Brian Krueger, PhD @h2so4hurts.bsky.social · 05/08/2025@whysharksmatter.bsky.social Thoughts? www.youtube.com/watch?v=VdGb...youtube.comShark Dentist - Official Announcement TrailerYouTube video by IGN 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 15/07/2025DNA is coded by 4 bases, but no one said that's how we have to sequence it. Ready to have your mind bent? 🧬 🧪omic.lyFuzzy Sequencing: Sometimes close enough is good enoughDNA is coded by 4 bases, but no one said that's how we have to sequence it. Ready to have your mind bent? 0110
Brian Krueger, PhD @h2so4hurts.bsky.social · 20/05/2025Having trouble sleeping? A new mutation has been discovered that allows people to feel well rested after as little as 4hrs of sleep! 🧬 🧪 www.omic.ly/a-gene-for-s...omic.lyA gene for short sleep durationHaving trouble sleeping? A new mutation has been discovered that allows people to feel well rested after as little as 4hrs of sleep! 1122
Brian Krueger, PhD @h2so4hurts.bsky.social · 17/05/2025So you're cherry picking out all the parts of a post about Rosalind Franklin and her life that don't mention Rosalind Franklin and her life? Cool. 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 17/05/2025The most famous photo in the history of genetics wasn’t generated by Watson and Crick, but that didn’t stop them from using it to solve the structure of DNA. 🧬 🧪 #histSci www.omic.ly/the-most-fam...omic.lyThe most famous picture in the history of geneticsThe most famous photo in the history of genetics wasn’t generated by Watson and Crick, but that didn’t stop them from using it to solve the structure of DNA. 2225
Brian Krueger, PhD @h2so4hurts.bsky.social · 15/05/2025Mass Spec is leading the charge in bringing high-throughput proteomics to a lab near you. 🧬 🧪 www.omic.ly/mass-spec-is...omic.lyMass spec is primed to lead the next proteomics revolutionMass Spec is leading the charge in bringing high-throughput proteomics to a lab near you. 082
Brian Krueger, PhD @h2so4hurts.bsky.social · 13/05/2025There’s more to de novo mutations (DNMs) than just SNPs and indels. 🧬 🧪 www.omic.ly/de-novo-muta...omic.lyDe novo mutations are more common than we previously thoughtThere’s more to de novo mutations (DNMs) than just SNPs and indels. 030
Brian Krueger, PhD @h2so4hurts.bsky.social · 01/05/2025Multiplex aptamer/antibody arrays are a gateway drug to get genetics people to embrace proteomics. 🧬 🧪 www.omic.ly/how-to-do-pr...omic.lyHow to do proteomics using a high throughput sequencerMultiplex aptamer/antibody arrays are a gateway drug to get genetics people to embrace proteomics. 072
Brian Krueger, PhD @h2so4hurts.bsky.social · 29/04/2025Approximately 2,000 people die every year waiting for a liver transplant. Pigs might help change that! 🧬 🧪 www.omic.ly/a-pig-liver-...omic.lyA pig liver makes its way into a humanApproximately 2,000 people die every year waiting for a liver transplant. Pigs might help change that! 2101
Brian Krueger, PhD @h2so4hurts.bsky.social · 24/04/2025High throughput proteomics could revolutionize our understanding of human disease, but it's going to take some major innovations to get us there! 🧬 🧪 www.omic.ly/the-future-o...omic.lyThe future of high throughput proteomics is unfolding right in front of usHigh throughput proteomics could revolutionize our understanding of human disease, but it's going to take some major innovations to get us there! 171
Brian Krueger, PhD @h2so4hurts.bsky.social · 22/04/2025Ultima Genomics is put to the test in MRD 🧬 🧪 www.omic.ly/will-ultimas...omic.lyWill Ultima's ultra cheap bases be a major boon to MRD?Ultima Genomics is put to the test in MRD 030
Brian Krueger, PhD @h2so4hurts.bsky.social · 21/04/2025Derek Lowe telling it like it is: No, AI isn't going to cure all disease www.science.org/content/blog...science.orgThe End of Disease 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 18/04/2025In 1994, an obscure jellyfish protein was stuck into a worm. It has enlightened biology and medicine ever since. 🧬 🧪 #HistSci www.omic.ly/jelly-fish-p...omic.lyJelly fish proteins started brightening up microscopy in 1994In 1994, an obscure jellyfish protein was stuck into a worm. It has enlightened biology and medicine ever since. 0204
Brian Krueger, PhD @h2so4hurts.bsky.social · 18/04/2025this link got truncated and doesn't go to the post 😭 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 18/04/2025HAHA, as long as you pronounce it econ-Omics I'll allow it... 000
Brian Krueger, PhD @h2so4hurts.bsky.social · 18/04/2025I made a feed for all things Omics! Have your posts included in it by adding a 🧬plus any additional omics related emoji🧪🧫🔬🖥️💉🦠🥼. Anything Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, or Metagenomics related (or adjacent!) is welcome! bsky.app/profile/h2so... 183
