The interventional effects approach to causal mediation analysis is increasingly common in epidemiologic research given its potential to address policy-relevant questions about hypothetical mediator interventions. Multiple imputation is widely used for handling multivariable missing data in epidemio …

These patterns of vaping and smoking in young Australians affirm that regulations and public health initiatives are urgently needed to prevent uptake of all nicotine and tobacco products.

Observational epidemiological studies commonly seek to estimate the causal effect of an exposure on an outcome. Adjustment for potential confounding bias in modern studies is challenging due to the p...

Causal inference is the goal of randomized trials and many observational studies. The first step in a formal causal inference framework is to define the causal estimand, and in both types of study thi...

Many epidemiological questions concern potential interventions to alter the pathways presumed to mediate an association. For example, we consider a study that i...

Abstract. In studies describing socioeconomic inequities in health outcomes, the choice of estimand and the planned analytic approach are central to the in

miologic studies. However, guidance is lacking on best practice for using multiple imputation when estimating interventional mediation effects, specifically regarding the role of missingness mechanism...

2025 CEBU course timetable at MCRI. Enhance your research skills with our short courses in clinical research methods, data management, and statistical analysis.

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Longitudinal studies are frequently used in medical research and involve collecting repeated measures on individuals over time. Observations from the same individual are invariably correlated and thu....

Moreno-Betancur et al.1 report and correct here errors in their article “Canonical causal diagrams to guide the treatment of missing data in epidemiologic

Abstract. Longitudinal cohort studies, which follow a group of individuals over time, provide the opportunity to examine causal effects of complex exposure

For children with FN, there was no definite evidence that TTA ≥60 min from hospital triage (but within 2 h), increased risk of adverse outcome or prolonged hospital admission. This study has important...