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GK

@georgekarag.bsky.social
125 followers 215 following 153 posts

Occasional minion and Dr Chef of Chemistry. Dabbling in organic synthesis, python, automation, and anything I can get my hands on. ORCID: 0000-0001-5088-6047

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Reposted by GK
European Commission @ec.europa.eu · 19/07/2026
Spain plays. Europe cheers. 🙌 Good luck tonight, from every corner of the EU. Vamoooos 💪 🇪🇸
Promotional graphic featuring the Spain men's national football team posing for a group photo on the pitch. The text above them reads "¡VAMOS, ESPAÑA!" in large white letters. The European Union flag is in the bottom right corner.
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GK @georgekarag.bsky.social · 05/07/2026
This did make me giggle...
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Ursula von der Leyen @vonderleyen.ec.europa.eu · 30/06/2026
Congratulations and Ευχαριστώ dear Nikos Christodoulides. The Cypriot presidency was a real success. You drove forward our EU agenda, from competitiveness to enlargement. Abroad, you built bridges with our partners in the Middle East at a crucial moment.
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GK @georgekarag.bsky.social · 22/06/2026
Amen!
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GK @georgekarag.bsky.social · 20/06/2026
Αυτά να λέγονται!
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Mike Luckovich @mluckovich.bsky.social · 18/06/2026
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GK @georgekarag.bsky.social · 14/06/2026
This is a real threat to national health!
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GK @georgekarag.bsky.social · 11/06/2026
"If..." It's already spread to markets...
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GK @georgekarag.bsky.social · 01/06/2026
At least some of us are sensible to look ahead. As a Cypriot by birth and recently naturalised Brit I hope this is a move of hoping for the best and preparing for the worst...
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GK @georgekarag.bsky.social · 09/05/2026
A web page just told me everything it learned about me without asking. It knew my city, my device, my GPU, and how long I hesitated before scrolling. sinceyouarrived.world/taken
sinceyouarrived.world
taken.
A web page that tells you what your browser gave away the moment you arrived. No login, no form, no permission. Most pages do this. None of them tell you.
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Greg Landrum @greglandrum.bsky.social · 27/03/2026
Free registration for the 2026 #RDKit UGM (both in-person and online attendance) is now open: www.eventbrite.com/e/1985889262...
eventbrite.com
15th RDKit UGM 2026
2026 RDKit User Group Meeting (in person and online)
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GK @georgekarag.bsky.social · 07/03/2026
Marvelous work!!
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GK @georgekarag.bsky.social · 14/02/2026
This is not surprising but still chilling to read about.
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GK @georgekarag.bsky.social · 01/02/2026
This is 100 years backwards...
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GK @georgekarag.bsky.social · 01/02/2026
New post is up after a while: chemicalg.github.io/2026/02/01/C... Getting commercial availability info by compound name/synonym. @apahl.bsky.social @iwatobipen.bsky.social @greglandrum.bsky.social
chemicalg.github.io
Commercial Availability
I recently run into the problem of needing to know on demand whether a compound or reagent is commercially available using only a given name.
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GK @georgekarag.bsky.social · 28/12/2025
Dropwise Addiction
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Reposted by GK
Greg Landrum @greglandrum.bsky.social · 14/12/2025
This week's #RDKit blog post, like last week's, looks at creating your own synthon spaces. Last week was BRICS, this week we use some combichem reactions: greglandrum.github.io/rdkit-blog/p...
greglandrum.github.io
Building synthon spaces with combinatorial reactions – RDKit blog
A frequently requested tutorial part 2
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GK @georgekarag.bsky.social · 12/10/2025
New blog post is up: chemicalg.github.io/2025/10/03/F... I was looking at functional group recognition. Let me know what you think. @iwatobipen.bsky.social @apahl.bsky.social @greglandrum.bsky.social @rdkit.bsky.social
chemicalg.github.io
Functional Group Filter
Here is a problem I have come across recently:
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Reposted by GK
BladeoftheSun @bladeofthes.bsky.social · 21/08/2025
Norway is a Socialist Country It has the largest Government surplus in the world at £2tn with a population of only 5.5m. The UK has a debt of £3tn It is the happiest country in world, has the best railways in Europe and taxes all fossil fuels at 78%
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Python Hub @pythonhub.dev · 15/08/2025
I built an offline, open‑source desktop Pixel Art Editor in Python github.com/danterolle/tilf
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GK @georgekarag.bsky.social · 13/08/2025
Chemists eyes no longer need spectacles!!!
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GK @georgekarag.bsky.social · 09/08/2025
"PhD level expert ..." Well everyone had to start from somewhere before getting their PhD. I am not sure anyone with a PhD in Chemistry started from there though
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v e l o c i t y @velocity69.bsky.social · 23/07/2025
Η εθνική πόλο γυναικών νίκησε 12-9 την Ουγγαρία στον τελικό του Παγκοσμίου Πρωταθλήματος Χρυσό μετάλλιο τα κορίτσια 🥇
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GK @georgekarag.bsky.social · 22/07/2025
Well that was a deep rabbit hole...
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benjamin dickman @benjamindickman.bsky.social · 22/07/2025
happy pi approximation day! mathoverflow.net/questions/67...
mathoverflow.net
Source and context of $\frac{22}{7} - \pi = \int_0^1 (x-x^2)^4 dx/(1+x^2)$?
Possibly the most striking proof of Archimedes's inequality $\pi < 22/7$ is an integral formula for the difference: $$ \frac{22}{7} - \pi = \int_0^1 (x-x^2)^4 \frac{dx}{1+x^2}, $$ where the inte...
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GK @georgekarag.bsky.social · 20/07/2025
New blog post is up: Using network graphs to visualise synthetic routes: chemicalg.github.io/2025/07/19/R...
chemicalg.github.io
Synthetic Route Graph visualisation
I have recently been looking into representing chemical routes as network graph objects and specifically directed acyclic graphs (DAGs). DAGs are a well known and established mathematical object, and ...
