iiinova — where your digital self keeps evolving

gregmoseley.bsky.social

@gregmoseley.bsky.social

85 followers 66 following 3 posts

Posts Replies Media

gregmoseley.bsky.social @gregmoseley.bsky.social · 05/11/2025

Congrats to Steve, Shatabdi, Ashish and excellent collaborators on this new paper... molecular smarts of viral proteins. @monashuniversity.bsky.social @ausvirologysoc.bsky.social www.nature.com/articles/s41...

Conformational dynamics, RNA binding, and phase separation regulate the multifunctionality of rabies virus P protein - Nature Communications

Viral proteins can achieve high multifunctionality, but mechanisms are poorly understood. This study shows structural flexibility of rabies virus P protein enables RNA binding and phase separation to ...

gregmoseley.bsky.social @gregmoseley.bsky.social · 21/03/2025

Congratulations and thanks to all involved on this one...! Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein | Science Signaling www.science.org/doi/10.1126/...

Structural analysis reveals how tetrameric tyrosine-phosphorylated STAT1 is targeted by the rabies virus P-protein

The cryo-EM structure of a DNA-bound STAT1 tetramer shows how it can be antagonized by a viral protein.

000

gregmoseley.bsky.social @gregmoseley.bsky.social · 31/12/2024

Congrats to Jing, Paul et al... www.sciencedirect.com/science/arti...

sciencedirect.com

Analysis of mechanisms of the rabies virus P protein-nucleocapsid interaction using engineered N-protein peptides and potential applications in antivirals design

The Phosphoprotein (P protein) of the rabies virus has multiple roles in virus replication. A critical function is to act as a cofactor in genome repl…