Sign in

Fondazione Gianni Bonadonna

@fgbonadonna.bsky.social
115 followers 529 following 96 posts

FGB promotes therapeutic innovation from the earliest phases of research and the education of new generations of physician-scientists in Oncology

PostsRepliesMedia
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 05/10/2026
In a new study, thymic health emerged as a previously unrecognized determinant of immunotherapy efficacy in many tumours, with potential implications for patient stratification, treatment timing and the development of immune-rejuvenating strategies fondazionebonadonna.org/en/pembroliz...
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 28/09/2026
Adding belzutifan to adjuvant pembrolizumab improves disease-free survival but increases adverse events in resected clear-cell renal cell carcinoma at increased risk for recurrence fondazionebonadonna.org/en/pembroliz... #FondazioneBonadonna #Oncology #CancerResearch
fondazionebonadonna.org
Pembrolizumab and belzutifan in high risk renal cell carcinoma
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 22/09/2026
Results from BREAKWATER Cohort 3 trial show clinically meaningful improvements in objective response rate and progression-free survival for encorafenib, cetuximab plus FOLFIRI in BRAF V600E-mutant colorectal cancer fondazionebonadonna.org/en/encorafen... #FondazioneBonadonna #CancerResearch
fondazionebonadonna.org
Encorafenib, cetuximab and FOLFIRI in metastatic colorectal cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 14/09/2026
The oral RAS(ON) multiselective inhibitor daraxonrasib shows a significantly longer overall survival and progression-free survival in patients with previously treated metastatic pancreatic ductal adenocarcinoma www.fondazionebonadonna.eu/en/daraxonra... #FondazioneBonadonna #Oncology #CancerResearch
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 07/09/2026
ROSELLA trial shows a benefit in overall survival with relacorilant added to nab-paclitaxel in patients with platinum-resistant ovarian cancer www.fondazionebonadonna.eu/en/relacoril... #FondazioneBonadonna #Oncology #CancerResearch
fondazionebonadonna.eu
Relacorilant plus nab-paclitaxel in platinum-resistant ovarian cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 31/08/2026
A new phase 1b trial shows a manageable safety profile and promising antitumor activity for cibisatamab plus FAP-4-1BB ligand in microsatellite-stable metastatic colorectal cancer www.fondazionebonadonna.org/en/cibisatam... #FondazioneBonadonna #Oncology #CancerResearch
fondazionebonadonna.org
Cibisatamab and FAP-4-1BBL in microsatellite-stable metastatic colorectal cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 24/08/2026
Pembrolizumab plus weekly paclitaxel, with or without bevacizumab, improved progression-free survival and overall survival in patients with platinum-resistant recurrent ovarian cancer www.fondazionebonadonna.eu/en/pembroliz... #FondazioneBonadonna #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.eu
Pembrolizumab plus weekly paclitaxel in platinum-resistant recurrent ovarian cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 04/08/2026
“We are pleased to share the opening of the call for the "Physician Scientist 2026" program promoted by Fondazione AIRC and Fondazione Cariplo, in collaboration with SEMM and the University of Milan. Applications can be submitted at: semm.it/application-...
