Reposted by Patricija van Oosten-Hawle, PhD
Our latest work on the ever-fascinating skn-1 transcription factor (Nrf1 and Nrf2 for non-worm people).
www.biorxiv.org/content/10.1...
biorxiv.org
Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2
The Nrf/NFE2L family of transcription factors regulates redox balance, xenobiotic detoxification, metabolism, proteostasis, and aging. Nrf1/NFE2L1 is primarily responsible for stress-responsive upregu...
