#RNA is more than genetic material; it can be a community defense factor. Our new publication shows that extracellular RNA released during bacterial cell death can bind and sequester cationic antibiotics, reducing their uptake in neighboring cells. #Antibiotics
www.nature.com/articles/s42...
nature.com
Extracellular RNA confers tolerance to cationic antibiotics by sequestering them - Communications Biology
Lysis-released eRNA sequesters cationic antibiotics, reducing drug uptake by neighboring bacteria and promoting community-level tolerance. This extracellular buffering mechanism reveals how dying cell...