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Reposted by GK
Αφήνω Χιουμορίτες @kiakovos.bsky.social · 19/07/2025
Είπα να αρχίσω γυμναστική, πρώτη μερα μου λένε σκύψτε και προσπαθήστε με τις άκρες των χεριών σας να ακουμπίσετε τα δαχτυλα των ποδιών σας. Οκ λέω, είπαμε να ξεκινήσουμε να γυμναζόμαστε αλλά ας μη φτάσουμε ως τα άκρα.
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GK @georgekarag.bsky.social · 02/07/2025
Pseudo Natural Products: the gift that keeps on giving. I am amazed by how much a concept I pioneered is still growing. Full credit to the authors for showing how many opportunities are there for the taking! pubs.acs.org/doi/10.1021/...
pubs.acs.org
Pseudonatural Products for Chemical Biology and Drug Discovery
Natural product (NP) structures have provided invaluable inspiration for the discovery of bioactive compound discovery. In the pseudonatural product (PNP) concept unprecedented combinations of NP frag...
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Reposted by GK
Luca Laraia @lucalaraia.bsky.social · 23/06/2025
I am looking to hire a protein #biochemist, #biophysicist or structural biologist: efzu.fa.em2.oraclecloud.com/hcmUI/Candid... - 2-year position working on lipid transport proteins. - Experience in protein expression, purification and biochemical and biophysical assay development. Please share!
efzu.fa.em2.oraclecloud.com
Postdoctoral fellowship in protein biochemistry and biophysics - DTU Chemistry
Do you want to contribute to an exciting chemical biology project? This postdoctoral fellowship deals with the synthesis of probes aimed at studying cholesterol transport proteins in health and diseas...
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GK @georgekarag.bsky.social · 21/06/2025
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MedChemDan🧪🤖 @medchemdan.bsky.social · 14/06/2025
If automating 🤖, coding 🧑‍💻 and collaborating 🤝 are your thing, we've got a cool job for you! Applications close 26th June, so don't delay! careers.astrazeneca.com/job/gothenbu... #AutomationChemjobs #Chemjobs
careers.astrazeneca.com
Laboratory Automation Specialist (Data & Workflows) at AstraZeneca
Learn more about applying for Laboratory Automation Specialist (Data & Workflows) at AstraZeneca
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GK @georgekarag.bsky.social · 10/06/2025
Really proud to see this one out in its final form.
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GK @georgekarag.bsky.social · 05/06/2025
Newest paper out: pubs.rsc.org/en/content/a... Thank you @digital-discovery.rsc.org for a great editorial process! I am glad to see this one out.
pubs.rsc.org
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GK @georgekarag.bsky.social · 24/05/2025
Luca is an excellent scientist and a great person! Make sure you apply if you think your skills are relevant.
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Per-Ola Norrby @peonor.bsky.social · 23/05/2025
The Stockholm Declaration on Chemistry for the Future was launched today: www.stockholm-declaration.org I believe this will be an important guiding document in years to come. Please read, sign, and share!
stockholm-declaration.org
Home | Stockholm Declaration
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GK @georgekarag.bsky.social · 21/05/2025
I have started using uv for my python projects. It's the best thing ever. Handles conflicts better that conda, dead fast, interoperable. It's amazing! astral.sh/blog/uv
astral.sh
uv: Python packaging in Rust
uv is an extremely fast Python package installer and resolver, designed as a drop-in alternative to pip and pip-tools.
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GK @georgekarag.bsky.social · 21/05/2025
New blog post about how to add chemical structure to the hover tooltip of a Bokeh plot. Let me know if you find this useful or if you have any suggestions: chemicalg.github.io/2025/05/21/C...
chemicalg.github.io
Chemical Structures with Bokeh
Bokeh is a well documented and versatile visualisation package that has a python API. Check out their documentation here.
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GK @georgekarag.bsky.social · 16/05/2025
I have just discovered that @xkcd.com is on the app. I don't think I will be going to the other place for a long long time!
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GK @georgekarag.bsky.social · 03/05/2025
If you see this post your getaway vehicle
media.tenor.com
an illustration of the millennium falcon flying through the air
ALT: an illustration of the millennium falcon flying through the air
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Kit Yates @kityates.bsky.social · 27/04/2025
As Liverpool win the Premier League for the second time, they complete the opening of a quite remarkable sequence, 33 years in the making. #Fibonacci
A table showing the number of imes teams have won the Premier League in ascending order. 
The sequence goes 1, 1, 2, 3, 5, 8, 13 - the first seven terms of the Fibonacci sequence.
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Threatening Music Notation @musicnotation.bsky.social · 20/04/2025
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Per-Ola Norrby @peonor.bsky.social · 24/04/2025
Senior manager position available in medicinal chemistry at AstraZeneca Gothenburg: careers.astrazeneca.com/job/gothenbu... PS. Don't contact me, I'm not involved in hiring. Just follow the link.
careers.astrazeneca.com
Senior Director, Medicinal Chemistry Strategy at AstraZeneca
Learn more about applying for Senior Director, Medicinal Chemistry Strategy at AstraZeneca
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GK @georgekarag.bsky.social · 04/04/2025
What did the laptop have for lunch ? A byte...
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GK @georgekarag.bsky.social · 03/04/2025
Building digital tools that make your life easy(/ier) and then sharing them with others! This is one of the many great things that @digital-discovery.rsc.org is enabling!
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GK @georgekarag.bsky.social · 02/04/2025
What on earth is happening in the UK ?? Chemistry is a "luxury science" but one would have thought we had moved past those times... www.chemistryworld.com/news/chemist...
chemistryworld.com
Chemistry courses to be shut down at the University of Bradford
Closures are part of a trend seen across UK universities
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GK @georgekarag.bsky.social · 01/04/2025
Metabarons: Almost as intense as greek drama but on the other hand it's in Space.
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Tom Gauld @tomgauld.bsky.social · 30/03/2025
Happy Mother’s Day! (My cartoon for @theguardian.com books)
Title: Just in time for Mother's Day: Classic literature with added Mums 

