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GastroAGI

@gastroagi.bsky.social
62 followers 211 following 224 posts

⚡Empowering clinicians & trainees with expert GI & liver updates, clinical pearls & trending research.🌏 🔗 gastroagi.com

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GastroAGI @gastroagi.bsky.social · 08/10/2026
Missed something from WCOG 2026, New Delhi? The Postgraduate Course is now available on GastroAGI. Explore the course and revisit key GI learning topics. 🔗 gastroagi.com/chat?panel=C...
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GastroAGI @gastroagi.bsky.social · 07/10/2026
After oesophago-gastric cancer surgery, which symptoms are we still missing? The EUROSTAR consensus sharpens the focus on survivorship and follow-up. gastroagi.com/blog/eurosta...
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EUROSTAR Consensus After UGI Cancer Surgery
EUROSTAR consensus offers practical guidance for monitoring, investigating, and managing symptoms after oesophagectomy or gastrectomy.
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GastroAGI @gastroagi.bsky.social · 07/10/2026
Which AASLD TLM 2026 abstracts deserve attention—and which are still too early to change practice? gastroagi.com/blog/aasld-t...
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AASLD TLM 2026 Abstracts: Hepatology Signals
AASLD’s TLM 2026 abstract release highlights MASLD, transplant, portal hypertension, ALD, liver cancer, HBV, and cholestatic disease.
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GastroAGI @gastroagi.bsky.social · 07/10/2026
Cirrhosis care should be preventive, not just reactive. The new ACG guidance emphasizes structured surveillance, vaccination, nutrition, cognition and complication prevention. #Hepatology #Cirrhosis #ClinicalGuidelines #MedSky
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GastroAGI @gastroagi.bsky.social · 06/10/2026
Intra-abdominal fluid after appendectomy does not automatically justify postoperative antibiotics. Risk appears to depend more on the patient and disease context than fluid alone. #Appendicitis #AntibioticStewardship #MedSky #Surgery
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GastroAGI @gastroagi.bsky.social · 29/09/2026
GastroAGI is coming to New Delhi for WCOG 2026. If you’re attending, we’d be glad to meet you at our booth, hear about your experience with GastroAGI, and learn where we can improve further. 📍 New Delhi 📅 30 September – 3 October 2026 #WCOG2026 #Gastroenterology #MedSky
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GastroAGI @gastroagi.bsky.social · 29/09/2026
Does MELD reflect the same waitlist risk across liver diseases? UNOS data suggest AAH may behave differently, raising an important question about transplant prioritization. #Hepatology #LiverTransplantation #MELD #MedSky
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GastroAGI @gastroagi.bsky.social · 28/09/2026
ASCOT shows that the survival benefit of adjuvant S-1 after BTC surgery remained durable with longer follow-up. #GIOncology #BiliaryTractCancer #ClinicalEvidence #Gastroenterology #MedSky
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GastroAGI @gastroagi.bsky.social · 26/09/2026
Pancreatic enzymes treat exocrine insufficiency—but not necessarily chronic pancreatitis pain. A randomized study in Gut found no meaningful pain benefit over placebo, reinforcing the need to manage pain as a separate clinical problem. #Gastroenterology #ChronicPancreatitis #Pancreatology #MedSky
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GastroAGI @gastroagi.bsky.social · 24/09/2026
Could CRRT help before kidney failure develops in acute liver failure? Early CRRT improved ammonia clearance and early outcomes, but definitive survival benefit remains unproven. #AcuteLiverFailure #Hepatology #CRRT #MedSky
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GastroAGI @gastroagi.bsky.social · 23/09/2026
Can “drain first” always be the right approach in WON? Immediate DEN may improve clinical success and shorten hospital stay in selected patients. #WalledOffNecrosis #Endoscopy #Gastroenterology #MedSky
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GastroAGI @gastroagi.bsky.social · 22/09/2026
Can endoscopy alone identify which gastric intestinal metaplasia patients are truly high risk? A new meta-analysis puts **EGGIM ≥5** under the spotlight.
gastroagi.com
EGGIM for Extensive Gastric Intestinal Metaplasia
GIE meta-analysis found EGGIM ≥5 highly accurate for detecting extensive gastric intestinal metaplasia using NBI or BLI endoscopy.
