Reposted by Gillian Forbes
A cost-effective method for finding cis-regulatory elements in a large genome (Parhyale, 3.6 Gb), combining info from chromatin accessibility (bulk & single-nucleus ATACseq) and cross-species sequence conservation (low coverage sequencing from 3 additional Parhyale species)
Now published in eLife!
elifesciences.org
Genome-wide discovery of cis-regulatory elements in a large genome
Integrating genome-wide maps of chromatin accessibility and sequence conservation provides an accessible low-cost approach for identifying cis-regulatory elements in large genomes, validated in the em...
