Reposted by Grayson S. Hamrick
1/ What's the worst enemy of a plasmid? Another plasmid! Our new study demonstrates synthetic plasmids engineered as "Trojan horses" to eliminate plasmids encoding antibiotic resistance. @dukeubme.bsky.social www.science.org/doi/10.1126/...
science.org
A predatory gene drive for targeted control of self-transmissible plasmids
A biological “denial-of-spread” (DoS) strategy leverages retrotransfer to eliminate target plasmids in microbial communities.