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Niles Donegan

@happypig.bsky.social
399 followers 1.1K following 293 posts

Microbiologist working on Cas12-mediated viral genome editing at the VA Medical Center in WRJ, Vermont. NH based. Big (Red & Green). "Practice every day has made Pangur perfect in his trade; I get wisdom day and night, Turning darkness into light."

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Niles Donegan @happypig.bsky.social · 05/10/2026
Voon (Something mattresses say when they are emotionally moved by something, in both a positive and negative manner.)
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Niles Donegan @happypig.bsky.social · 03/10/2026
Who willingly chooses this hairstyle unless it’s what you are stuck with because you have gum stuck in it?
Riley Moore and his … hair.
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Niles Donegan @happypig.bsky.social · 03/10/2026
I’ve a tabby that parked it in a similar way.
A tabby cat half sitting on a stepA tabby cat half sitting on a step
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Niles Donegan @happypig.bsky.social · 02/10/2026
There are old mushroom hunters. There are bold mushroom hunters. But there are no old and bold mushroom hunters.
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Niles Donegan @happypig.bsky.social · 02/10/2026
From the Frantics “Ti Kwan Leep” skit: Master: No, no, we have not even begun upon the path. Ed Gruberman, you must learn patience Ed Gruberman: Yeah, yeah, yeah, patience. How long will that take? youtu.be/ajEOZ4tBqjQ?...
youtu.be
The Frantics - Ti Kwan Leep -- Boot To The Head
YouTube video by Thomas Nicolai
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Reposted by Niles Donegan
McSweeney's @mcsweeneys.net · 01/10/2026
"The class is ideally a prerequisite to committing sexual assault. This empowers students to take responsibility and get ahead of their punishments on their schedules rather than at inopportune times, should they, say, rape a peer just before finals." buff.ly/5na4oMY
buff.ly
Announcing Cornell University’s Newest Writing Course: Rape Essays 101
“Can a rapist’s prose effectively elicit remorse for sexual assault? What word count best equates to appropriate jail time? In this class, we will dissect wh...
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Niles Donegan @happypig.bsky.social · 30/09/2026
“Any suggestion that the University did not impose consequential punishments for those involved is false," Cornell said” I hope they also run the “I’m sorry” essays that were imposed through Pangram.
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Niles Donegan @happypig.bsky.social · 25/09/2026
Alums and high school seniors are the main posters on r/Dartmouth. All the undergrads are on Fizz.
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Niles Donegan @happypig.bsky.social · 22/09/2026
The chewing louse Strigiphilus garylarsoni is a darn good name though. en.wikipedia.org/wiki/Strigip...
en.wikipedia.org
Strigiphilus garylarsoni - Wikipedia
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Niles Donegan @happypig.bsky.social · 21/09/2026
What slide number in the pdf is it? I can’t find it.
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Niles Donegan @happypig.bsky.social · 17/09/2026
What are the range and units for the Y-axis? It’s impossible to evaluate without them.
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Niles Donegan @happypig.bsky.social · 15/09/2026
FYI firewood banks exist alongside food pantries. newrepublic.com/article/2040...
newrepublic.com
Firewood Banks Aren’t Inspiring. They’re a Sign of Collapse.
Rural communities are banding together to chop firewood so that people in need can heat their homes. This shouldn’t be necessary.
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Niles Donegan @happypig.bsky.social · 12/09/2026
All gels were “washed 10 times with water, for 20 min per wash”. Wowzers.
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Niles Donegan @happypig.bsky.social · 11/09/2026
Except that F’ing AIM/CD5L mutation that causes 2/3 of them to have their kidneys to fall apart and die from CKD. The gene therapy from the Miyazaki group can’t come fast enough.
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Niles Donegan @happypig.bsky.social · 03/09/2026
Time for Dartmouth to get rid of the Black Family Visual Arts Center name.
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Niles Donegan @happypig.bsky.social · 02/09/2026
Bit more local take than the WSJ. vtdigger.org/2026/08/28/b...
vtdigger.org
Ben & Jerry’s legacy hits bumpy patch with latest turn in corporate saga - VTDigger
“This is about the heart and soul of Ben & Jerry's,” said co-founder Ben Cohen, and “whether it will continue to take stands that not everybody agrees with.”
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Niles Donegan @happypig.bsky.social · 31/08/2026
Me too
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Niles Donegan @happypig.bsky.social · 29/08/2026
store.mcsweeneys.net/products/obe...
store.mcsweeneys.net
Obey in Advance: How to Survive (and Thrive) Under Authoritarianism
This is a preorder. Obey in Advance will be released in September of this year, with copies shipping prior to release. get 20% off when you purchase the book alongside the official Obey in Advance hat...
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Niles Donegan @happypig.bsky.social · 28/08/2026
"The latest approval score represents the lowest popularity rating given any President in 20 years. The Gallup Poll's final report on President Truman's popularity, in January 1953, showed the same percentage of Americans, 31 percent, expressing approval." (Same ref)
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Niles Donegan @happypig.bsky.social · 28/08/2026
“3 in 10 Americans (31 percent) say they approve of the way Mr. Nixon is handling his job as President, a drop of 9 points over the last four weeks and an over drop of 37 since his high point in January following the Vietnam peace settlement.” George Gallup, The Boston Globe, 8/15/1973. A25.
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Niles Donegan @happypig.bsky.social · 23/08/2026
This is reminiscent of the educational pods that the libertarians in Croydon NH were looking to put in after they gutted the local school budget.
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Niles Donegan @happypig.bsky.social · 20/08/2026
“Only 3 in 10 Americans (31 percent) say they approve of the way Mr. Nixon is handling his job as President, a drop of 9 points over the last four weeks and an over drop of 37 since his high point in January following the Vietnam peace settlement.” George Gallup, The Boston Globe, 8/15/1973. A25.
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Niles Donegan @happypig.bsky.social · 19/08/2026
