Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 05/10/2026In a new study, thymic health emerged as a previously unrecognized determinant of immunotherapy efficacy in many tumours, with potential implications for patient stratification, treatment timing and the development of immune-rejuvenating strategies fondazionebonadonna.org/en/pembroliz... 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 28/09/2026Adding belzutifan to adjuvant pembrolizumab improves disease-free survival but increases adverse events in resected clear-cell renal cell carcinoma at increased risk for recurrence fondazionebonadonna.org/en/pembroliz... #FondazioneBonadonna #Oncology #CancerResearchfondazionebonadonna.orgPembrolizumab and belzutifan in high risk renal cell carcinomaFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 22/09/2026Results from BREAKWATER Cohort 3 trial show clinically meaningful improvements in objective response rate and progression-free survival for encorafenib, cetuximab plus FOLFIRI in BRAF V600E-mutant colorectal cancer fondazionebonadonna.org/en/encorafen... #FondazioneBonadonna #CancerResearchfondazionebonadonna.orgEncorafenib, cetuximab and FOLFIRI in metastatic colorectal cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 14/09/2026The oral RAS(ON) multiselective inhibitor daraxonrasib shows a significantly longer overall survival and progression-free survival in patients with previously treated metastatic pancreatic ductal adenocarcinoma www.fondazionebonadonna.eu/en/daraxonra... #FondazioneBonadonna #Oncology #CancerResearch 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 07/09/2026ROSELLA trial shows a benefit in overall survival with relacorilant added to nab-paclitaxel in patients with platinum-resistant ovarian cancer www.fondazionebonadonna.eu/en/relacoril... #FondazioneBonadonna #Oncology #CancerResearchfondazionebonadonna.euRelacorilant plus nab-paclitaxel in platinum-resistant ovarian cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 31/08/2026A new phase 1b trial shows a manageable safety profile and promising antitumor activity for cibisatamab plus FAP-4-1BB ligand in microsatellite-stable metastatic colorectal cancer www.fondazionebonadonna.org/en/cibisatam... #FondazioneBonadonna #Oncology #CancerResearchfondazionebonadonna.orgCibisatamab and FAP-4-1BBL in microsatellite-stable metastatic colorectal cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 24/08/2026Pembrolizumab plus weekly paclitaxel, with or without bevacizumab, improved progression-free survival and overall survival in patients with platinum-resistant recurrent ovarian cancer www.fondazionebonadonna.eu/en/pembroliz... #FondazioneBonadonna #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.euPembrolizumab plus weekly paclitaxel in platinum-resistant recurrent ovarian cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 04/08/2026“We are pleased to share the opening of the call for the "Physician Scientist 2026" program promoted by Fondazione AIRC and Fondazione Cariplo, in collaboration with SEMM and the University of Milan. Applications can be submitted at: semm.it/application-... 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 03/08/2026In the phase 3 CheckMate 214 trial, nivolumab plus ipilimumab showed a substantial benefit versus sunitinib in patients with previously untreated advanced renal carcinoma www.fondazionebonadonna.eu/en/nivolumab... @mauriziocallari.bsky.socialfondazionebonadonna.euNivolumab plus ipilimumab as first-line therapy of advanced renal cell carcinomaFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 27/07/2026In a paper co-authored by a winner of 2025 Gianni Bonadonna Fellowship, the potential benefit of in vivo co-selection of gene-engineered cells for niche clearance in hemopoietic stem/progenitor cells transplantation www.fondazionebonadonna.eu/en/a-new-suc... #FondazioneBonadonna #CancerResearch 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 20/07/2026In patients with previously untreated advanced triple-negative breast cancer, the combination of sacituzumab govitecan led to significantly longer progression-free survival fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #CancerResearch @mauriziocallari.bsky.social 001
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 14/07/2026The phase 3 RELATIVITY-098 trial shows no added benefit with nivolumab plus relatlinib compared to nivolumab alone in stage III/IV melanoma www.fondazionebonadonna.eu/en/adjuvant-... #FondazioneBonadonna #Oncology #CancerResearchfondazionebonadonna.euAdjuvant nivolumab plus relatlimab in stage III/IV melanomaFondazione Gianni Bonadonna 010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 06/07/2026A phase1/2 trial shows promising antitumor activity for the next-generation tyrosine kinase inhibitor repotrectinib in NTRK fusion-positive advanced solid tumors www.fondazionebonadonna.eu/en/repotrect... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.euRepotrectinib in NTRK fusion-positive advanced solid tumorsFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 29/06/2026In a phase II trial, cabozantinib plus temozolomide showed a meaningful clinical benefit for patients with unresectable or metastatic leiomyosarcoma www.fondazionebonadonna.eu/en/cabozanti... