gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. The same applies to holidays, during which I completely disconnect from the lab. I have always avoided reading emails on my phone, limited my use of WhatsApp with lab members, and rarely communicate with them outside of working hours. 000
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. For me, this has never been a significant hurdle. 010
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. Science doesn’t typically require urgent, minute-to-minute decision-making like in commercial or financial trading. Only on rare occasions, perhaps when facing a specific deadline, and usually involving collaborators in time zones with more than a six-hour difference—does urgency become a factor 131
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20253. I don’t think there’s a single formula that works for everyone. It tends to evolve naturally (including the fuel $) as the newly established lab begins to take shape. 010
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. Some might prefer to hear about results from lab members just once every couple of months during seminars (which is not my approach), while others may choose to check in more frequently, depending on the individual and the complexity of the project 110
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. I believe it largely depends on the leadership style, abilities, and preferences of the lab head—assuming unlimited funding, which is rarely the case. For example, it varies based on how closely the lab head wants to stay involved in each project. 131
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20253. Don’t let uncertainty about spending your entire life in academia stop you from pursuing one. No one can anticipate every turn ahead. 010
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. Identifying and pursuing that path takes effort, and there’s no shortcut: hard work is what gets you to good places, including personal satisfaction. I shall add that doing a PhD is an invaluable asset, not only for an academic career but for many other paths as well. 110
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. Love what you do, and you’ll never have to go to work. Seriously, find what you’re good at, and from there, discover what you enjoy most. Liking something isn’t enough on its own, you also need to make sure you have the skills, or that you're in a position to develop them. 141
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20254. it’s important to remember that the success of protein structure prediction rests on more than 75 years of experimental research. The good news is that RNA biophysics still holds vast unexplored territory—where experimental work and AI can advance together, hand in hand. 020
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20253. (a term that reflects the need to define RNA by what it doesn’t do) are clearly functional molecules that adopt complex three-dimensional structures to carry out their roles. While AI-based prediction methods will undoubtedly enhance our understanding of RNA structure and function, 120
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. there was an overreliance on the assumption that structural insights could be obtained mainly through base-pairing predictions—hairpins being one of the few commonly considered structural features. Today, “mysterious” non-coding RNAs 110
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. In my view, RNA experimental biophysics has lagged behind the progress made in protein research, largely because RNA was, until relatively recently, regarded primarily as a carrier of genetic information. As a result, 141
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. Throughout my career, I have maintained a clear boundary between work and personal life. I have never read work emails outside of weekday working hours, and never at home—except in truly exceptional cases, perhaps once or twice a year. 131
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20253. I believe this reflects a combination of factors, including scale, national policies, and the challenges of being geographically distant from the mainstream of scientific activity—such as meetings, editorial boards, and grant networks. 010
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. In particular, the expense of traveling to international scientific meetings. Despite these limitations, Argentina has produced three Nobel laureates in biochemistry and biomedicine—an achievement not only unique in Latin America but also rare in the Southern Hemisphere as a whole. 120
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. Argentina’s investment in research and development fluctuates between 0.3% and 0.5% of its GDP—significantly lower than that of economically developed countries. This challenge is compounded by the higher cost of materials 141
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/2025I honestly cannot think of anything I would have done differently. Boring, but true. 021
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20254. which now shapes my current interest in viral mechanisms, while my drive to understand biology through a biochemical and biophysical lens remains unchanged 010
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20253. such as protein folding, intrinsic disorder, protein-nucleic acid and protein-protein recognition, aggregation, and oligomerization. My approach has always been multidisciplinary. All of this has naturally led me into the field of biomolecular condensation, 110
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. In pursuing this, I have studied aspects that contribute to our understanding of the biochemical mechanisms of two medically relevant model viruses, while simultaneously addressing fundamental questions in protein science 110
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. I can't point to a single big accomplishment—much like many musicians or filmmakers, I find it difficult to choose just one defining piece of work. Perhaps it would be my research on viruses as minimal biological entities that offer a chemical perspective on life. 131
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. I decided to take a course in soil biochemistry at a research institute, where I first learned what pursuing a PhD was really about. 020
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. At the end of my clinical biochemistry degree, I realized that most of my classmates were focused on clinical laboratory practice, while I was drawn to the more fundamental courses, such as physical biochemistry. 131
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20252. only to discover toward the end that I was not drawn to biochemical practice either, but rather to understanding the fundamental principles of biology through biochemistry.bsky.app 010
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/2025only to discover toward the end that I was not drawn to biochemical practice either, but rather to understanding the fundamental principles of biology through biochemistry. 010
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/20251. My initial motivation to understand how the human body works led me to consider pursuing a medical degree. However, I soon realized that I was not interested in treating patients. I then began a degree in clinical biochemistry, cont. 131
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/2025In pursuing this, I have studied aspects that contribute to our understanding of the biochemical mechanisms of two medically relevant model viruses, while simultaneously addressing fundamental questions in protein science—such as protein folding, intrinsic disorder, 000
gonzprat.bsky.social @gonzprat.bsky.social · 28/03/2025I can't point to a single big accomplishment—much like many musicians or filmmakers, I find it difficult to choose just one defining piece of work. Perhaps it would be my research on viruses as minimal biological entities that offer a chemical perspective on life. 100