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 03/08/2026
In the phase 3 CheckMate 214 trial, nivolumab plus ipilimumab showed a substantial benefit versus sunitinib in patients with previously untreated advanced renal carcinoma www.fondazionebonadonna.eu/en/nivolumab... @mauriziocallari.bsky.social
fondazionebonadonna.eu
Nivolumab plus ipilimumab as first-line therapy of advanced renal cell carcinoma
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 27/07/2026
In a paper co-authored by a winner of 2025 Gianni Bonadonna Fellowship, the potential benefit of in vivo co-selection of gene-engineered cells for niche clearance in hemopoietic stem/progenitor cells transplantation www.fondazionebonadonna.eu/en/a-new-suc... #FondazioneBonadonna #CancerResearch
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 20/07/2026
In patients with previously untreated advanced triple-negative breast cancer, the combination of sacituzumab govitecan led to significantly longer progression-free survival fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #CancerResearch @mauriziocallari.bsky.social
001
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 14/07/2026
The phase 3 RELATIVITY-098 trial shows no added benefit with nivolumab plus relatlinib compared to nivolumab alone in stage III/IV melanoma www.fondazionebonadonna.eu/en/adjuvant-... #FondazioneBonadonna #Oncology #CancerResearch
fondazionebonadonna.eu
Adjuvant nivolumab plus relatlimab in stage III/IV melanoma
Fondazione Gianni Bonadonna
010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 06/07/2026
A phase1/2 trial shows promising antitumor activity for the next-generation tyrosine kinase inhibitor repotrectinib in NTRK fusion-positive advanced solid tumors www.fondazionebonadonna.eu/en/repotrect... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.eu
Repotrectinib in NTRK fusion-positive advanced solid tumors
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 29/06/2026
In a phase II trial, cabozantinib plus temozolomide showed a meaningful clinical benefit for patients with unresectable or metastatic leiomyosarcoma www.fondazionebonadonna.eu/en/cabozanti... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 22/06/2026
A cycle of neoadjuvant immune checkpoint blockade before chemoradiation improves response to standard therapy in cervical squamous carcinoma www.fondazionebonadonna.eu/en/neoadjuva... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.eu
Neoadjuvant immunotherapy before chemoradiation in cervical squamous carcinoma
Fondazione Gianni Bonadonna
010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 15/06/2026
An ultra-low dose of nivolumab significantly improves overall survival in heavily pretreated advanced solid tumors, with fewer toxicities and better quality of life. www.fondazionebonadonna.eu/en/efficacy-... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.eu
Efficacy of an ultra-low dose of immunotherapy in relapsed refrfactory solid tumors
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 08/06/2026
La borsa di studio intitolata a Gianni Bonadonna nel racconto di chi l’ha vissuta. www.fondazionebonadonna.eu/la-borsa-di-... #FondazioneBonadonna #PradaGroup #Esoncology #CancerResearch #fellowship
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 03/06/2026
The applications for the 2026 edition of the "Gianni Bonadonna Fellowship" are now open. Download the full Call for Proposals and Application Guidelines online. Read more www.fondazionebonadonna.eu/en/fellowshi...
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 28/05/2026
Transcriptomics boosts response prediction in triple-negative breast cancer. New data from the NeoTRIPaPDL1 phase III trial. Read more: fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #Oncology #CancerResearch
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 25/05/2026
Tucatinib plus trastuzumab showed clinically meaningful efficacy and favorable safety in chemotherapy refractory, HER2+, RAS wild type metastatic colorectal cancer fondazionebonadonna.org/en/tucatinib... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Tucatinib plus trastuzumab in chemotherapy-refractory metastatic colorectal cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 18/05/2026
Promising efficacy for a PARP inhibitor rechallenge with bevacizumab in patients with ovarian cancer previously treated with a PARP inhibitor, especially if responsive to prior platinum-base chemotherapy fondazionebonadonna.org/en/parp-inhi... #FondazioneBonadonna #Oncology #CancerResearch
fondazionebonadonna.org
PARP inhibitor rechallenge plus bevacizumab in ovarian cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 13/05/2026
Findings from the MASAI Swedish study show consistently more favorable outcomes with AI-supported mammography screening versus standard double reading. fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #Oncology #CancerResearch
011
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 11/05/2026
The sixth edition of the post-doctoral Fellowship Program promoted by Fondazione Bonadonna, with Prada Group supporting partner and in collaboration with the European School of Oncology is about to begin. Applications open from June 3rd until July 21st 2026 fondazionebonadonna.org/en/a-new-edi...
