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Reposted by Heather Hartmann

Matthew Loberg @maloberg.bsky.social · 06/02/2025

We are excited to share our recent pre-print exploring cancer-associated fibroblast (CAF) phenotypes as thyroid cancers progress from treatable well-differentiated tumors to highly lethal anaplastic thyroid cancer! @vivianweiss.bsky.social @hartheat.bsky.social www.biorxiv.org/content/10.1...

biorxiv.org

An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulations

Thyroid cancer progression from curable well-differentiated thyroid carcinoma to highly lethal anaplastic thyroid carcinoma is distinguished by tumor cell de-differentiation and recruitment of a robus...

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