Panel 1: Moby Dick 
"Ahab! Moby! Enough of this nonsense. Apologise to each other and if you can't get along, stay apart." says Ahab's mother, standing in a little boat and looking sternly into Moby's eye, while her son sits chastened behing her.


Panel 2: Casino Royale.
"Vodka martini, shaken not stirred... And a sweet sherry for my mother."
says James Bond. His mother calls over feom their table "Just a little one."

Panel 3: The Lord of the Rings.
"You can look for your ring after you tidy your room and walk the dog, Sauron."
says Sauron's mother, holding out the dog lead to her son, who replies "Aw, mum!".
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GK @georgekarag.bsky.social · 27/03/2025
I did a thing and now have a blog with code! Have a look at my first post looking at molecular complexity hotspots in molecular structures. Thank you to @greglandrum.bsky.social and @iwatobipen.bsky.social for being inspiring figures for this. chemicalg.github.io/2025/03/27/M...
chemicalg.github.io
Molecular Complexity Quantification
I had recently come across a post on LinkedIn discussing the evolution (or chronological increase) of molecular complexity of APIs here.
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brasidas @brasidas.bsky.social · 26/03/2025
Frame from the game Among Us with "Houthi PC Small Group" and "there is 1 atlantic editor among us" on it
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GK @georgekarag.bsky.social · 13/03/2025
Our latest paper is now line on ChemRxiv: chemrxiv.org/engage/chemr... A digital tool for liquid-liquid extractions. Going soon to a peer-reviewed journal.
chemrxiv.org
A Digital Tool for Liquid-Liquid Extraction Process Design
Aqueous liquid-liquid extractions are crucial for purifying compounds and removing impurities in the pharmaceutical industry. However, the extensive solvent space involved in such operations highlight...
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