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Geng-Jen Jang

@gjjang.bsky.social
49 followers 44 following 2 posts

A postdoctoral scientist at MPI-IE (previously worked at JIC) Biomolecular condensates/RNA granules/Epigenetic and co-transcriptional mechanisms

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Reposted by Geng-Jen Jang
brangwynnelab.bsky.social @brangwynnelab.bsky.social · 12/07/2025
Congrats to Jing @jesszhiyuezhao.bsky.social‬ & @dnamystrom.bsky.social‬ on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates. #CellBiology #Chromatin #PhaseSeparation rdcu.be/evWxR
rdcu.be
Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior
Nature Communications - Chromatin heterogeneity in the cell nucleus modulates the size, mobility, and formation of biomolecular condensates; decreasing chromatin heterogeneity correlates with...
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Reposted by Geng-Jen Jang
Miguel Montez @miguelmontez.bsky.social · 21/02/2025
We are happy to share our work on local #nucleosome dynamics integrating #temperature inputs into an #epigenetic switching mechanism. ⚠️ Preprint alert!! www.biorxiv.org/content/10.1...
biorxiv.org
Cold-induced nucleosome dynamics linked to silencing of Arabidopsis FLC
Temperature influences nucleosome dynamics, and thus chromatin, to regulate gene expression. Such mechanisms underlie the epigenetic silencing of Arabidopsis FLOWERING LOCUS C (FLC) by prolonged cold....
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Geng-Jen Jang @gjjang.bsky.social · 28/02/2025
Our paper has been published! We used in vivo single-particle tracking to demonstrate that the assembly of core FCA oligomers into functional macromolecular condensates. Thanks to all the authors and colleagues!
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