Reposted by Francesco MarchettiCarole Yauk @caroleyauk.bsky.social · 16/04/2025The Council of the Town of Parry Sound unanimously resolved to support the national call for stronger federal support for inclusive research that reflects the diversity of Canadian communities. Thank you to the Mayor and Council for discussing and supporting Canadian research! 211
Francesco Marchetti @fmarchetti.bsky.social · 04/04/2025A call to open-minded Canadians to sign this petition. What is happening in the United States MUST NOT happen here 010
Francesco Marchetti @fmarchetti.bsky.social · 18/02/2025Out today in Biology of Reproduction. First application of duplex sequencing to detect chemically induced mutations in germ cells. academic.oup.com/biolreprod/a...academic.oup.comDuplex sequencing identifies unique characteristics of ENU-induced mutations in male mouse germ cellsAbstract. Germ cell mutagenicity testing is increasingly required for chemical risk assessment. Duplex Sequencing (DS) is rapidly gaining acceptance as a m 030
Francesco Marchetti @fmarchetti.bsky.social · 04/02/2025If you are a young scientist who has never attended an EMGS meeting, you have missed a chance to discover an amazing, welcoming community of scientists who makes a point to help build careers. I owe mine to the EMGS. 096
Francesco Marchetti @fmarchetti.bsky.social · 03/02/2025First accepted manuscript of the year ☺️ First study to report on the use of Duplex Sequencing to detect chemically induced mutations in mouse male germ cells Another exciting project from the wonderful collaboration with @caroleyauk.bsky.social 121
Francesco Marchetti @fmarchetti.bsky.social · 01/02/2025Just found out that Larry Thompson passed away. He was one of the stars of the Biology program at Lawrence Livermore National Lab. His work with Chinese hamster cells led to the discovery of several DNA repair genes critical for genomic stability. Doi.org/10.1016/j.dnarep.2025.103813doi.orgRedirecting 010
Francesco Marchetti @fmarchetti.bsky.social · 19/01/2025The journal right now is getting about 120-140 manuscripts a year and the editorial board is quite helpful. I would say an hr a day. 010
Francesco Marchetti @fmarchetti.bsky.social · 12/01/2025Nice study out of Stephen Lloyd’s lab. Using ultra-accurate duplex sequencing, this study reveals how deficiencies in DNA repair increases aflatoxin B1-induced mutagenesis in mice. #science aacrjournals.org/mcr/article/...aacrjournals.orgThe Distinct Roles of NEIL1 and XPA in Limiting Aflatoxin B1–Induced Mutagenesis in MiceAbstract. Dietary exposure to aflatoxin B1 (AFB1) is a risk factor for the development of hepatocellular carcinomas. Following metabolic activation, AFB1 reacts with guanines to form covalent DNA addu... 020
Francesco Marchetti @fmarchetti.bsky.social · 12/01/2025Hi, Research Scientist at Health Canada. Looking to connect with other scientists 030
Francesco Marchetti @fmarchetti.bsky.social · 10/01/2025I had the honour to serve as Editor-in-Chief of Environmental and Molecular Mutagenesis in 2012-2016 and it is an experience that I have enjoyed and never regretted. I encourage all scientists with an interest in genomics and mutagenesis to really put your hat on the table and apply for it. 173
Francesco Marchetti @fmarchetti.bsky.social · 08/01/2025If it were not for lead poisoning, we would all be speaking latin today ☺️ www.science.org/content/arti...science.orgAncient Romans likely breathed lead pollutionIce cores show ancient silver production produced lead levels high enough to lower some people’s IQ 030
Francesco Marchetti @fmarchetti.bsky.social · 04/01/2025After leaving the bird, I gave Threads a chance to be my source of news about science, culture and politics. I had hopes, but it is now just Facebook with strangers. 2025 is the year I am giving Bluesky a chance. 060
