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GALENOS

@galenos.bsky.social
24 followers 11 following 32 posts

A new living evidence resource of early phase research for research prioritisation in mental health.

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GALENOS @galenos.bsky.social · 27/11/2025
GALENOS researchers have found that dopamine is implicated in anhedonia, and shared their findings in a new paper published in @ebiomedicine.bsky.social Other neurotransmitters are involved as well and more research is needed to fully understand the complex causes of anhedonia. 2/3
A diagram of the neurotransmitter dopamine with text overlaid that reads: 'Dopamine is a neurotransmitter responsible for the feeling of pleasure and motivation. Low  levels of dopamine increase feelings of anhedonia.
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GALENOS @galenos.bsky.social · 27/11/2025
Anhedonia is the inability to feel pleasure from activities that are normally enjoyable, like hobbies, socialising, or eating. It’s often linked to conditions like depression and can make things feel flat or uninteresting. 🧵1/3
An orange stickman looks down sadly. Text overlaid reads: 'Anhedonia is the loss of interest or joy in life's usual rewards. It's a common symptom of depression and other mental health conditions.'
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GALENOS @galenos.bsky.social · 05/11/2025
What is anhedonia? And why does it matter for mental health research? Psychotherapist and GLEBE member Sandra helps us to understand what anhedonia is and how it impacted her life. Plus, learn about the latest research into anhedonia from GALENOS 👇 www.galenos.org.uk/blog-news/un...
Understanding anhedonia is 
very complex and in order to 
understand it better 
collaboration has to be done. 
This entails those with lived 
experience working together 
with the mental health 
professionals.
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GALENOS @galenos.bsky.social · 17/10/2025
GALENOS is investigating the effects of estrogen-based treatments in adults with SSD by compiling the existing evidence into one big systematic review. You can read more about this project, and view the evidence yourself, here: www.galenos.org.uk/blog-news/es... 5/5
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GALENOS @galenos.bsky.social · 17/10/2025
Postmenopausal women have estrogen levels that are comparable to mens. Reduced estrogen levels in women have been linked to worsening symptoms of SSD during hormonally sensitive periods such as menstruation, after childbirth (postpartum), and during menopause. 4/5
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GALENOS @galenos.bsky.social · 17/10/2025
Estrogen is a hormone that supports growth, heart health & reproduction. Women have higher levels because it’s key for female reproductive functions. Men make smaller amounts & rely more on testosterone for development. 3/5
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GALENOS @galenos.bsky.social · 17/10/2025
Men typically experience an earlier onset, often in their late teens or early twenties, while women tend to develop symptoms later in life, frequently around menopause. These observations prompted researchers to explore if increased levels of estrogen could stabilize symptoms of SSD. 2/5
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GALENOS @galenos.bsky.social · 17/10/2025
Schizophrenia spectrum disorders (SSD) affect millions of people and can cause hallucinations, feelings of detachment from reality and cause difficulties that can disrupt a persons quality of life. Decades of research have revealed key differences in how SSD develops in men & women. 🧵1/5
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GALENOS @galenos.bsky.social · 10/10/2025
GALENOS's own Gin Malhi, Andrea Cipriani & Georgia Salanti were delighted to present at #WCP2025 about literature based discovery science. They shared how GALENOS synthesizes existing evidence to reduce waste & improve efficiency in #mentalhealth research. #WorldMentalHealthDay
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GALENOS @galenos.bsky.social · 29/08/2025
"The first time I was accepted as a Lived Experience Expert at GALENOS was exciting. It felt incredibly affirming to be connected to such respected institutions as @mqmentalhealth.bsky.social and @ox.ac.uk " Read Daniel's experience of advising GALENOS here: www.galenos.org.uk/blog-news/re...
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GALENOS @galenos.bsky.social · 20/08/2025
If you're going to the SSPE Symposium in Basel this month don't miss the presentation from @thomytonia.bsky.social on how GALENOS uses triangulation to produce the best research outcomes. #researchmatters #mentalhealth
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GALENOS @galenos.bsky.social · 15/08/2025
"For me, co-production means, 'Hey, I have an idea, and I’m empowered to share it to improve this cause'.” Glebe member Promise Adetoro shares why it's essential to involve people with lived and living experience in research. 👉https://www.galenos.org.uk/blog-news/influence-of-coproduction
