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Hannah Stacey

@hannahdstacey.bsky.social
55 followers 83 following 1 posts

Postdoc at the La Jolla Institute for Immunology | Studying mucosal immunology, influenza vaccines, antibody responses and B cells | PhD from McMaster University

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Reposted by Hannah Stacey
Prof. Shane Crotty @profshanecrotty.bsky.social · 30/07/2025
After 30+ years of HIV vaccine clinical trials, this is the first time that neutralizing antibodies against an HIV clinical isolate has been generated in vaccinated people. * "Tier 2" neutralizing antibodies, induced consistently. www.science.org/doi/10.1126/... www.science.org/doi/10.1126/...
science.org
Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models
An HIV envelope trimer mRNA vaccine enables membrane-bound expression and produces a functional immunogen in preclinical mammalian models.
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Hannah Stacey @hannahdstacey.bsky.social · 22/07/2025
🚨 New preprint! We show that intranasal FluMist vaccination induces local HA-specific memory B cell responses in the upper airway, even in the absence of strong systemic responses. Investigating local immunity will be key to designing improved vaccines for respiratory pathogens.
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