wordpress.com
Flu-Covid combo vax & monthly update of nextgen Covid vax news
Moderna has the first combined flu-Covid vaccine to cross the finish line. An overview of that race plus an update on nextgen Covid vaccine news.
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Hilda Bastian @hildabast.bsky.social · 27/09/2026
PS: I didn't check if the evidence was based on a comparison of the most recent version of each vax.
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Hilda Bastian @hildabast.bsky.social · 27/09/2026
...is here. www.ema.europa.eu/en/documents... As of that time, p 130 conclusion was that it was in several respects superior to Comirnaty as a booster. (I don't know if this applies specifically in your case.) Anyway, plenty to read there at that Agency.
ema.europa.eu
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Hilda Bastian @hildabast.bsky.social · 27/09/2026
That's ok. It's not a nextgen vaccine & I haven't looked at it closely. The original European Medicines Agency assessment was in 2023. More about the vax here:https://www.ema.europa.eu/en/medicines/human/EPAR/bimervax The technical report of their evaluation.... 1/2
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Hilda Bastian @hildabast.bsky.social · 22/09/2026
Thanks! 😊 All the mucosal vaxes aim to reduce infection/transmission:, they'll vary in how much they can. Where they are at depends on where you live (some countries already have one or two). For US/Europe etc, several close to phase 3. My backgrounder: hildabastian.wordpress.com/2024/05/07/w...
hildabastian.wordpress.com
“When Will We Get a Sterilizing Covid Vaccine?”
I get this question a lot. It’s hard to answer in a few words. I know there has been at least one prediction that it could happen this year. I think the question is too complicated for an eas…
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Hilda Bastian @hildabast.bsky.social · 20/09/2026
😊
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Hilda Bastian @hildabast.bsky.social · 17/09/2026
😊
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Hilda Bastian @hildabast.bsky.social · 14/09/2026
It's been five years today since my son Adam died. Missing his smile and his bear hug. Light poem by Robert Montgomery: www.robertmontgomery.org/recycledsunl...
The people you love
become ghosts inside
of you and like this
you keep them alive

Light poem by Robert Montgomery: In neon light on a boardwalk by the sea at twilight.
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Hilda Bastian @hildabast.bsky.social · 09/09/2026
We Still Owe Clinical Trial Participants More Back in 2000, when I was Chairperson of the Consumers' Health Forum of Australia, I chaired the development of a joint National Health and Medical Research Council (NHMRC) and Forum national statement on consumer and community participation in…
hildabastian.wordpress.com
We Still Owe Clinical Trial Participants More
Back in 2000, when I was Chairperson of the Consumers' Health Forum of Australia, I chaired the development of a joint National Health and Medical Research Council (NHMRC) and Forum national statement on consumer and community participation in research. This month I saw that it has recently been revised—the second revision since "our" version was published in 2002. Over 1,100 people attended consultation workshops for this process, and there were more than 200 written submissions.
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Hilda Bastian @hildabast.bsky.social · 30/08/2026
This month's nextgen Covid vax update is packed with news & new features: - Clinical trial reports for 2 vaxes - 2 new trials recruiting, including an open source mRNA vax - 9 preclinical studies .... 1/2 vaxtracker.wordpress.com/2026/08/30/m...
vaxtracker.wordpress.com
This month's next generation Covid vaccine update is packed with news and new features.
Visit the post for more.
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Hilda Bastian @hildabast.bsky.social · 30/08/2026
..A new free feature listing all nextgen Covid vax trials currently recruiting (11 in 6 countries) vaxtracker.wordpress.com/nextgen-covi... Plus a bonus section for the paid subscribers who make this project possible: News, analysis, & debunking — thanks! vaxtracker.wordpress.com/2026/08/30/m...
An anxious coronavirus is thinking, "They're ALL out to get to me!" (Cartoon by Hilda Bastian)
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Hilda Bastian @hildabast.bsky.social · 30/08/2026
This month's nextgen Covid vax update is packed with news & new features: - Clinical trial reports for 2 vaxes - 2 new trials recruiting, including an open source mRNA vax - 9 preclinical studies .... 1/2 vaxtracker.wordpress.com/2026/08/30/m...
vaxtracker.wordpress.com
This month's next generation Covid vaccine update is packed with news and new features.
Visit the post for more.
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Hilda Bastian @hildabast.bsky.social · 19/08/2026
Absolutely Maybe now has another backup archive, at Rogue Scholar: rogue-scholar.org/communities/... Many thanks, @mfenner.bsky.social !
