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Genomic Press @genomicpress.bsky.social · 22h

Estás equivocada. Tu hermana no tiene esquizofrenia. Yo lo sabría. La enfermedad ya le había quitado a su mujer. No podía perder también a Paty. Los mismos genes. La misma casa. Una sola enfermó. Mañana es el Día Mundial de la Salud Mental ¿Por qué mi hermana? Consuelo Walss-Bass porquemihermana.com

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Genomic Press @genomicpress.bsky.social · 23/04/2026

A cinematic, amazing book that brings to the world a real-life story of love, migration, growth, tragedy, illness, and hope. #EndTheStigma #SMI #PsychiatryMatters Visit: whymysister.com

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Genomic Press @genomicpress.bsky.social · 23/04/2026

Paty was her youngest. A model. Strikingly pretty, brilliant, loved by everyone. She painted flowers in every color. Then the flowers lost their shape. Then the voices grew louder. Then it all changed. #MentalHealthAwareness #BookSky #AlleleBooks

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Genomic Press @genomicpress.bsky.social · 23/04/2026

Eugenia was born beautiful. She grew up and married young to a promising doctor in Mexico. Five children: four would go on to remarkable careers. Then the symptoms began, and the family learned to live around a mother who was not always reachable. #MentalIllness #SiblingLoss #FamilyMentalHealth

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Genomic Press @genomicpress.bsky.social · 23/04/2026

🧵Dr. Walss-Bass has written an extraordinary book, a one of a kind intimate voyage through the reality of schizophrenia, the cancer of mental illness Daniel R. Weinberger, M.D. #WhyMySister #Schizophrenia #MentalHealth

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Genomic Press @genomicpress.bsky.social · 17/03/2026

7/7 Science is political. 3 words. That is the aphorism Christian Cazares offered when asked about his life. Not a provocation: a description. His story now reaches an estimated 1.5 billion people worldwide. 🌍 Full interview: doi.org/10.61373/bm0... 🌐 genomicpress.com 📚 interviews.genomicpress.com

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Genomic Press @genomicpress.bsky.social · 17/03/2026

6/7 📰 This interview went global today. EurekAlert! press releases in 7 languages. Picked up by 120+ US television stations. Indexed in Google, ChatGPT, Bing. Entered Bloomberg Terminal. Reached 1,359 journalists across Mexico, California, and the US. 🌐 www.eurekalert.org/news-release...

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Genomic Press @genomicpress.bsky.social · 17/03/2026

5/7 Before passing his qualifying, Cazares co-founded Colors of the Brain, a nonprofit that funds scholars, and pays the highest stipends of UCSD summer programs. ⭐ Because unpaid research favors students who can work for free. That is the whole point. Colors of the Brain mentors and scholars, 2023.

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Genomic Press @genomicpress.bsky.social · 17/03/2026

4/7 🧠 His research now runs on three tracks: EEG-to-cortical-organoid correspondence in autism, transcriptomic signatures in a Rett model, and linking cortical electrophysiology to reflexive behavior in patients who cannot complete standard lab tasks. 🔬 The goal: biomarkers that can reach Calexico.

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Genomic Press @genomicpress.bsky.social · 17/03/2026

3/7 The turning point was watching his nephew with autism wait hours for a specialist in a town with no specialists. 💡 That moment pointed Cazares toward scalp EEG research: portable, affordable, no major medical center required. The science chose the instrument. Equity chose the science.

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Genomic Press @genomicpress.bsky.social · 17/03/2026

2/7 Christian Cazares grew up in Calexico, CA. First-generation college student. Paid rent with research stipends. That background did not slow him down. It became the foundation of everything he has built since. 🔗 🌎 Read the full Genomic Press Interview in Brain Medicine: doi.org/10.61373/bm0...

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Genomic Press @genomicpress.bsky.social · 17/03/2026

🧵 1/7 A kid from a US-Mexico border town where 80% of his classmates qualified for free lunch just how UCSD admits grad students, and he is using neuroscience to close the healthcare gap his own nephew faces. A Genomic Press Interview worth reading.