Brian Krueger, PhD @h2so4hurts.bsky.social · 17/04/2025The importance of taking out the trash: An overview of cellular protein degradation pathways. 🧬 🧪 www.omic.ly/the-proteaso...omic.lyThe proteasome and lysosome decide what proteins live or dieThe importance of taking out the trash: An overview of cellular protein degradation pathways. 062
Brian Krueger, PhD @h2so4hurts.bsky.social · 16/04/2025HOT TAKE: Dire wolves are still very much extinct, Illumina is dumping its smallest sequencer, and PacBio finally sees the light www.omic.ly/de-extincted...omic.lyDe-extincted" Dire Wolves, A Discontinued Sequencer, and PacBio Goes LongHOT TAKE: Dire wolves are still very much extinct, Illumina is dumping its smallest sequencer, and PacBio finally sees the light 050
Brian Krueger, PhD @h2so4hurts.bsky.social · 15/04/2025Deep brain structures play a key role in filtering out what we perceive 🧬 🧪 www.omic.ly/how-does-the...omic.lyHow does the brain control perception of everything around us?Deep brain structures play a key role in filtering out what we perceive 021
Brian Krueger, PhD @h2so4hurts.bsky.social · 14/04/2025Interesting especially considering they have this thing with Biomerieux: www.biomerieux.com/us/en/journa...biomerieux.combioMérieux makes strategic investment in Oxford NanoporeOxford Nanopore Technologies plc (LSE: ONT) (“Oxford Nanopore”), the company delivering a new generation of nanopore-based molecular sensing technology, and bioMérieux SA, a world leader in the field ... 031
Brian Krueger, PhD @h2so4hurts.bsky.social · 12/04/2025Maybe we should just learn to not believe tech bros when they pretend to know science? cen.acs.org/biological-c...cen.acs.orgDire wolf debate raises concerns on scientific overhypeEven de-extinction advocates say that Colossal Biosciences’ claims are misleading 0295
Brian Krueger, PhD @h2so4hurts.bsky.social · 11/04/2025The Lac Operon showed us that gene expression can be regulated 🧬 🧪 #histsciomic.lyThe Lac Operon showed us that gene expression can be regulated'If gene expression determines the function of a cell, it must be important to control that process?' Yes, very! Let me tell you about the PaJaMo experiment. 061
Brian Krueger, PhD @h2so4hurts.bsky.social · 10/04/2025Translating the Proteome: There’s more to making proteins than just transcribing DNA into mRNA. 🧬 🧪omic.lyTranslation complicates the proteome, big time!Translating the Proteome: There’s more to making proteins than just transcribing DNA into mRNA. 061
Brian Krueger, PhD @h2so4hurts.bsky.social · 09/04/2025In a development that should surprise no one, population scale exome screening finds actionable variants. 🧬 🧪omic.lySequencing exomes in healthy populations pays dividendsIn a development that should surprise no one, population scale exome screening finds actionable variants. 051
Brian Krueger, PhD @h2so4hurts.bsky.social · 08/04/2025Oh, good, maybe journalism isn't dead afterall. www.newscientist.com/article/2475...newscientist.comNo, the dire wolf has not been brought back from extinctionColossal Biosciences claims three pups born recently are dire wolves, but they are actually grey wolves with genetic edits intended to make them resemble the lost species 090
Brian Krueger, PhD @h2so4hurts.bsky.social · 08/04/2025Well, it also highlights how Colossal's "de-extinction" activities are more of a sideshow than science. Their technology is undoubtably cool, but mutating animals for PR and marketing is just kind of gross. 030
Brian Krueger, PhD @h2so4hurts.bsky.social · 08/04/2025www.scientificamerican.com/article/dire...scientificamerican.comDire Wolves Were Not Really Wolves, New Genetic Clues RevealThe extinct giant canids were a remarkable example of convergent evolution 120
Brian Krueger, PhD @h2so4hurts.bsky.social · 04/04/2025Horseshoe crab blood is our first line of defense against endotoxin contamination of surgical tools and medical devices. Seriously. 🧬 🧪omic.lyHorseshoe crab blood to the rescue!Horseshoe crab blood is our first line of defense against endotoxin contamination of surgical tools and medical devices. Seriously. 090
Brian Krueger, PhD @h2so4hurts.bsky.social · 03/04/2025Proteoforms: This is where things start to get complicated. 🧬 🧪omic.lyProteoforms make proteomics infinitely more complicated than genomicsProteoforms: This is where things start to get complicated. 062
