By mapping brain activity like a moving weather system, researchers found that psychedelics consistently reduce the upward flow of sensory information into higher-order brain regions, offering new bio...

Explore race and ethnicity across the United States with interactive dots, hexagons and clusters from the 2020 Census. By Kyle Walker.

Networks of bioelectronic sensors and actuators enable closed-loop therapies that connect distant, related physiological dynamics. Currently, device interactions are limited by communication methods t...

Linked Discoveries is an experimental tool to help scientists see how individual research findings relate to the larger body of biomedical evidence.

The best way to discover and share scientific posters.

Scientists using the upgraded Advanced Photon Source discovered a new material with a record-setting thermal conductivity.

Even without hitting the gym, older adults taking daily creatine saw increases in muscle mass and memory performance, highlighting the supplement's potential anti-aging benefits.

This JAMA Patient Page describes the psychedelic compound psilocybin, its medical and recreational use, and its potential side effects.

A longitudinal study reveals that playing fast-paced action games and turn-based strategy games can enhance memory and attention. Brain scans indicate that action games lead to stronger and longer-las...

ChatGPT and other AIs use a flood of facts, and the occasional lie, to persuade humans

Hashimoto et al. show that CD4 CTLs expand around age 100 and form large private clones without exhaustion. These cells exhibit stepwise differentiation and cytokine plasticity, suggesting adaptive re...

Zhu et al. develop a scalable, feeder-free platform to generate allogeneic NY-ESO-1-specific T (AlloESO-T) cells from human HSPCs. These mono-specific, cytotoxic T cells combine TCR-driven antigen spe...

Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling, often irreversible toxicity that affects millions of patients, limits life-saving cancer therapy, and lacks proven treatment. In this ...

Recent discoveries have revealed that breast cancer cells are more flexible than previously thought. Some can change from a differentiated state, when a mature cell has taken on a specific function, b...

New research in mice shows that stimulating the vagus nerve after training enhances long-term learning. The stimulation also triggers rhythmic changes in brain blood flow, suggesting learning depends ...

Acoustic and elastic metamaterials enable unprecedented wave control but rarely reach real-world device applications. Here, authors co-integrate dual-domain metamaterials with a piezoelectric ultrason...

Researchers use tightly focused laser beams to image biological samples, shape materials with microscopic precision and generate displays. But using those beams in three dimensions requires more than ...

Molecular Psychiatry - Empirical evidence for gut microbial influence on human brain neurochemistry via the gut–brain axis

The circadian clock maintains synchrony between biological processes and light/dark cycles by integrating environmental cues. How the clock adapts to seasonal variations in the environment is incomple...

mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.

Functionally stable regulatory T cells converted in vitro from pathogenic T cells can confer antigen-specific immunosuppression in pemphigus vulgaris.

Autonomic dysreflexia can be reversed using epidural electrical neuromodulation

Precise adjustment of the doping level in a transition metal dichalcogenide heterostructure using electrostatic gating demonstrates a wide range of tunability in the exciton oscillator strength and th...

Thunder generates atmospheric acoustic waves that couple into the ground, producing seismic signals called “thunderquakes.” Although widely observed, this atmosphere-solid Earth conversion has rarely ...

Mizrachi et al. show that directing attention to bodily sensations, rather than away, promotes more regulated acute inflammatory responses in healthy volunteers, revealing sensory and vagal pathways l...

DCCBs were associated with increased kidney disease progression in Type 2 diabetes patients receiving standard care. Find out more.

Objectives To characterise the non-linear joint dose–response relationship of accelerometer-measured moderate-to-vigorous physical activity (MVPA) and cardiorespiratory fitness (CRF, estimated as maxi...

Previous brain-wide association studies (BWAS) have linked specific environmental and behavioral variables to brain variability. In this work, we mapped 649 variables to children’s brains and compared...

Microrobots made of human-induced pluripotent stem cells and magnetoelectric nanoparticles promote lesion repair and motor improvements after spinal cord injury in zebrafish and mice under magnetic gu...

Abstract. Due to the emergence of resistance to both artemisinin derivatives, and their partner drugs, new antimalarials are urgently needed. Ideally, new

Abstract. Polymer-derived ceramics (PDCs) are promising candidates for fabricating three-dimensional (3D) micro/nanodevices. However, their advancement has

The result is a simple and efficient neuromorphic device that mimics a brain cell

A self-regulated photothermal superhydrophobic film with strong solar modulation, energy storage, and durability is reported, switching between black and white as temperature changes, enabling winter ...

New machine may solve optimization problems that are too hard for regular computers

Through spatial multiomics, spatial stable isotope tracing and retrospective cohort analyses, this study identifies hyperglycosylation as a driver of Alzheimer’s disease and a promising therapeutic ta...

BackgroundAdvanced Alzheimer’s disease (AD) is generally regarded as a stage of irreversible functional decline. Psilocybin is known to transiently alter lar...

Researchers at National Jewish Health have uncovered a previously unknown mechanism that helps drive inflammation in allergic asthma, offering new insight into how the disease develops and potentially...

Hidden pathways governing oxygen transfer and reactions inside wine bottles are revealed across multiple timescales.