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Genomic Press @genomicpress.bsky.social · 20/02/2026

📰 Full feature story in News-Medical. 3/4 🔗 url.genomicpress.com/2p93a2xt

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Genomic Press @genomicpress.bsky.social · 20/02/2026

@GenomicPress highlights molecular barriers and hope. 2/4 Open Access 🔗 doi.org/10.61373/bm... 🧠

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Genomic Press @genomicpress.bsky.social · 20/02/2026

🧵 Why do promising Alzheimer's drugs keep failing? New analysis points to a fix. 1/4

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Genomic Press @genomicpress.bsky.social · 04/02/2026

8/8 Dive deeper: 📖 Full OA paper: doi.org/10.61373/pp0... 📚 Genomic Press Library: issues.genomicpress.com/bookcase/gtv... 🌐 genomicpress.com Tag @ClaireFoldi1 @ZaneBAndrews @MonashBDI for Qs. RT if you're into #PsychedelicTherapy #MentalHealth #EatingDisorders #ClaireFoldi #SheidaShadani

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Genomic Press @genomicpress.bsky.social · 04/02/2026

7/8 Early Global Coverage 🌍📰 Already making waves: • Drug Target Review: url.genomicpress.com/2p9cry6c • Medical Xpress: url.genomicpress.com/2p8j3nb3 • Labmate Online: url.genomicpress.com/2p8ac3yh • ScienMag: url.genomicpress.com/2pzmcv9a More incoming – stay tuned!

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Genomic Press @genomicpress.bsky.social · 04/02/2026

6/8 Press Releases Alert! 🚨 EurekAlert! (science journalists' hub): www.eurekalert.org/news-release... Translations available: 🇺🇸 EN | 🇪🇸 ES | 🇫🇷 FR | 🇩🇪 DE | 🇨🇳 ZH | 🇯🇵 JP EINPresswire (mass distribution): url.genomicpress.com/bdenbvs4 Hit AP News, Google News, Bing, ChatGPT databases & 200+ outlets!

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Genomic Press @genomicpress.bsky.social · 04/02/2026

5/8 Exercise history could be a biomarker for psilocybin. Food restriction disrupts inflammation-social links. @SheidaShadani: "These findings reveal subtle, context-dependent effects... underscoring the need to clarify temporal, neuroplastic, and immune mechanisms." Tailored treatments incoming? 🎯💡

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Genomic Press @genomicpress.bsky.social · 04/02/2026

4/8 Inflammation bombshell: Psilocybin spiked IL-6 in RW mice (P=0.0029), and higher IL-6 linked to more novelty preference (r=0.8020, P=0.0166). But FR wiped out this correlation entirely. In ABA? No IL-6 changes. Metabolic state flips the script on psilocybin's immune effects! 📈⚠️

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Genomic Press @genomicpress.bsky.social · 04/02/2026

3/8 Surprise #1: NO social withdrawal in ABA mice! Instead, HYPER novelty-seeking: preferred novel over familiar ones (P=0.02 vs controls). RW mice showed similar in choice phase. Challenges the "social deficits in anorexia" narrative. Psilocybin? Reduced novelty in controls only, no other shifts.🤯

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Genomic Press @genomicpress.bsky.social · 04/02/2026

2/8 Setup: 56 female C57BL/6 mice divided into 4 groups 🐭🍄🔬 • Activity-Based Anorexia (anorexia model) • Food Restriction (FR) • Running Wheel (RW) • Controls Single psilocybin dose (1.5 mg/kg IP) or saline, tested 4-5 hrs later on social preference. Rigorous, female-focused design FTW! 🧪📊

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Genomic Press @genomicpress.bsky.social · 04/02/2026

1/8 🧵 Breaking: Groundbreaking study drops in Psychedelics! Psilocybin's effects on social behavior & inflammation in female mice modeling anorexia nervosa? TOTALLY context-dependent on metabolism & exercise. Explains why only ~40% respond in human trials. Implications for personalized therapy!

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Genomic Press @genomicpress.bsky.social · 03/02/2026

7/7 His core philosophy hits hard: "Do the best you can, with the evidence you have, in the service of others." That's the mindset behind 330k+ citations. 📖 Open Access: doi.org/10.61373/gp0... 🏛️ Genomic Press library: issues.genomicpress.com/bookcase/gtv... What question would YOU ask him? 👇

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Genomic Press @genomicpress.bsky.social · 03/02/2026

6/7 Press blasts: • EurekAlert! (AAAS) 🇺🇸 EN: www.eurekalert.org/news-release... 🇪🇸 ES 🇫🇷 FR 🇩🇪 DE 🇨🇳 ZH 🇯🇵 JP 🇧🇷 PT • EIN Presswire: 388+ outlets (AP, Google News, TV/radio, AI dbs like ChatGPT/Gemini). url.genomicpress.com/46ad4ce6 Coverage: NatLawReview, Brightsurf (US), MirageNews (AU).