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GastroAGI @gastroagi.bsky.social · 22/09/2026
PBC assessment is moving beyond ALP alone. The 2026 EASL–AASLD consensus keeps ALP and bilirubin central, while placing greater emphasis on fibrosis trajectory, symptoms, and multidimensional disease control. gastroagi.com/daily-brief #PBC #Hepatology #Gastroenterology #AASLD #MedSky
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GastroAGI @gastroagi.bsky.social · 21/09/2026
What if adenomas are being missed not because they are invisible—but because we are looking in the wrong place? The EYE-SIGHT trial tests whether peripheral gaze feedback can sharpen detection during colonoscopy.
gastroagi.com
EYE-SIGHT Trial: Gaze and Adenoma Detection
A multicenter RCT found real-time peripheral gaze feedback improved adenoma and polyp detection during colonoscopy without longer observation time.
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GastroAGI @gastroagi.bsky.social · 21/09/2026
Can vedolizumab trough levels actually tell us who is likely to stay in remission? A new meta-analysis asks whether therapeutic drug monitoring is ready to become more useful in everyday IBD care.
gastroagi.com
Vedolizumab TDM in IBD: New Evidence
A 2026 CGH meta-analysis links higher vedolizumab trough levels with remission in IBD, strongest for endoscopic remission in UC.
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GastroAGI @gastroagi.bsky.social · 21/09/2026
Could 5 years be enough after high-risk adenoma removal? EPoS II found similar 5-year CRC incidence with 5-year vs 3-year surveillance, but the trial is still ongoing. The real answer will come from the 10-year CRC outcomes. #ColorectalCancer #Colonoscopy #Gastroenterology #MedSky
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GastroAGI @gastroagi.bsky.social · 18/09/2026
A “normal” ferritin doesn’t always rule out iron deficiency. The new ASH guidance raises diagnostic thresholds and reinforces an important point: interpret ferritin in context—especially when inflammation is present. #IronDeficiency #Hematology #MedSky #Gastroenterology
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GastroAGI @gastroagi.bsky.social · 17/09/2026
Do high-risk adenomas really need 3-year surveillance? EPoS II asks whether 5 years could be enough—with long-term CRC outcomes ultimately deciding the answer. #Colonoscopy #ColorectalCancer #Endoscopy #MedSky
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GastroAGI @gastroagi.bsky.social · 16/09/2026
Steroid tapering in UC isn’t one-size-fits-all. A 10-week taper may improve steroid-free remission, but the schedule should reflect the accompanying maintenance therapy. #UlcerativeColitis #IBD #Gastroenterology #Medsky
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GastroAGI @gastroagi.bsky.social · 15/09/2026
Can infection be mistaken for an IBD flare? Multiplex stool PCR detected more pathogens and was associated with less IBD therapy escalation — but outcome benefit still needs prospective confirmation. #IBD #Gastroenterology #ClinicalResearch #MedSky
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GastroAGI @gastroagi.bsky.social · 14/09/2026
Could perioperative immunotherapy finally change the standard in resectable gastric cancer? MATTERHORN showed that adding durvalumab to FLOT improved overall survival, with benefit extending across pCR, EFS and OS. #Gastroenterology #GastricCancer #MedSky
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GastroAGI @gastroagi.bsky.social · 12/09/2026
What if appendiceal adenocarcinoma shouldn’t simply be treated like colon cancer? New data suggest recurrence risk varies sharply by histology—and the benefit of routine adjuvant chemotherapy may be less straightforward than assumed. Worth a closer look. #GastroAGI #Gastroenterology #Medsky
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GastroAGI @gastroagi.bsky.social · 11/09/2026
What could quietly change GI practice next? 👀 A new therapy for SBS-IF. A biomarker for complicated Crohn’s. Safer sedation in obesity. The economics of MASH screening. The interesting part is in the details. Read the latest on GastroAGI. #Gastroenterology #Hepatology #IBD #MedSky
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GastroAGI @gastroagi.bsky.social · 10/09/2026
A better way to revise GI: ask the question you actually have. From hepatitis to HCC, get focused, evidence-led answers with gastroagi.com Made for GI. Only GI. #Gastroenterology #Hepatology #MedEd #MedSky
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GastroAGI @gastroagi.bsky.social · 05/09/2026
Does cardiometabolic risk amplify the liver harm from alcohol? A Danish cohort suggests the combination may matter more than either factor alone.
gastroagi.com
Alcohol and Cardiometabolic Cirrhosis Risk
Danish cohort data show alcohol remains the dominant modifiable cirrhosis risk factor, with metabolic risks adding most at lower intake.
