Starting 2025 the right way ! Very delighted to share our work describing how hypoxia decreases MHC I expression and the immunopeptidome leading to immune evasion. A huge thank you to our collaborators and all the contributing authors! www.embopress.org/doi/full/10....
embopress.org
Hypoxia promotes tumor immune evasion by suppressing MHC-I expression and antigen presentation | The EMBO Journal
imageimageHypoxia contributes to cancer resistance to both standard therapies and immunotherapy.
This work demonstrates that tumor hypoxia promotes immune evasion by autophagy-mediated
downregulation ...