einpresswire.com

Ronald C. Kessler: Shining Light on the Hidden Impact of Mental Disorders on People and Communities Everywhere

Landmark surveys across 30+ countries exposed massive treatment gaps, reshaping global mental health policy

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Genomic Press @genomicpress.bsky.social · 03/02/2026

5/7 Now? From data → real-world fixes. Key projects: • SAFEGUARD: Cutting suicide in US soldiers • Menssano: Digital tools scaling campus mental health Population surveys are blueprints for saving lives. From insights to interventions. 💡 Download infographic: url.genomicpress.com/2zwndyph

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Genomic Press @genomicpress.bsky.social · 03/02/2026

4/7 🌍 The monster achievement: World Mental Health Survey Initiative • 30+ countries • 1,000+ articles • 8 book volumes Largest coordinated psych epidemiology effort ever. Kessler built it, led it for decades, now handing off to next gen. Data still drives policy worldwide.

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Genomic Press @genomicpress.bsky.social · 03/02/2026

3/7 Before Harvard fame: 3 years at NBC studying TV violence & kids' mental health—with real money & deadlines on the line. "I had to design rigorous research with millions at stake. Rapid accountability you rarely get in academia." Formative AF. That pressure forged his precision.

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Genomic Press @genomicpress.bsky.social · 03/02/2026

2/7 The pivot that changed everything: A young prof (Bill Phillips) spotted law-school-bound Ron and pushed him toward empirical research instead. Result? One of the most influential careers in psych epi. Lesson: Sometimes the best mentors see paths you don't. 🔗 doi.org/10.61373/gp0...

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Genomic Press @genomicpress.bsky.social · 03/02/2026

1/7 🧵 THREAD: The world's MOST cited researcher in psychiatry & psychology just dropped a Genomic Press Interview. Dr. Ron Kessler went from first-gen college kid dreaming of law → 1,300+ papers, 330k+ citations, reshaped global mental health policy via massive surveys in 30+ countries. His story:

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Genomic Press @genomicpress.bsky.social · 28/01/2026

8/8 Dive into the Viewpoint (Open Access) that sparked Nature's coverage: "Insights from Brazilian supercentenarians" in Genomic Psychiatry. 🔗 DOI: doi.org/10.61373/gp0... 🌐 Genomic Press is leading the charge on diverse genomics & healthy aging. Who's ready to live to 110+? 💪🧬 re-post+follow!

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Genomic Press @genomicpress.bsky.social · 28/01/2026

7/8 The goal? Decode what these genes DO → turn insights into therapies for everyone, not just the genetically lucky. Healthspan for all, inspired by Brazil's overlooked elders. 🌟

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Genomic Press @genomicpress.bsky.social · 28/01/2026

6/8 Key takeaway: Aging isn't inevitable decline—it's adaptable resilience. Preserved proteostasis, upgraded immune configs (cytotoxic CD4+ T cells!), rare variants in HLA, IL7R, autophagy, DNA repair genes. Brazil's admixed supercentenarians are rewriting the rules.

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Genomic Press @genomicpress.bsky.social · 28/01/2026

5/8 The science is next-level: • Whole-genome sequencing of 160+ centenarians (20 supercentenarians) • iPSC brain organoids, muscle/heart/lung cells • Immune profiling (robust IgG & neutralizing Abs vs COVID-19, unvaccinated in 2020!) They stayed sharp, independent, and dealt with threats.

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Genomic Press @genomicpress.bsky.social · 28/01/2026

4/8 Why Brazil? Genetic goldmine. Centuries of admixture: European + African + Native American + Japanese waves = millions of unique variants missing from global databases. Most longevity studies? Stuck on homogeneous groups. Brazil's diversity hides protective "super" genes invisible elsewhere. 🌍🧬

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Genomic Press @genomicpress.bsky.social · 28/01/2026

3/8 Meet Sister Inah: world's oldest person until 2025 (116!). Chocolate-obsessed nun who never skipped sugar or fat. 🍫🙏 Brazil also boasts 3 of the top 10 longest-lived validated MEN worldwide, including the current oldest living man. Extreme male longevity is rare... yet Brazil is crushing it.

