So excited to share the last contribution of our lab in collaboration with Prof. Ghosh’s lab in @columbiauniversity.bsky.social . Another #lncRNA harboring a genetic variant that contributes to risk to develop #IBD. Great collaborative work!
www.sciencedirect.com/science/arti...
sciencedirect.com
An inflammatory bowel disease-linked lncRNA suppresses transcription factor T-BET expression in T cells to limit intestinal inflammation
Among the tens of thousands of annotated long noncoding RNAs (lncRNAs) in the human genome, only a small fraction have been functionally characterized…