Sign in

GMbC

@globalmicrobiome.bsky.social
59 followers 29 following 20 posts

The GMbC is an international consortium of scientists and communities working together to advance microbiome science equitably and ethically. microbiomeconservancy.org

PostsRepliesMedia
Reposted by GMbC
Sean Gibbons 🦠💩 @gibbological.bsky.social · 08/07/2026
Great write-up on the @globalmicrobiome.bsky.social 🤩🦠 www.nytimes.com/2026/07/08/m...
nytimes.com
The Unknown Universe Inside Your Gut
172
GMbC @globalmicrobiome.bsky.social · 09/07/2026
We can't understand the human microbiome if most of humanity is missing from the data That's why we work with researchers and communities around the world to preserve microbial diversity and advance microbiome science for all Honored to be featured in @nytimes.com www.nytimes.com/2026/07/08/m...
nytimes.com
Our Bacteria Are Talking. We’ve Just Begun to Understand What They’re Saying.
042
GMbC @globalmicrobiome.bsky.social · 08/07/2026
thank you @gibbological.bsky.social !
010
GMbC @globalmicrobiome.bsky.social · 28/01/2026
Poop plays a much bigger role in health than most people realize. 🧫 A National Geographic deep dive on how gut microbes shape health, and what happens when diversity disappears. www.nationalgeographic.com/science/arti... #microbiome #science
nationalgeographic.com
Researchers are unlocking the healing powers of... poop
Scientists have discovered that gut-born bacteria may hold the secret for treatments of everything from IBD to Parkinson’s disease. Now they just need samples from the people living in the most isolat...
010
GMbC @globalmicrobiome.bsky.social · 24/11/2025
Grateful to see the GMbC featured in Nature! 🌍🧬 The article highlights our mission, community partnerships, and how we turn everyday waste into meaningful science. Huge thanks to everyone who makes this work possible. www.nature.com/articles/d41...
nature.com
Waste not: how researchers harness pee and poo for science
It might seem gross, but these materials are treasure troves for research.
010
GMbC @globalmicrobiome.bsky.social · 12/11/2025
... and the other one that discovers that shifts in the gut microbiome linked to urbanization impact host gene expression (in collaboration with @blekhman.bsky.social & @fluca2406.bsky.social): www.biorxiv.org/content/10.1...
biorxiv.org
Host transcriptional responses to gut microbiome variation arising from urbanism
Gut microbiomes of urban communities are compositionally different from their rural counterparts, and are associated with immune dysregulation and gastrointestinal disease. However, it is unknown whet...
020
GMbC @globalmicrobiome.bsky.social · 12/11/2025
This work is accompanied by two other studies, one showing that industrialization drives convergent microbial and physiological shifts in the human metaorganism: www.biorxiv.org/content/10.1...
biorxiv.org
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
These findings show that gut bacteria are not passive passengers — they are actively evolving with their human hosts, mirroring the ecological pressures of their industrialized or non-industrialized host environments.
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
... as well as: within- and between-species convergent positive selection in key functions; within- and between-species convergent allelic variants in stress-response, cell-envelope, and metabolic genes
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
Across species of Bacteroides, Parabacteroides, and Blautia, strains from industrialized hosts show: larger proteomes, associated with recent increases in gene transfer and more fluid pangenomes...
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
Isolate genomes revealed richer functional content and mobile genetic elements than paired MAGs from the same hosts and species, allowing us to detect fine-scale evolutionary changes.
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
We built a collection of 6,000 cultured gut bacterial genomes from 9 countries included in the GMbC cohort, and compared their evolution across host lifestyles.
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
Do gut bacteria evolve differently in industrialized vs. non-industrialized humans? Our new study reveals that industrialization drives parallel genomic adaptations across gut bacterial species worldwide: www.biorxiv.org/content/10.1... #microbiome #globalhealth #GMbC #genome #evolution
biorxiv.org
Convergent genomic responses of human gut bacteria to variations in industrialization
To what extent gut bacteria respond to the distinct ecological pressures imposed by human lifestyle remains unclear. Here, we investigate how genomic adaptation in gut bacteria differ between industri...