Moxie and milk was how my grandmother in central Mass introduced the stuff to me. Still a great mix.
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Niles Donegan @happypig.bsky.social · 17/08/2026
"The latest approval score represents the lowest popularity rating given any President in 20 years. The Gallup Poll's final report on President Truman's popularity, in January 1953, showed the same percentage of Americans, 31 percent, expressing approval." (Same ref)
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Niles Donegan @happypig.bsky.social · 17/08/2026
“Only 3 in 10 Americans (31 percent) say they approve of the way Mr. Nixon is handling his job as President, a drop of 9 points over the last four weeks and an over drop of 37 since his high point in January following the Vietnam peace settlement.” George Gallup, The Boston Globe, 8/15/1973. A25.
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Niles Donegan @happypig.bsky.social · 09/08/2026
I think the combination of the libertarian vibe in “A Moon is a Harsh Mistress” and the story’s mass driving of rocks at Earth is a fun fantasy world for the people making these arguments.
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Niles Donegan @happypig.bsky.social · 08/08/2026
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Niles Donegan @happypig.bsky.social · 01/08/2026
Share and enjoy!
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Niles Donegan @happypig.bsky.social · 31/07/2026
Tom Weller’s incredible book “Science Made Stupid” (1985)
Tom Weller’s incredible book “Science Made Stupid” (1985)
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Niles Donegan @happypig.bsky.social · 30/07/2026
The shutdown of the Vermont Yankee reactor really stands out.
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Niles Donegan @happypig.bsky.social · 22/07/2026
If truth-in-labeling laws were ever enforced:
Tom Weller’s incredible book “Science Made Stupid” (1985)
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Niles Donegan @happypig.bsky.social · 21/07/2026
“But i neeeed the chopper because i now l live so far away”
union-bulletin.com
JD Vance demanded military helicopter transport for son’s golf lesson: report
A bombshell new report reveals that Secret Service agents assigned to JD Vance and his family have become increasingly frustrated about the vice president and his office pressing them for
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Niles Donegan @happypig.bsky.social · 21/07/2026
This was decided by two Trump-appointed judges and one from Dubya.
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Niles Donegan @happypig.bsky.social · 19/07/2026
Love it! The Goodsell Ridge Fossil Preserve in Isle La Motte also has an incredible deep time walk where you can see (and touch) fossils from 480 million years ago. The one down side was there were Patriot Front stickers and pamphlets littering the area. May they be only fossils too one day.
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Niles Donegan @happypig.bsky.social · 17/07/2026
🏅Dad 🏅
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Niles Donegan @happypig.bsky.social · 17/07/2026
Leather goddesses of Phobos for a nine year old 😳
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Niles Donegan @happypig.bsky.social · 16/07/2026
Could you make a trip to Biddeford? Presence of reps make a difference. It’s not far from NH.
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Niles Donegan @happypig.bsky.social · 14/07/2026
Seems on-point
static.klipy.com
Lego Movie Kragle
Alt: Lego Movie Kragle
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Niles Donegan @happypig.bsky.social · 06/07/2026
And the Lyman property is now on a private road after his lawyers petitioned the selectboard. It’s also in current use, which reduces his tax exposure by $10k a year.
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Niles Donegan @happypig.bsky.social · 06/07/2026
Bizarre that his Rosita Returns LLC that he owns the Lyman house through is named after his childhood dog that he had exhumed from his Philadelphia yard where he grew up.
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Niles Donegan @happypig.bsky.social · 01/07/2026
This was 5-4. One vote. Please say whether or not you would support a bill expanding the SCOTUS in 2029 following a Democratic victory. If no, you are useless to restoring democracy to America and deserve to be primaried by somone who will vote that way.
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Niles Donegan @happypig.bsky.social · 28/06/2026
Being able to hear “Way down yonder in the minor key” live? Must have been incredible.
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Niles Donegan @happypig.bsky.social · 27/06/2026
So tone deaf to the 90s. en.wikipedia.org/wiki/Contrac...
en.wikipedia.org
Contract with America - Wikipedia
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Niles Donegan @happypig.bsky.social · 27/06/2026
Love it. Thank you for asking us to notice SEPs again.
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Niles Donegan @happypig.bsky.social · 27/06/2026
Sadly, Luke Farritor, one of the brilliant young minds that deciphered the first word (porphyras) from the scrolls and thus won a major stage of the Vesiuvius Challenge, then did a hard pivot to DOGE and was one of the main maniacs tearing down the government. en.wikipedia.org/wiki/Luke_Fa...
en.wikipedia.org
Luke Farritor - Wikipedia
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Niles Donegan @happypig.bsky.social · 27/06/2026
I’m incredibly disappointed that you are setting up the classic Democratic circular firing squad. I’m a NH-02 voter and I’ll make sure everyone in my region knows that you think the DSA is more a threat than GOP.
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Niles Donegan @happypig.bsky.social · 24/06/2026
static.klipy.com
Hold Fast Pirate Tattoo
Alt: Hold Fast Pirate Tattoo
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Niles Donegan @happypig.bsky.social · 20/06/2026
White US flag yet VA employees were told by the VA secretary not to use (and in fact report) any US flag variant on a VA campus.
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Niles Donegan @happypig.bsky.social · 20/06/2026
I wish they’d rationalize a megadose of an AAV-based therapeutic from some n=1 observation, so that when they injected 10^18 vg/ml, all their livers would melt. Maybe someone can gin up that paper and push it through a predatory, non-peer reviewed journal. This is the type of science they want.
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Niles Donegan @happypig.bsky.social · 11/06/2026
Mark where he’s buried and decorate it appropriately for all the years to come.
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