fondazionebonadonna.org
A new edition for the international fellowships in honor of Gianni Bonadonna
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 04/05/2026
Results from the FMT-LUMINate trial show a positive clinical activity for fecal microbiota transplantation plus immunotherapy in non small cell lung cancer and melanoma fondazionebonadonna.org/en/fecal-mic... #FondazioneBonadonna #CancerResearch #Oncology @mauriziocallari.bsky.social
fondazionebonadonna.org
Fecal microbiota transplantation plus immunotherapy in non small cell lung cancer and melanoma
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 27/04/2026
In patients with locally advanced head and neck squamous cell carcinoma with limited treatment options, intratumoral NBTXR3 followed by radiotherapy was feasible and had a preliminary signal in efficacy fondazionebonadonna.org/en/the-use-o... #FondazioneBonadonna #Oncology #CancerResearch
fondazionebonadonna.org
The use of intratumoral radioenhancer nanoparticle NBTXR3 in head and neck cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 20/04/2026
The final analysis of the phase 2 HERIZON-BTC-01 trial show a clinically meaningful benefit for zanidatamab in patients with treatment refractory HER2-positive biliary tract cancer fondazionebonadonna.org/en/zanidatam... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Zanidatamab in HER2- positive metastatic biliary tract cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 13/04/2026
Preoperative PAXG significantly improved event-free survival compared to mFOLFRINOX in patients with resectable pancreatic ductal adenocarcinoma fondazionebonadonna.org/en/a-compari... #FondazioneBonadonna #Oncology #CancerResearch
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 08/04/2026
In HER2+ breast cancer patients a neoadjuvant therapy with a selected taxane plus trastuzumab but without carboplatin leads to similar benefits in pathological complete response and improves tolerability fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #CancerResearch #Oncology
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 30/03/2026
The PATINA study coordinated in Italy by Fondazione Michelangelo, shows that adding palbociclib to standard therapy improves progression-free survival in hormone receptor-positive and HER2-positive metastatic breast cancer patients fondazionemichelangelo.org/news-update/... #BreastCancer #Oncology
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 23/03/2026
Results from the phase 2 PRADO trial show favorable 5-years outcomes in overall survival with adjuvant ipilimumab plus nivolumab in stage III macroscopic melanoma fondazionebonadonna.org/en/neoadjuva... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Neoadjuvant ipilimumab plus nivolumab in melanoma
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 19/03/2026
Clinical benefits on disease-free survival and overall survival with the addition of carboplatin to adjuvant epirubicin/cyclophosphamide followed by taxanes in early-stage triple-negative breast cancer fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #Oncology #CancerResearch
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 16/03/2026
Adding the bispecific anti-HER2 antibody anbenitamab to chemotherapy improved progression-free survival and overall survival in previously treated HER2-positive gastric cancer fondazionebonadonna.org/en/anbenitam... #FondazioneBonadonna #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Anbenitamab in previously treated HER2-positive gastric cancer
Fondazione Gianni Bonadonna
001
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 09/03/2026
Neoadjuvant intralesional darumon, a combination of two fibronectin-targeting immunocytokines, improved recurrence-free survival in patients with locally advanced melanoma fondazionebonadonna.org/en/targeted-... #FondazioneBonadonna #CancerResearch #Oncology @mauriziocallari.bsky.social
fondazionebonadonna.org
Targeted immunocytokines as a neoadjuvant treatment in melanoma
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 02/03/2026
Addition of camrelizumab to neoadjuvant chemotherapy significantly improves pathological complete response rate in early or locally advanced triple-negative breast cancer fondazionebonadonna.org/en/neoadjuva... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Neoadjuvant camrelizumab plus chemotherapy in triple-negative breast cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 24/02/2026
Camrelizumab plus chemotherapy, compared to chemoradiotherapy, is a safe an effective neoadjuvant strategy in resectable esophageal squamous cell carcinoma fondazionebonadonna.org/en/camrelizu... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Camrelizumab plus chemotherapy as neoadjuvant therapy in resectable esophageal squamous cell carcinoma
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 18/02/2026
Addition of carboplatin to sequential taxane-anthracycline neoadjuvant therapy increased overall survival in premenopausal women with triple-negative breast cancer fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #Oncology #CancerResearch @mauriziocallari.bsky.social
110
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 16/02/2026
A combination of nivolumab and ipilimumab is associated with a high rate of durable responses in mismatch repair–deficient/microsatellite instability–high non colorectal cancers fondazionebonadonna.org/en/a-combina... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 09/02/2026