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GastroAGI @gastroagi.bsky.social · 05/09/2026
Which chronic liver diseases carry the greatest cholangiocarcinoma burden? A global biliary tract cancer registry reveals patterns clinicians may not expect.
gastroagi.com
Chronic Liver Disease and CCA Prognosis
GLOBAL-BTC registry data link chronic liver disease with earlier cholangiocarcinoma diagnosis, more surgery, and better survival.
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GastroAGI @gastroagi.bsky.social · 05/09/2026
Two years of elafibranor in PBC—does the early biochemical promise hold up? And what do the longer-term data tell us about durability and safety?
gastroagi.com
Elafibranor Two-Year PBC Data
ELATIVE phase III data show sustained biochemical response, symptom signals, stable fibrosis markers, and longer-term safety with elafibranor in PBC.
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GastroAGI @gastroagi.bsky.social · 03/09/2026
After advanced-therapy failure in UC, what should come next? TRIDENT-UC puts upadacitinib into a difficult real-world sequencing question—does it outperform the alternatives when options are already narrowing?
gastroagi.com
Upadacitinib After UC Therapy Failure
TRIDENT-UC real-world data suggest higher steroid-free remission with upadacitinib after advanced-therapy failure in moderate-to-severe UC.
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GastroAGI @gastroagi.bsky.social · 03/09/2026
RAS-mutant pancreatic cancer has long been one of oncology’s hardest targets. Could daraxonrasib finally make that biology therapeutically actionable—and for which patients?
gastroagi.com
Daraxonrasib for Metastatic Pancreatic Cancer
FDA approval of daraxonrasib introduces a RAS-targeted option for previously treated metastatic pancreatic adenocarcinoma.
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GastroAGI @gastroagi.bsky.social · 03/09/2026
Can a difficult cholecystectomy be predicted before the first incision? A preoperative score may help flag higher-risk cases—but which factors actually matter most?
gastroagi.com
Predicting a Hard Cholecystectomy Before You're In the Abdomen: What New TG18 Data Add to Surgical Planning
New data extend the Tokyo Guidelines 2018 difficulty score to the preoperative setting - six clinical factors that flag a hard cholecystectomy before you're in the OR
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GastroAGI @gastroagi.bsky.social · 03/09/2026
In PSC, could liver stiffness reveal progression before routine markers do? The FICUS cohort asks whether elastography can sharpen risk prediction—and identify who needs closer follow-up.
gastroagi.com
Liver Stiffness Predicts PSC Outcomes
Prospective FICUS cohort data suggest liver stiffness by FibroScan may help predict transplant-free survival in compensated PSC.
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GastroAGI @gastroagi.bsky.social · 01/09/2026
Daraxonrasib: A New RAS-Targeted Option #MedSky #gastroenterology
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Daraxonrasib: A New RAS-Targeted Option | GastroAGI
Daraxonrasib has moved RAS targeting in metastatic pancreatic cancer from promise to randomized phase 3 evidence. RASolute 302 showed meaningful improvements in overall survival, progression-free sur...
