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GenSCAPE (aka Raghavan) Lab 🧬

@genscapelab.bsky.social
111 followers 241 following 9 posts

Genomic Studies of Contemporary & Ancient Populations and their Evolution Lab @ University of Chicago 🌎🌍🌏 (Posts by @MaanasaRaghavan + Raghavan Lab members)

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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 28/07/2026
The latest from the lab! What we can learn about urbanization from gut microbes from diverse communities around South Asia: www.tandfonline.com/doi/full/10....
tandfonline.com
Distinct trajectories of urbanization shape the human gut microbiome across South Asia
Human gut microbiomes respond to lifestyle transitions, yet the extent to which these responses are conserved across spatio-cultural contexts remains undercharacterized. We present the South Asian ...
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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 30/10/2025
6/n This study could not have been possible without the incredible support of the local communities in Himachal Pradesh, our archaeological collaborators, and every co-author who made this work possible - Thank you all! 🥳
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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 30/10/2025
5/n This study provides first insights into the admixture dynamics and adaptive histories at the northern frontier of the Himalayas.
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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 30/10/2025
4/n Some present-day individuals also show admixture with lowland South Asian ancestry, highlighting a dynamic history of genetic continuity and admixture in this region of the Himalayas.
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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 30/10/2025
3/n Our results show that ancient and present-day individuals from the region largely carry Tibetan ancestry (source of high-altitude adaptive introgression signal), with substantial Steppe-related ancestry observed in individuals dating from ~1,300 years ago to present times.
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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 30/10/2025
2/n We generated genome-wide data from 7 ancient (~2300–100 years old) and 10 present-day individuals from the northern Indian Himalayas, and a ~3370-year-old individual from the Central Himalayas in Nepal. 🦴🧬
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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 30/10/2025
1/n Delighted to share our newly published work in Science Advances, investigating human genetic histories at the northern frontier of the Himalayas 🧬🏔️: www.science.org/doi/10.1126/...
science.org
Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier
Ancient and present-day human genomes shed light on ~1300 years of genetic admixture and continuity in the northern Himalayas.
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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 10/06/2025
Come and check out @jaurban2204.bsky.social's PhD project now live in Current Biology!!!
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GenSCAPE (aka Raghavan) Lab 🧬 @genscapelab.bsky.social · 14/11/2024
The Genscape Lab at UChicago is now live on BlueSky!
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