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Genomic Press @genomicpress.bsky.social · 28/01/2026

2/8 Picture this: Laura Oliveira (106) started swimming at 70... and won her first race at 100 🏊‍♀️ Her sisters: 101 & 104. Their aunt Geny: 110. One family, FOUR centenarians/supercentenarians. Longevity clearly runs in the blood—not just the same kitchen. 🧬👵👴

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Genomic Press @genomicpress.bsky.social · 28/01/2026

🧵 THREAD 1/8 Nature just dropped a bombshell feature on Brazil's supercentenarians: people hitting 110+ without elite diets, gyms, or fancy meds. Their secret? Genes + insane resilience. And the groundbreaking research behind it? Published in Genomic Psychiatry 🔗 www.nature.com/articles/d41...

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Genomic Press @genomicpress.bsky.social · 20/01/2026

5/5 Dive in now: issues.genomicpress.com/books/oqrw/ Genomic Psychiatry website: gp.genomicpress.com 🌐 Share, read, cite – let's shape tomorrow's mental health together. Follow genomicpress.com for more. What excites you most about genomic psychiatry? Reply below! 🧠💡 #Research #Innovation

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Genomic Press @genomicpress.bsky.social · 20/01/2026

4/5 This isn't just a journal; it's a paradigm shift in publishing. Flip through interactively like a digital magazine, accessible across the world. Authors from low-income countries get APC waivers – fair, fast, and focused on breakthroughs. Join the revolution! #OpenAccess #Science

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Genomic Press @genomicpress.bsky.social · 20/01/2026

3/5 🚨 Highlights: Inaugural editorial on advancing from genes to society; insights from rising stars like Haitham Amal; thought-leader reviews on cognition in schizophrenia; new research on fragile X treatments. Plus, no paywalls – true open access under CC BY-NC-ND 4.0. Democratizing science! 📖✨

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Genomic Press @genomicpress.bsky.social · 20/01/2026

2/5 🌍🧬 Led by Julio Licinio and a stellar board featuring Nobel Laureate T Südhof, plus giants like H Akil, F. Gage, and Y Hurd. We are bridging genomics, neuroscience, AI, pharmacology, and more to tackle depression, schizophrenia, Alzheimer's, and beyond 🔥 🔗 issues.genomicpress.com/books/oqrw/

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Genomic Press @genomicpress.bsky.social · 20/01/2026

🧵 THREAD 1/5 BREAKING from Genomic Psychiatry: The future of mental health research is HERE! Introducing Genomic Psychiatry 2025: Entire Volume 1: Our revolutionary open-access e-book compiling a FULL YEAR of groundbreaking discoveries. This 434-page powerhouse is FREE to everyone, everywhere!

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Genomic Press @genomicpress.bsky.social · 09/01/2026

8/8 🤔 6.7M Americans with AD need this shift. Read it in Brain Medicine (Genomic Press): "Isoform-specific roles and overlooked complexity of AMPKα in Alzheimer's disease" 🔗 Open Access: doi.org/10.61373/bm0... 📚 issues.genomicpress.com/bookcase/gtv... 🌐 genomicpress.com Figure credit: Lbattist

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Genomic Press @genomicpress.bsky.social · 09/01/2026

7/8 🚨 Future: Develop isoform-specific, BBB-crossing drugs. Inhibit α1 to rescue? Boost α2 to prevent? Study brain regions, CNS vs peripheral roles. Precision targeting could end mixed trial results!

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Genomic Press @genomicpress.bsky.social · 09/01/2026

6/8 📊 Biomarkers ahead: Plasma α1 (not α2) LOWER in AD/MCI patients. Isoform ratios could enable early blood/CSF/imaging diagnosis. Plus, genetic α1 suppression fixes AD proteome changes in models and α2 doesn't.

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Genomic Press @genomicpress.bsky.social · 09/01/2026

5/8 ⚠️ Dual pathways: In familial AD, Aβ amps α1 → eEF2 overphosphorylation → protein synthesis halt. In late-onset, α2 loss + α1 rise → eIF2α via PERK → same translation block. End result? Memory loss. Check Figure 1 for the model!

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Genomic Press @genomicpress.bsky.social · 09/01/2026

4/8 💊 METFORMIN MYSTERY CRACKED: Diabetes drug sometimes protects, sometimes worsens AD. Why? It activates isoforms differently; e.g., nuclear α2 in some cells, cytoplasmic α1 in others. Resveratrol favors α2 (3x), GLP-1 boosts α2, carbachol hits α1.

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Genomic Press @genomicpress.bsky.social · 09/01/2026

3/8 Model evidence: In AD mice, knocking down α1 RESTORES memory, synaptic plasticity, spine density, independent of amyloid/tau. But reduce α2? Synapses fail, cognition crashes. Dr. Tao Ma: Opposing roles in brain health!

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