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Hellen C. Greenblatt

@hellengreenblat.bsky.social

851 followers 2.5K following 133 posts

#Homeostasis is essential. Interests in #gut-#brain-#immune axis. #Microbiome. Balance and limit #inflammation → ↑ QOL.

Hellen C. Greenblatt @hellengreenblat.bsky.social · 22/07/2026

60% #Sjögren's ↑ #interferon alpha +absence of TRIM21( cytoplasmic protein with ligase activity Increase seen decades before diagnosis.Two different types of Sjögren's syndrome. l1nq.com/c7dfv5i l1nq.com/1fb09tx

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 31/03/2026

Mediterranean diet, #probiotics, and #fecal microbiota transplantation → #gut–brain axis → ↆ #neuroinflammation→ ↑ #cognition, #memory and executive function. bit.ly/4m02VYf [open access] bit.ly/3Qasn15

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 17/03/2026

#Inflammation from gut #mcirobiome affects brain signaling via the #vagus nerve, linking gut health to #cognition. Altering composition can reverse cognitive decline in aging mice, enhancing memory formation. stanford.io/4rysCQz go.nature.com/4sPbw1W [open access].

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 13/03/2026

People with chronic #pain → ↑ developing hypertension, partly explained by #inflammation and #depression. bit.ly/4lppLYK bit.ly/3P4n9DO

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 19/02/2026

When attacked by the same virus, individuals produce #antibodies that target different parts of that virus. For a given #virus, some antibodies increase with #age while others decrease, depending on the viral fragment targeted. bit.ly/40kYPzG bit.ly/4rlralr [open access]

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 15/02/2026

In older individuals, ↑ #inflammation and lower levels of #antioxidant assoc. w poorer #sleep. [open access] bit.ly/4cvAxKA bit.ly/4aI3kJI

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 11/12/2025

Vividly imagining a positive interaction with someone can increase how much you like them — and alter how your brain stores information about that person. (Similar to those seen when people learn from real rewarding experiences.) bit.ly/4ac9dAe go.nature.com/48SDuS9 [open access]

The neural basis of endogenous reinforcement learning.

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 14/10/2025

In vivo, maternal Ig ↆ oral #rotavirus vaccine immunogenicity by ↑ vaccine clearance, thereby ↆ protection. Note: in mice, MatAb interference is mediated by milk-derived antibodies. In humans, transplacental versus breast milk antibodies likely depends on the vaccine platform. bit.ly/3L8thbU

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 01/09/2025

#Parkinson’s disease. 5/10 of PD brains evidence of human #pegivirus (HPgV) vs. 0/14 HPgV-. HPgV-brain+ patients with PD → ↑ neuropathology. Blood+ →↑ IGF-1 and ↆ pS65-ubiquitin, supporting disruption in #mitophagy in response to #HPgV. bit.ly/4mEAuOT [open access].

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 22/08/2025

#Mesenchymal stromal cells (MSCs) → mediate repair. #Obesity impairs MSC functionality → #inflammation. bit.ly/4mEqzZJ

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 18/06/2025

Pro-inflammatory signaling in #adipocytes essential for adipose expansion, remodeling, and tissue integrity. Counterintuitive? Suppression of adipocyte #inflammation →tumor-friendly microenvironment →mammary #cancer progression. bit.ly/4k7kKCc

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 25/12/2024

#Circadian clock rhythm is driven by #mitochondria→ #inflammation.” … new therapies targeting inflammasomes could be more effective if administered at specific times of the day when macrophage activity peaks.” bit.ly/4j6mexh bit.ly/3BLB4Z2 [open access]

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 17/12/2024

BALANCING ACT “#Inflammation is both our body’s best natural defense and the underlying cause of many serious, chronic illnesses. How do you treat a dangerous condition that’s also a fundamental biological process?” bit.ly/41CuTRp [open access]

Cover of the Rockefeller Institute's publication SEEK depicting a woman on a tightrope with immune cells around her.

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Hellen C. Greenblatt @hellengreenblat.bsky.social · 27/11/2024

#Mitochondria triggers #inflammation by halting apoptosis. bit.ly/3CN9v1I bit.ly/3COKW4v

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