A picture of a young woman with dreadlocks next to a quote which reads: "This co-production exceeded all my expectations. It’s the most involved I’ve ever been in anything. Normally, our input would just be quotes in a paper. This time, we helped shape the direction.”
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GALENOS @galenos.bsky.social · 27/06/2025
"For years I didn’t feel included in conversations about mental health especially when it came to research. So when I was invited to contribute to the GALENOS project, it wasn’t just another meeting it was a moment of recognition." Read GLEAB member Clara's story: www.galenos.org.uk/blog-news/pa...
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GALENOS @galenos.bsky.social · 19/06/2025
What happens when lived experience meets mental health research? GLEAB member Kelvin Opiepie shares a powerful reflection on identity, inclusion, and the value of diverse voices in shaping better mental health outcomes. Read more: www.galenos.org.uk/blog-news/be... #MentalHealth
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GALENOS @galenos.bsky.social · 01/05/2025
"In complex projects like GALENOS that face the challenge of how to deliver meaningful lived experience engagement, we must get used to discomfort. If you're experiencing this, it likely indicates that you're on the right path." - Emily Wheeler #bna2025 www.galenos.org.uk/blog-news/re...
Emily Wheeler and Niall Boyce sitting on stage at the British Neuroscience Conference in front of a large screen with the conference logo.
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GALENOS @galenos.bsky.social · 10/04/2025
"One thing co-production is not - is having one voice louder than the other. It's not about putting lived experience above research or research above lived experience. If one voice dominates, you lose the very essence of what co-production is meant to achieve." 2/3
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GALENOS @galenos.bsky.social · 10/04/2025
"Co-production can be complex because it means different things in different contexts." GALENOS Glebe chair Tate Kambeu recently spoke at the International Association of Youth Mental Health conference in Vancouver. 🧵1/3
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GALENOS @galenos.bsky.social · 03/04/2025
Want to know more about GALENOS's methodology? Dr Virginia Chiocchia shared this recently: “I was really pleased to showcase the methodology of the GALENOS living systematic reviews and triangulation process at the Female Empowerment in Life Science (FELS) Research Day at the University of Bern”.
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GALENOS @galenos.bsky.social · 06/03/2025
GALENOS uses AI to analyse over 250 million scholarly articles, identifying trending topics in mental health research, particularly in anxiety, depression, and psychosis. This technique can help identify trends in research & not just in mental health. Find out more: galenos.org.uk/blog-news/ho...
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GALENOS @galenos.bsky.social · 06/02/2025
By making the best use of existing data, our hope is that GALENOS will accelerate progress in developing a better understanding and new treatments for the prevention and early intervention of anxiety, depression, and psychosis. More here: galenos.org.uk/news/galenos... 6/6 - ENDS
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GALENOS @galenos.bsky.social · 06/02/2025
By creating datasets and insights that are easy to navigate in an online resource, this project will accelerate research into effective new interventions and solutions for the 1 in 4 of us impacted by mental illness. Find out more here: galenos.org.uk 5/6
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GALENOS @galenos.bsky.social · 06/02/2025
GALENOS aims to tackle the slow progress in developing new treatments by making it easier for mental health researchers to access the scientific literature which gets published every day. Read more in the BMJ article here: mentalhealth.bmj.com/content/26/1... 4/6
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GALENOS @galenos.bsky.social · 06/02/2025
1 in 4 of us live with a mental illness. #Anxiety #Depression and #Psychosis are three of the most common #MentalHealth conditions which can devastate lives. Despite this, research into treating these conditions has been historically underfunded and progress has been slow. 3/6
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GALENOS @galenos.bsky.social · 06/02/2025
We are funded by @wellcometrust.bsky.social & are partnered with 17 leading #mentalhealth organisations including: 🟡 @mqmentalhealth.bsky.social 🟡 @ox.ac.uk 🟡 @edinburgh-uni.bsky.social 🟡 @monashuniversity.bsky.social 🟡 @suhealthsci.bsky.social 🟡 @unibern.bsky.social 🟡 @ucm.es 2/6
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GALENOS @galenos.bsky.social · 06/02/2025
GALENOS is a resource curated by a global community of academics & experts by experience who are passionate about facilitating research that can truly make a difference to peoples lives. 1/6
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