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 22/06/2026A cycle of neoadjuvant immune checkpoint blockade before chemoradiation improves response to standard therapy in cervical squamous carcinoma www.fondazionebonadonna.eu/en/neoadjuva... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.euNeoadjuvant immunotherapy before chemoradiation in cervical squamous carcinomaFondazione Gianni Bonadonna 010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 15/06/2026An ultra-low dose of nivolumab significantly improves overall survival in heavily pretreated advanced solid tumors, with fewer toxicities and better quality of life. www.fondazionebonadonna.eu/en/efficacy-... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.euEfficacy of an ultra-low dose of immunotherapy in relapsed refrfactory solid tumorsFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 08/06/2026La borsa di studio intitolata a Gianni Bonadonna nel racconto di chi l’ha vissuta. www.fondazionebonadonna.eu/la-borsa-di-... #FondazioneBonadonna #PradaGroup #Esoncology #CancerResearch #fellowship 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 03/06/2026The applications for the 2026 edition of the "Gianni Bonadonna Fellowship" are now open. Download the full Call for Proposals and Application Guidelines online. Read more www.fondazionebonadonna.eu/en/fellowshi... 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 28/05/2026Transcriptomics boosts response prediction in triple-negative breast cancer. New data from the NeoTRIPaPDL1 phase III trial. Read more: fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #Oncology #CancerResearch 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 25/05/2026Tucatinib plus trastuzumab showed clinically meaningful efficacy and favorable safety in chemotherapy refractory, HER2+, RAS wild type metastatic colorectal cancer fondazionebonadonna.org/en/tucatinib... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgTucatinib plus trastuzumab in chemotherapy-refractory metastatic colorectal cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 18/05/2026Promising efficacy for a PARP inhibitor rechallenge with bevacizumab in patients with ovarian cancer previously treated with a PARP inhibitor, especially if responsive to prior platinum-base chemotherapy fondazionebonadonna.org/en/parp-inhi... #FondazioneBonadonna #Oncology #CancerResearchfondazionebonadonna.orgPARP inhibitor rechallenge plus bevacizumab in ovarian cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 13/05/2026Findings from the MASAI Swedish study show consistently more favorable outcomes with AI-supported mammography screening versus standard double reading. fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #Oncology #CancerResearch 011
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 11/05/2026The sixth edition of the post-doctoral Fellowship Program promoted by Fondazione Bonadonna, with Prada Group supporting partner and in collaboration with the European School of Oncology is about to begin. Applications open from June 3rd until July 21st 2026 fondazionebonadonna.org/en/a-new-edi...fondazionebonadonna.orgA new edition for the international fellowships in honor of Gianni BonadonnaFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 04/05/2026Results from the FMT-LUMINate trial show a positive clinical activity for fecal microbiota transplantation plus immunotherapy in non small cell lung cancer and melanoma fondazionebonadonna.org/en/fecal-mic... #FondazioneBonadonna #CancerResearch #Oncology @mauriziocallari.bsky.socialfondazionebonadonna.orgFecal microbiota transplantation plus immunotherapy in non small cell lung cancer and melanomaFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 27/04/2026In patients with locally advanced head and neck squamous cell carcinoma with limited treatment options, intratumoral NBTXR3 followed by radiotherapy was feasible and had a preliminary signal in efficacy fondazionebonadonna.org/en/the-use-o... #FondazioneBonadonna #Oncology #CancerResearchfondazionebonadonna.orgThe use of intratumoral radioenhancer nanoparticle NBTXR3 in head and neck cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 20/04/2026The final analysis of the phase 2 HERIZON-BTC-01 trial show a clinically meaningful benefit for zanidatamab in patients with treatment refractory HER2-positive biliary tract cancer fondazionebonadonna.org/en/zanidatam... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgZanidatamab in HER2- positive metastatic biliary tract cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 13/04/2026Preoperative PAXG significantly improved event-free survival compared to mFOLFRINOX in patients with resectable pancreatic ductal adenocarcinoma fondazionebonadonna.org/en/a-compari... #FondazioneBonadonna #Oncology #CancerResearch 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 08/04/2026In HER2+ breast cancer patients a neoadjuvant therapy with a selected taxane plus trastuzumab but without carboplatin leads to similar benefits in pathological complete response and improves tolerability fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #CancerResearch #Oncology 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 30/03/2026The PATINA study coordinated in Italy by Fondazione Michelangelo, shows that adding palbociclib to standard therapy improves progression-free survival in hormone receptor-positive and HER2-positive metastatic breast cancer patients fondazionemichelangelo.org/news-update/... #BreastCancer #Oncology 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 23/03/2026Results from the phase 2 PRADO trial show favorable 5-years outcomes in overall survival with adjuvant ipilimumab plus nivolumab in stage III macroscopic melanoma fondazionebonadonna.org/en/neoadjuva... