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DNA sequences derived from ancient samples provide insights into human history, paleoenvironments, and evolutionary biology. Advances in laboratory techniques and computational tools have established ...

The Vienna Doctoral School of Ecology and Evolution is dedicated to educating students to advance our understanding of the ecology and evolution of extant and ancestral organisms, populations, and communities. In Ecology, the focus is on uncovering the mechanistic and evolutionary drivers of patterns and processes across biological scales, from gene regulation to ecosystem structure and function, including the role of communities in biogeochemical cycles and their adaptive responses to environmental change. In Evolution, we investigate the processes shaping changes in organization and dynamics of organisms, populations, and species at molecular, developmental, morphological, and physiological levels.

De novo assembly of ancient metagenomic datasets is a challenging task. Ultra-short fragment size and characteristic postmortem damage patterns of sequenced ancient DNA molecules leave current tools i...

Bioinformatician, Department of Organismal Biology, Uppsala University

AbstractMotivation. DNA damage patterns, such as increased frequencies of C→T and G→A substitutions at fragment ends, are widely used in ancient DNA studie

Motivation DNA damage patterns, such as increased frequencies of C>T and G>A substitutions at fragment ends, are widely used in ancient DNA studies to assess authenticity and detect contamination. In ...