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GastroAGI @gastroagi.bsky.social · 01/09/2026
Three GI updates worth understanding today: • Frontline metastatic pancreatic cancer • Ampullary tumour management • Decompensation risk in alcohol-related cirrhosis Short, clinically focused, and built for a quick catch-up. gastroagi.com/daily-brief #Gastroenterology #Hepatology #MedSky
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GastroAGI @gastroagi.bsky.social · 31/08/2026
Sign Up: gastroagi.com/daily-brief #MedSky #gastroenterologist
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GastroAGI @gastroagi.bsky.social · 29/08/2026
Sign Up: gastroagi.com #gastroenterology #MedSky
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GastroAGI @gastroagi.bsky.social · 29/08/2026
Sign Up: gastroagi.com #gastroenterology #MedSky
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GastroAGI @gastroagi.bsky.social · 27/08/2026
Four fresh GI updates. One quick read. 👀 Today’s Daily Brief covers GIST, AI in publishing, PPI safety, and liver function testing. About 8 minutes to catch up. #GastroAGI #Gastroenterology #Hepatology gastroagi.com/daily-brief
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GastroAGI @gastroagi.bsky.social · 26/08/2026
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GastroAGI @gastroagi.bsky.social · 24/08/2026
EUS vs TIPS for Gastric Variceal Bleeding: Similar Control, Different Risks - Endoscopy | 2026 gastroagi.com/daily-brief #endoscopy
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GastroAGI @gastroagi.bsky.social · 22/08/2026
Fluoroscopy-Free Cholangioscopy: ERCP Without Radiation? #MedSky #gastroenterology
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GastroAGI @gastroagi.bsky.social · 17/08/2026
Early ileostomy closure at 2 weeks sounds attractive—but this trial found no QoL benefit, 19% anastomotic leakage vs 0%, and more complications. Earlier is not always safer. Sign up to gastroagi.com #ColorectalSurgery #RectalCancer #medsky #GastroAGI
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GastroAGI @gastroagi.bsky.social · 17/08/2026
4 GI updates. 5 minutes. Today on gastroagi.com Daily Brief covers ⬇️ #Gastroenterology #Hepatology #MedSky #GastroAGI
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GastroAGI @gastroagi.bsky.social · 13/08/2026
4 GI updates. 6 minutes. One smarter catch-up. Sign UP: gastroagi.com Take 6 minutes. Keep the evidence moving with you. #Gastroenterology #Hepatology #GIOncology #Medsky
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GastroAGI @gastroagi.bsky.social · 12/08/2026
August 12, 2026 · 4 updates · 6 min read gastroagi.com #gastroenterology #GastroAGI #MedSky
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GastroAGI @gastroagi.bsky.social · 11/08/2026
How sick is too sick for liver transplantation? In ACLF-3 on maximal life support, where does transplant benefit end—and futility begin? gastroagi.com/blog/aclf3-m... #ACLF #LiverTransplant #Hepatology
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ACLF-3 Liver Transplant Futility
A JHEP Reports study examines liver transplantation in extreme ACLF-3 patients requiring ventilation, vasopressors, and dialysis, identifying factors associated with futility.
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GastroAGI @gastroagi.bsky.social · 11/08/2026
Why treat the entire gastric varix if one feeder vessel is driving it? Precision EUS may shift the target—and possibly the strategy. gastroagi.com/blog/precisi... #EUS #GastricVarices #PortalHypertension
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Precision EUS Therapy for Gastric Varices
A 2026 Gastrointestinal Endoscopy commentary and supporting comparative study examine whether EUS-guided feeder-vessel targeting can reduce coil, glue, and reintervention requirements in selected gast...
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GastroAGI @gastroagi.bsky.social · 11/08/2026
What if cholesterol is doing more than feeding the tumor? A ZC3H15-linked pathway may help explain why pancreatic cancer becomes harder to kill. gastroagi.com/blog/cholest... #PancreaticCancer #Chemoresistance #GIOncology
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Cholesterol Metabolism in Pancreatic Cancer 2026: Why FOLFIRINOX Resistance May Start With a Lipid Pathway, Not a Mutation
New NCI-funded research links the ZC3H15-KDM3A-cholesterol axis to FOLFIRINOX resistance in pancreatic cancer, and tests rosuvastatin as a chemosensitizer.
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GastroAGI @gastroagi.bsky.social · 11/08/2026
Could regenerative medicine change how we approach persistent perianal Crohn’s fistulas? #CrohnsDisease #MedSky #Gastroenterology #GastroAGI
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GastroAGI @gastroagi.bsky.social · 07/08/2026
Your coffee can’t review today’s GI updates for you. Unfortunately. ☕ Daily Brief can help. Fresh GI evidence, key topics, and a focused read in just a few minutes. Sign up and stay up to date with GI learning. #GastroAGI #Gastroenterology #Hepatology #MedSky
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GastroAGI @gastroagi.bsky.social · 06/08/2026
Could less frequent IL-23 dosing become a practical option in ulcerative colitis? #Gastroenterology #IBD #medsky
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