Reposted by Chandra Krishnan, MD
After the diagnosis of EAS, it was sent out for Foundation One. They found EWSR1::NFATC2, and this is a superb example of this novel, distinctive osseous vascular neoplasm. They seem to have potential to recur locally and there is a report of a metastatic one. Nice paper by a former fellow
pubmed.ncbi.nlm.nih.gov
Vascular Neoplasms With NFATC1/C2 Gene Alterations : Expanding the Clinicopathologic and Molecular Characteristics of a Distinct Entity - PubMed
Despite significant advances in their molecular pathogenesis, skeletal vascular tumors remain diagnostically challenging due to their aggressive radiologic appearance and significant morphologic overl...