Popart woman's face with purple hair—the original logo for Absolutely Maybe, by Hilda Bastian
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Hilda Bastian @hildabast.bsky.social · 09/08/2026
Herzlichen Dank 😊
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Darren Dahly @statsepi.bsky.social · 04/08/2026
Stop trying to explain what a p-value is in a single sentence (ICYMI) statsepi.substack.com/p/no-you-can...
statsepi.substack.com
No, you can't explain what a p-value is with one sentence (Parts I, II)
But I'm going to try and do it in as few as possible. #fml
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Hilda Bastian @hildabast.bsky.social · 04/08/2026
😊
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Hilda Bastian @hildabast.bsky.social · 04/08/2026
Introducing the NextGen Covid Vax Tracker! vaxtracker.wordpress.com/2026/07/29/i... A monthly update on vaccine progress, featured vaccines, analyses, plus lots of background info. #Vaccines #Covid #Covid19
A happy vaccine (Cartoon by Hilda Bastian)
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Otrosdías @otrosdias.bsky.social · 29/07/2026
Very much recommend subscribing (either free or paid subscription) for up to date analysis of fortcoming next-generation COVId vaccines.
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Lizabeth @life2short16.bsky.social · 29/07/2026
New platform for NextGen Covid Vax Tracker by Hilda Bastian. Free and paid subscription options available
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Hilda Bastian @hildabast.bsky.social · 29/07/2026
Thank you! 😊
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Hilda Bastian @hildabast.bsky.social · 29/07/2026
😊
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Hilda Bastian @hildabast.bsky.social · 29/07/2026
A New Chapter It's wattle time here in country Victoria, and the bees are ecstatic! All that glorious yellow cheers up the middle of winter no end. It's such an optimistic color. I'm feeling optimistic, too, even though this month did not go as planned. That began, as disruptions so often do, with…
hildabastian.wordpress.com
A New Chapter
It's wattle time here in country Victoria, and the bees are ecstatic! All that glorious yellow cheers up the middle of winter no end. It's such an optimistic color. I'm feeling optimistic, too, even though this month did not go as planned. That began, as disruptions so often do, with an unexpected email. This one was from PLOS, the home of my blog, …
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Hilda Bastian @hildabast.bsky.social · 29/07/2026
PLOS' Independent Blog Network is ending this month (2010-2026). I've been so proud to be a longstanding member: Thank you for everything, @plos.org! My farewell post, with thoughts on blogging's history: absolutelymaybe.plos.org/2026/07/29/f...
absolutelymaybe.plos.org
Farewell Post - Absolutely Maybe
Experimenting with colors for the Absolutely Maybe logo feels like another lifetime. It was 2013, and this blog was launching on the…
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Hilda Bastian @hildabast.bsky.social · 29/07/2026
... There are lots of new features at the free-standing Tracker. Subscription to the usual update post is free — with additional new analyses & features for paid supporting subscribers. I hope you'll check it out and spread the word! vaxtracker.wordpress.com
vaxtracker.wordpress.com
Introduction post for the NextGen Covid Vax Tracker
There are dozens of next generation Covid vaccines in clinical trials, with more to come. The Tracker keeps up-to-date with a monthly newsletter on developments in clinical trials and other research.
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Hilda Bastian @hildabast.bsky.social · 29/07/2026
This month, PLOS is shutting down the Independent Blogs Network. I don't want to call it quits on vax tracking though, & hope there's enough interest to keep it going as a reader-supported project. 🤞🤞 Introducing my new & much-improved NextGen Covid Vax Tracker! vaxtracker.wordpress.com 🧵
vaxtracker.wordpress.com
Introduction post for the NextGen Covid Vax Tracker
There are dozens of next generation Covid vaccines in clinical trials, with more to come. The Tracker keeps up-to-date with a monthly newsletter on developments in clinical trials and other research.
