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Heidi Pak, Ph.D.

@heidipak.bsky.social
334 followers 811 following 2 posts

🕘 Welch Foundation LSRF Postdoctoral Fellow in Joseph Takahashi’s Lab at UT Southwestern. 👵🏼 PhD from Dudley Lamming’s Lab at the University of Wisconsin-Madison. Interested in the impact of feeding and fasting on aging and circadian rhythms.

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Reposted by Heidi Pak, Ph.D.
Lamming Lab @lamminglab.bsky.social · 27/11/2024
Pleased to announce the publication of our new manuscript, "Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging" in Nature Aging today! www.nature.com/articles/s43... Free link: rdcu.be/d1DGk
nature.com
Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging - Nature Aging
Yeh et al. explore the effects of restricting dietary protein, or isoleucine specifically, in aged mice. They uncover benefits to metabolic health and certain indicators of aging and a sexually dimorp...
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Heidi Pak, Ph.D. @heidipak.bsky.social · 20/11/2024
It depends on the question! I recommend having a minimum of two time-points as metabolite levels seem to be rhythmic. Please check out my paper, figure 4 as an example www.cell.com/cell-reports...
cell.com
Non-canonical metabolic and molecular effects of calorie restriction are revealed by varying temporal conditions
Pak et al. find that many canonical effects of calorie restriction, including insulin sensitivity, result from the specific temporal conditions chosen. Feeding time, fasting duration, and the time of ...
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Heidi Pak, Ph.D. @heidipak.bsky.social · 19/11/2024
Happy to restart my science network here. Please add me if you are a metabolism, aging, feeding behavior, and circadian rhythms enthusiast!
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