Online in JCO, impact of TP53mut in DLBCL, a group of patients deserving better therapy. Provocative findings regarding how BTKi might improve their outcome. Congrats to Munna Uppal and Coll
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Integrative Molecular Analysis Reveals Determinants of Clinical Outcomes in <i>TP53</i>-Mutated Diffuse Large B-Cell Lymphoma
PURPOSEMutations in TP53, detected in over 20% of diffuse large B-cell lymphomas (DLBCLs), are associated
with poor prognosis. However, clinical outcomes among patients with TP53-mutant disease vary, ...