Brian Krueger, PhD @h2so4hurts.bsky.social · 02/04/2025They recommended me a janitorial position once and I was like, maybe that would be a reasonable career change. 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 01/04/2025Brain storming about nanopore based protein sequencing generates new hypotheses to test 🧬 🧪omic.lyWill nanopores enable single molecule protein sequencers?Brain storming about nanopore based protein sequencing generates new hypotheses to test 050
Brian Krueger, PhD @h2so4hurts.bsky.social · 28/03/2025While chromosomes are usually depicted as X's, they actually spend most of their time jumbled up like a giant ball of yarn. #HistSci 🧬 🧪omic.lyHi-C showed us that the genome has topologyWhile chromosomes are usually depicted as X's, they actually spend most of their time jumbled up like a giant ball of yarn. 071
Brian Krueger, PhD @h2so4hurts.bsky.social · 27/03/2025The Proteome: we can’t live without it, but, what actually is it? 🧬 🧪omic.lyThe proteome is so hot right nowThe Proteome: we can’t live without it, but, what actually is it? 160
Brian Krueger, PhD @h2so4hurts.bsky.social · 26/03/2025Clinical evidence is still desperately needed to justify the high cost of liquid biopsy based screening tests (Premium Content)omic.lyLiquid Biopsies, are we just faking it until we make it?HOT TAKE: Clinical evidence is still desperately needed to justify the high cost of liquid biopsy based screening tests 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 26/03/2025I see rambling like a complete moron has caught on again this presidential cycle. 000
Brian Krueger, PhD @h2so4hurts.bsky.social · 25/03/2025Ahhhh, ok, that makes much more sense!! I love my Samsung Galaxy Ultra phones. Also a big fan of OnePlus but they're not quite as nice as the Samsung flagships! 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 25/03/2025Probably not. www.reuters.com/business/hea...reuters.comNovo Nordisk expands discounted Wegovy to all cash-paying US customersNovo Nordisk said on Monday all eligible cash-paying customers in the United States can buy its weight-loss drug Wegovy at a discounted price of $499 per month at their local pharmacy. 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 25/03/2025The quest to find better tolerated weight loss drugs is well on its way and computational drug discovery has already identified at least one promising candidate! 🧬 🧪omic.lyIn silico identification of a side effect free weight loss peptideThe quest to find better tolerated weight loss drugs is well on its way and computational drug discovery has already identified at least one promising candidate! 250
Brian Krueger, PhD @h2so4hurts.bsky.social · 25/03/2025You haven't had a phone before? Or you broke a 13 year old phone? I can't comprehend either of those... 100
Brian Krueger, PhD @h2so4hurts.bsky.social · 24/03/2025You know this is the right thing for their customers when in the title they say the purpose of the sale is to "maximize stakeholder value." Delete your data NOW. 🧬🧪 investors.23andme.com/news-release...investors.23andme.com 02610
Brian Krueger, PhD @h2so4hurts.bsky.social · 21/03/2025Histones were once thought to just be dumb structural proteins that held chromatin together; now we know that the ‘histone code’ is a major regulator of gene expression. #histSci 🧬 🧪omic.lyThe formulation of the histone code forever changed our view of the genomeHistones were once thought to just be dumb structural proteins that held chromatin together; now we know that the ‘histone code’ is a major regulator of gene expression. 0225
Brian Krueger, PhD @h2so4hurts.bsky.social · 20/03/2025One thing we constantly battle in genomics is, “What does it all mean?” 🧬 🧪omic.lyJust because it's in your genes, doesn't mean it's your fateOne thing we constantly battle in genomics is, “What does it all mean?” 070
Brian Krueger, PhD @h2so4hurts.bsky.social · 19/03/2025There's always PFGE... www.bio-rad.com/en-us/catego...bio-rad.comPulsed Field Gel Electrophoresis SystemsExplore Bio-Rad's pulsed-field gel electrophoresis systems: instruments, software, and supplies designed to ensure consistency and run-to-run reproducibility. 010
Brian Krueger, PhD @h2so4hurts.bsky.social · 19/03/2025China gives Illumina some bad news and bans the import of their sequencers (Premium Content)omic.lyTurnabout is fair play as Illumina gets caught up in a trade war kerfuffleChina gives Illumina some bad news and bans the import of their sequencers 020
Brian Krueger, PhD @h2so4hurts.bsky.social · 19/03/2025I do realize the president can engage in conflicts, but he can't declare war and congress controls the appropriations process so once the money runs out, it doesn't matter what Donny wants to do. 100