A promising clinical activity for the novel antibody-drug conjugate patritumab deruxtecan in non-small-cell lung cancer patients with active brain metastases fondazionebonadonna.org/en/efficacy-... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Efficacy of patritumab deruxtecan on brain metastases in non-small-cell lung cancer carcinoma
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 04/02/2026
On the occasion of World Cancer Day 2026, #FGB, with the support of the Prada Group and in collaboration with #ESO, announces the 3 winners of the fifth edition of the Fellowship named after Gianni Bonadonna. Press Release fondazionebonadonna.org/wp-content/u...) #FondazioneBonadonna #PradaGroup
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 28/01/2026
A new phase 3 trial shows the non-inferiority of three versus six months of adjuvant chemotherapy with oxaliplatin and a fluoropyrimidine in colorectal cancer fondazionebonadonna.org/en/three-ver... #FondazioneBonadonna #Oncology #CancerResearch
fondazionebonadonna.org
Three versus six months of adjuvant chemotherapy in colorectal cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 19/01/2026
In a phase 1 trial, universal base-edited CAR7 T cells induced remission in relapsed or refractory acute lymphoblastic leukemia allowing a successful stem-cell translplantation in most patients fondazionebonadonna.org/en/universal... #FondazioneBonadonna #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Universal base-edited CAR7 T cells in acute lymphoblastic leukemia
Fondazione Gianni Bonadonna
010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 12/01/2026
Sacituzumab govitecan as first-line therapy showed a significantly longer progression-free survival than chemotherapy in patients with advanced triple-negative breast cancer fondazionebonadonna.org/en/sacituzum... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Sacituzumab govitecan in advanced triple-negative breast cancer
Fondazione Gianni Bonadonna
010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 05/01/2026
Results from lidERA trial show a significant improvement in disease-free survival with the novel SERD giredestrant in HR+/HER2- early stage breast cancer fondazionebonadonna.org/en/disease-f... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Disease-free survival improvement with adjuvant giredestrant in breast cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 29/12/2025
In patients with muscle-invasive bladder cancer, ctDNA-guided adjuvant therapy with atezolizumab improved disease-free survival and overall survival fondazionebonadonna.org/en/a-ctdna-g... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
A ctDNA-guided atezolizumab therapy in bladder cancer
Fondazione Gianni Bonadonna
010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 23/12/2025
Results from lidERA trial show a significant improvement in disease-free survival with the novel SERD giredestrant in HR+/HER2- early stage breast cancer fondazionebonadonna.org/en/capivaser... #FondazioneGianniBonadonna #CancerResearch #Oncology @mauriziocallari.bsky.social
fondazionebonadonna.org
Capivasertib plus abiraterone in metastatic hormone-sensitive prostate cancer
Fondazione Gianni Bonadonna
000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 15/12/2025
In a phase 3 trial the addition of neoadjuvant and adjuvant pembrolizumab to standard care improved clinical outcome in patients with advanced head and neck cancer fondazionebonadonna.org/en/neoadjuva... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Neoadjuvant and adjuvant pembrolizumab in head and neck cancer
Fondazione Gianni Bonadonna
010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 10/12/2025
Adjiuvant abemaciclib added to endocrine therapy improves overall survival in patients with HR+/HER2- high risk early breast cancer fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social
010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 01/12/2025
Results from TUXEDO-3 phase 2 trial show a promising clinical activity for the novel antibody-drug conjugate patritumab deruxtecan in breast cancer patients with acrive brain metastases fondazionebonadonna.org/en/patrituma... #FondazioneBonadonna #CancerResearch @mauriziocallari.bsky.social
fondazionebonadonna.org
Patritumab deruxtecan activity in breast cancer patients with brain metastases
Fondazione Gianni Bonadonna
010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 24/11/2025
A new study identifies 7 tumor microenvironment types and shows how they can shape therapeutic response, recurrence and metastases development in breast cancer fondazionebonadonna.org/en/the-relev... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social #Bianchini #Criscitiello
fondazionebonadonna.org
The relevance of tumor microenvironment for clinical outcomes in breast cancer
Fondazione Gianni Bonadonna
042
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 17/11/2025
A lot of advances have emerged from the Joint International Conference 2025 Innovation in Oncology organized by FGB with Prada Group supporting partner, by Fondazione Michelangelo and by European School of Oncology fondazionebonadonna.org/en/from-new-... #FondazioneGianniBonadonna #CancerResearch
020