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Hilda Bastian @hildabast.bsky.social · 29/07/2026
... Plus Results from 2 Covid human challenge tests — and another one is recruiting. One advanced vax has sadly been shelved. Lots more news, including preclinical studies, now online at PLOS: absolutelymaybe.plos.org/2026/07/29/b... ...2/3
absolutelymaybe.plos.org
Bumper Month of Clinical Trial News to Ring Out This Vax Series - Absolutely Maybe
Before I get to the bumper crop of recent clinical trial news, there is news about this monthly update. This is the…
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Hilda Bastian @hildabast.bsky.social · 29/07/2026
A *bumper* month of nextgen Covid vax clinical trial news: — Results of 2 clinical trials for mucosal vaccines, including Vaxart's oral vax — Another mucosal vaccine is going into clinical trial, and 4 others are fully recruited or completed ...1/3 absolutelymaybe.plos.org/2026/07/29/b...
absolutelymaybe.plos.org
Bumper Month of Clinical Trial News to Ring Out This Vax Series - Absolutely Maybe
Before I get to the bumper crop of recent clinical trial news, there is news about this monthly update. This is the…
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Hilda Bastian @hildabast.bsky.social · 29/06/2026
My monthly update on next generation Covid vaccines is online now @plos.org — with a new streamlined structure I hope makes it easier & quicker to read. News on a major UK grant supporting a UK/US collaboration on a vax from Stanford Uni, plus ...1/2 absolutelymaybe.plos.org/2026/06/29/m...
absolutelymaybe.plos.org
More Trials Recruiting and Other NextGen Covid Vaccine News - Absolutely Maybe
June was a relatively slow news month for next generation Covid vaccine development. So I took the opportunity to simplify the structure…
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Hilda Bastian @hildabast.bsky.social · 29/06/2026
....another 4 trials began recruiting in China, Europe, & USA, and another 2 trials fully recruited in Germany & USA. 6 new preclinical report as well. absolutelymaybe.plos.org/2026/06/29/m...
absolutelymaybe.plos.org
More Trials Recruiting and Other NextGen Covid Vaccine News - Absolutely Maybe
June was a relatively slow news month for next generation Covid vaccine development. So I took the opportunity to simplify the structure…
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Hilda Bastian @hildabast.bsky.social · 29/06/2026
My monthly update on next generation Covid vaccines is online now @plos.org — with a new streamlined structure I hope makes it easier & quicker to read. News on a major UK grant supporting a UK/US collaboration on a vax from Stanford Uni, plus ...1/2 absolutelymaybe.plos.org/2026/06/29/m...
absolutelymaybe.plos.org
More Trials Recruiting and Other NextGen Covid Vaccine News - Absolutely Maybe
June was a relatively slow news month for next generation Covid vaccine development. So I took the opportunity to simplify the structure…
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Hilda Bastian @hildabast.bsky.social · 25/06/2026
An argumentation theorist's ethnographic case study about the Cochrane review on ME/CFS raises, I think, structural implications for journals like Cochrane's. My latest post @plos.org absolutelymaybe.plos.org/2026/06/24/v...
absolutelymaybe.plos.org
Values and Conflicts at Journals - Absolutely Maybe
What makes an argument ‘correct,’ or, at least, reasonable? We can debate about each other’s claims endlessly, and there’s an interdisciplinary field…
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Hilda Bastian @hildabast.bsky.social · 17/06/2026
When Can We Be Sure a Placebo Is Really a Placebo? OK, I admit this cartoon is not on point here. But I think it's one of my better cartoons, and that's my excuse for trotting it out! The point is a recent scoping review on active placebo controls, by David Laursen and colleagues. "Active placebo"…
hildabastian.wordpress.com
When Can We Be Sure a Placebo Is Really a Placebo?
OK, I admit this cartoon is not on point here. But I think it's one of my better cartoons, and that's my excuse for trotting it out! The point is a recent scoping review on active placebo controls, by David Laursen and colleagues. "Active placebo" sounds a bit like a contradiction in terms. That makes using them in trials one of those friction points capitalized in anti-vaccine evidence critiques: If it's active, so the argument goes, it's not a placebo, and the trial's results can be denigrated.
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Hilda Bastian @hildabast.bsky.social · 31/05/2026
A big month for next generation Covid vaccine trials! — Details of an exciting trial in Tanzania for an intranasal vax for low-resource communities—results may come soon; — An overview of the Covid human challenge studies, as one reaches a milestone .... 1/2 absolutelymaybe.plos.org/2026/05/31/a...
absolutelymaybe.plos.org
A Bumper Month of Clinical Trial News (NextGen Covid Vax Update) - Absolutely Maybe
It was a big month for clinical trials of next generation Covid vaccines. An exciting phase 1/2 trial in Africa for an…
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Hilda Bastian @hildabast.bsky.social · 31/05/2026
... — Results from a trial of a pancoronavirus vax, with a 2nd trial for another underway in Europe; —A pancoronavirus vax trial in Australia expands to Sydney; Plus updates on featured vaccines, and 8 preclinical reports Online now @plos.org absolutelymaybe.plos.org/2026/05/31/a...
