The noncanonical functions of PKM2 drive pathogenic T cell function in patients with MS.

Systematic annotation of noncanonical ORFs illuminates the “dark” immunopeptidome.

The pathogenesis of type 1 diabetes, particularly at autoantibody-positive preclinical stages, remains poorly understood, in part due to limited sample availability. Here we show imaging mass cytometry data of pancreas samples from 88 organ donors, including 28 single and 10 multiple autoantibody-po …

Cell-based immunotherapies

Osteoclast-mediated skull bone channel remodeling influences meningeal immune infiltration upon challenge.