New link between the gut Microbiome, bile acids and Osteoarthritis :
Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling | Science
www.science.org/doi/10.1126/...
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Osteoarthritis treatment via the GLP-1–mediated gut-joint axis targets intestinal FXR signaling
Whether a gut-joint axis exists to regulate osteoarthritis is unknown. In two independent cohorts, we identified altered microbial bile acid metabolism with reduced glycoursodeoxycholic acid (GUDCA) i...