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George Galea

@georgegalea.bsky.social

392 followers 383 following 4 posts

Researcher in Pepperkok team @EMBL, Heidelberg. All about big data, high-throughput screening, Golgi DNA damage response & endomembrane-nuclear communication

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George Galea @georgegalea.bsky.social · 21/09/2026

Very pleased to see our work highlighted in Science. Grateful to Stella Hurtley for featuring our study.

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Reposted by George Galea

EMBL @embl.org · 30/07/2026

EMBL researchers & colleagues show for the first time that the Golgi Complex plays an active role in regulating DNA repair. The research opens up new avenues for therapeutic interventions and drug development. Learn more: www.embl.org/news/science...

Fluorescent microscopy image of human cells, with RAD51C at the Golgi and the nucleus shown in magenta while the cellular cytoskeleton is shown in cyan (f-actin staining). Credit: Karolina Kuodyte/EMBL

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George Galea @georgegalea.bsky.social · 30/07/2026

New paper from our group (Pepperkok Group, EMBL Heidelberg), led together with @kuodyte.bsky.social, where we show how the Golgi complex plays an active role in regulating homologous recombination DNA repair, pointing to DNA repair as a more cell-wide process than previously appreciated.

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George Galea @georgegalea.bsky.social · 09/01/2025

We’re kicking off the year with a new preprint update! Discover how DNA repair proteins coordinate between the Golgi and nucleus. Our latest data reveal how ATM, NBN, and GMAP210 regulate RAD51C localization to drive HR repair. Thanks to @kuodyte.bsky.social & Pepperkok team @embl.org

biorxiv.org

Spatiotemporal dynamics of RAD51C between the Golgi and nucleus regulates homologous recombination and genomic stability.

Intra-organelle communication is essential for cellular homeostasis, but the coordination between nuclear processes and cytoplasmic compartments remains poorly understood. Here, we uncover a novel spa...

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George Galea @georgegalea.bsky.social · 19/12/2024

Thrilled to be part of the project showing how Dextromethorphan, an over-the-counter cough syrup, modulates membrane trafficking to mitigate lung fibrosis. Full paper: www.science.org/doi/10.1126/... Non-tech summary: www.eurekalert.org/news-release...

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