163
GMbC @globalmicrobiome.bsky.social · 12/11/2025
... and the other one that discovers that shifts in the gut microbiome linked to urbanization impact host gene expression (in collaboration with @blekhman.bsky.social & @fluca2406.bsky.social): www.biorxiv.org/content/10.1...
biorxiv.org
Host transcriptional responses to gut microbiome variation arising from urbanism
Gut microbiomes of urban communities are compositionally different from their rural counterparts, and are associated with immune dysregulation and gastrointestinal disease. However, it is unknown whet...
010
GMbC @globalmicrobiome.bsky.social · 12/11/2025
This work is accompanied by 2 other studies, one showing that industrialization drives parallel genomic adaptations in gut bacteria: www.biorxiv.org/content/10.1...
biorxiv.org
Convergent genomic responses of human gut bacteria to variations in industrialization
To what extent gut bacteria respond to the distinct ecological pressures imposed by human lifestyle remains unclear. Here, we investigate how genomic adaptation in gut bacteria differ between industri...
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
Our results highlight the need for globally inclusive microbiome research to ensure discoveries translate across all human populations.
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
These shifts occur independently of other determinants of the microbiome, such as host genetics, geography, and diet. Microbiome-based disease models trained on industrialized populations also fail to generalize globally.
120
GMbC @globalmicrobiome.bsky.social · 12/11/2025
We uncover convergent microbial and immune responses to industrialized lifestyles - specifically a loss of microbial diversity, the homogenization of gut communities, reduced community stability, elevated gut stress markers and increased IgA secretion, and altered immune-microbe interactions
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
Generating new data from >1,000 participants across 12 countries and 35 localities worldwide, we combined gut metagenomics, host genotyping, IgA-seq, lifestyle, diet, and biomarkers to build a multidimensional picture of the human metaorganism — the host and its gut microbiome together.
110
GMbC @globalmicrobiome.bsky.social · 12/11/2025
How does industrialization and lifestyle impact our interactions with gut microbiomes? And what is the consequence of these perturbations on our physiology? Discover findings from our new study addressing these questions: www.biorxiv.org/content/10.1... #microbiome #globalhealth #GMbC
biorxiv.org
195
GMbC @globalmicrobiome.bsky.social · 08/07/2025
New publication from the Global Microbiome Conservancy @mmmicrobiomelab.bsky.social! Leveraging our dataset from Peninsular Malaysia, we report a clear stratification of microbial community structure, diversity and composition, along the rural–urban gradient. www.nature.com/articles/s41...
nature.com
Gut microbiota profiles of peninsular Malaysian populations are associated with urbanization and lifestyle - Scientific Reports
Scientific Reports - Gut microbiota profiles of peninsular Malaysian populations are associated with urbanization and lifestyle
131
Reposted by GMbC
Julien Tap @julientap.bsky.social · 18/01/2025
#microbiome "Here we showed that seasonal shifts between the Prevotella- and Bifidobacterium/Ruminococcus-driven community types, or ecological states [...] particularly in fermented milk consumers." in Indian agrarian individuals. www.nature.com/articles/s41...
nature.com
Fermented foods affect the seasonal stability of gut bacteria in an Indian rural population - Nature Communications
Here, the authors profile the gut microbiota and metabolites of Indian agrarians to understand the impact of fermented foods consumption, and identify seasonal variation in the gut microbiota structur...
073
Reposted by GMbC
Nature Portfolio @natureportfolio.nature.com · 18/01/2025
With the Declaration of Helsinki now mandating community engagement, Nature Medicine asks three winners of the Nature Awards for Inclusive Health Research to share their tips. #Medsky 🧪
go.nature.com
How citizen scientists and community engagement boost the impact of health research
With the Declaration of Helsinki now mandating community engagement, Nature Medicine asks three winners of the Nature Awards for Inclusive Health Research to share their tips.
12711
Reposted by GMbC
Thulani Makhalanyane @thuls.bsky.social · 18/01/2025
Check out our work on Antarctic innate immune systems: eur03.safelinks.protection.outlook.com?url=https%3A...
eur03.safelinks.protection.outlook.com
033