absolutelymaybe.plos.org
A Bumper Month of Clinical Trial News (NextGen Covid Vax Update) - Absolutely Maybe
It was a big month for clinical trials of next generation Covid vaccines. An exciting phase 1/2 trial in Africa for an…
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Hilda Bastian @hildabast.bsky.social · 31/05/2026
A big month for next generation Covid vaccine trials! — Details of an exciting trial in Tanzania for an intranasal vax for low-resource communities—results may come soon; — An overview of the Covid human challenge studies, as one reaches a milestone .... 1/2 absolutelymaybe.plos.org/2026/05/31/a...
absolutelymaybe.plos.org
A Bumper Month of Clinical Trial News (NextGen Covid Vax Update) - Absolutely Maybe
It was a big month for clinical trials of next generation Covid vaccines. An exciting phase 1/2 trial in Africa for an…
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Hilda Bastian @hildabast.bsky.social · 27/05/2026
Thank you for writing it!
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Reposted by Hilda Bastian
Helen Pearson @helenpearson.bsky.social · 26/05/2026
A bit of medical history to distract from a hot day. My article in @uk.theconversation.com tells a favourite story from BEYOND BELIEF: how a remarkable randomised trial showed conventional wisdom on bedrest was wrong and helped inspire evidence-based medicine. theconversation.com/how-a-remark...
theconversation.com
How a remarkable trial on bedrest during the Korean war helped lead to evidence-based medicine
How a bedbound patient and a 73-page study changed the way doctors make decisions.
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Hilda Bastian @hildabast.bsky.social · 27/05/2026
...Check out free in-person & online events with Helen, too — Today: www.kcl.ac.uk/events/the-f... June 2: www.lse.ac.uk/lse-health/e... June 20: www.lse.ac.uk/events/lse-f...
kcl.ac.uk
The fight for facts: from ‘beyond belief’ to embracing evidence | King's College London
This event will discuss the ‘evidence revolution’ - the global movement that promotes the idea that scientific evidence should guide our decisions rather than unreliable opinions or beliefs – and the ...
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Hilda Bastian @hildabast.bsky.social · 27/05/2026
Fascinating evidence stories galore! @helenpearson.bsky.social's new book is a wonderful read about evidence movements in medicine, social policy, policing, business, & education. Check out my review online now @plos.org absolutelymaybe.plos.org/2026/05/27/b...
absolutelymaybe.plos.org
Beyond Belief: How Evidence Shows What Really Works (Book Review) - Absolutely Maybe
There are several reasons to buy Helen Pearson’s excellent new book, Beyond Belief: How Evidence Shows What Really Works—whether you want to…
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Hilda Bastian @hildabast.bsky.social · 26/05/2026
I don't know enough about what the Foundation being US jurisdiction means in this context.
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Hilda Bastian @hildabast.bsky.social · 26/05/2026
It's where the headquarters is, so I just assume it's where most of the staff is too.
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Hilda Bastian @hildabast.bsky.social · 26/05/2026
PS: By "that this is even needed," I mean public expressions of solidarity, not the union itself of course.
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Hilda Bastian @hildabast.bsky.social · 26/05/2026
I am the 370th Wikipedia editor to sign up declaring solidarity for the Wikimedia staff union: meta.wikimedia.org/wiki/Wiki_Wo... ✊ (Disappointed that this is even needed.)
meta.wikimedia.org
Wiki Workers United - Meta-Wiki
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Hilda Bastian @hildabast.bsky.social · 04/05/2026
They Had Me At “Dog”! "Dog-assisted intervention trials." That phrase was definitely going to make me click! For a brief moment in that odd mind space you're in while scrolling, I wondered how on earth dogs could assist intervention trials (!!). But of course the article was about trials of…
hildabastian.wordpress.com
They Had Me At “Dog”!
"Dog-assisted intervention trials." That phrase was definitely going to make me click! For a brief moment in that odd mind space you're in while scrolling, I wondered how on earth dogs could assist intervention trials (!!). But of course the article was about trials of dog-assisted services—either professionally-delivered therapy with dogs trained to help improve mental health, or activities with untrained dogs.
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Helen Pearson @helenpearson.bsky.social · 28/04/2026
My book BEYOND BELIEF is out today! It says: in a world flooded with questionable claims and misinformation, evidence from science can help show what’s nonsense – and what’s not. In other words: "Essential reading for the rational-minded". Please repost! 1/🧵 @princetonupress.bsky.social
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