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Reposted by Hélène Calais

Giulia Bertolin @bertolingiulia.bsky.social · 02/06/2026

🔬✨ New paper alert! advanced.onlinelibrary.wiley.com/doi/10.1002/... We show kinase activation and mitochondrial bioenergetics at the nanoscale by combining FRET + super-resolution microscopy. 💡 Want to try it? Our method and code is 100% open-source. DM me if you’re interested!

advanced.onlinelibrary.wiley.com

Combining Fret and Super‐Resolution Microscopy Reveals Kinase Activation and Mitochondrial Activity at the Nanoscale

BioSenSRRF is an open-source workflow that combines conventional FRET biosensors with SRRF reconstruction to generate sub-diffraction FRET index maps on standard microscopes. The pipeline integrates ...

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Hélène Calais @hecalais.bsky.social · 08/12/2025

Excited to share that our review "Stress at the gates: Mitochondrial import dysfunctions, response pathways, and therapeutic potential" is now online! 📄 ✨ Huge thanks to my PhD supervisor, @bertolingiulia.bsky.social, for her constant support during the writing process. Hope you'll enjoy it! ✨

sciencedirect.com

Stress at the gates: Mitochondrial import dysfunctions, response pathways, and therapeutic potential

Mitochondrial protein import is necessary to ensure the proper functioning of the organelle of the cell as a whole. More than 1000 proteins are synthe…

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Reposted by Hélène Calais

GdR ImaBio 🔬 @gdrimabio.bsky.social · 20/10/2025

#Mifobio2025 - You came home exhausted, but admit it, you already miss #Mifobio 😉 👉 Report by @france3-naquitaine.bsky.social on the @cnrs.fr thematic school organised for 22 years by the #GDRImabio : youtu.be/qDfPJiDmAsM @cnrsbiologie.bsky.social @cnrsingenierie.bsky.social

youtu.be

MIFOBIO 2025 - Reportage FRANCE 3 Nouvelle Aquitaine

YouTube video by GDR Imabio - CNRS

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Reposted by Hélène Calais

Giulia Bertolin @bertolingiulia.bsky.social · 13/10/2025

Excited to share our #BioSenSRRF preprint on bioRxiv! 🎉 We show how SRRF microscopy can be used with FRET-based biosensors to 🔬mitochondrial functions with high resolution 😍. Code and test data are open (GitHub + Zenodo). 👏 to Nicolas, Pierre-Jean, and co-authors! www.biorxiv.org/content/10.1...

biorxiv.org

Combining FRET and super-resolution microscopy reveals kinase activation and mitochondrial activity at the nanoscale

Protein kinases are key regulators of intracellular signaling, showing activities in specific subcellular compartments and in micro- or nano-domains. Genetically encoded biosensors based on Förster′s ...

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