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgNeoadjuvant ipilimumab plus nivolumab in melanomaFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 19/03/2026Clinical benefits on disease-free survival and overall survival with the addition of carboplatin to adjuvant epirubicin/cyclophosphamide followed by taxanes in early-stage triple-negative breast cancer fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #Oncology #CancerResearch 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 16/03/2026Adding the bispecific anti-HER2 antibody anbenitamab to chemotherapy improved progression-free survival and overall survival in previously treated HER2-positive gastric cancer fondazionebonadonna.org/en/anbenitam... #FondazioneBonadonna #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgAnbenitamab in previously treated HER2-positive gastric cancerFondazione Gianni Bonadonna 001
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 09/03/2026Neoadjuvant intralesional darumon, a combination of two fibronectin-targeting immunocytokines, improved recurrence-free survival in patients with locally advanced melanoma fondazionebonadonna.org/en/targeted-... #FondazioneBonadonna #CancerResearch #Oncology @mauriziocallari.bsky.socialfondazionebonadonna.orgTargeted immunocytokines as a neoadjuvant treatment in melanomaFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 02/03/2026Addition of camrelizumab to neoadjuvant chemotherapy significantly improves pathological complete response rate in early or locally advanced triple-negative breast cancer fondazionebonadonna.org/en/neoadjuva... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgNeoadjuvant camrelizumab plus chemotherapy in triple-negative breast cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 24/02/2026Camrelizumab plus chemotherapy, compared to chemoradiotherapy, is a safe an effective neoadjuvant strategy in resectable esophageal squamous cell carcinoma fondazionebonadonna.org/en/camrelizu... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgCamrelizumab plus chemotherapy as neoadjuvant therapy in resectable esophageal squamous cell carcinomaFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 18/02/2026Addition of carboplatin to sequential taxane-anthracycline neoadjuvant therapy increased overall survival in premenopausal women with triple-negative breast cancer fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #Oncology #CancerResearch @mauriziocallari.bsky.social 110
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 16/02/2026A combination of nivolumab and ipilimumab is associated with a high rate of durable responses in mismatch repair–deficient/microsatellite instability–high non colorectal cancers fondazionebonadonna.org/en/a-combina... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 09/02/2026A promising clinical activity for the novel antibody-drug conjugate patritumab deruxtecan in non-small-cell lung cancer patients with active brain metastases fondazionebonadonna.org/en/efficacy-... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgEfficacy of patritumab deruxtecan on brain metastases in non-small-cell lung cancer carcinomaFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 04/02/2026On the occasion of World Cancer Day 2026, #FGB, with the support of the Prada Group and in collaboration with #ESO, announces the 3 winners of the fifth edition of the Fellowship named after Gianni Bonadonna. Press Release fondazionebonadonna.org/wp-content/u...) #FondazioneBonadonna #PradaGroup 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 28/01/2026A new phase 3 trial shows the non-inferiority of three versus six months of adjuvant chemotherapy with oxaliplatin and a fluoropyrimidine in colorectal cancer fondazionebonadonna.org/en/three-ver... #FondazioneBonadonna #Oncology #CancerResearchfondazionebonadonna.orgThree versus six months of adjuvant chemotherapy in colorectal cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 19/01/2026In a phase 1 trial, universal base-edited CAR7 T cells induced remission in relapsed or refractory acute lymphoblastic leukemia allowing a successful stem-cell translplantation in most patients fondazionebonadonna.org/en/universal... #FondazioneBonadonna #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgUniversal base-edited CAR7 T cells in acute lymphoblastic leukemiaFondazione Gianni Bonadonna 010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 12/01/2026Sacituzumab govitecan as first-line therapy showed a significantly longer progression-free survival than chemotherapy in patients with advanced triple-negative breast cancer fondazionebonadonna.org/en/sacituzum... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgSacituzumab govitecan in advanced triple-negative breast cancerFondazione Gianni Bonadonna 010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 05/01/2026Results from lidERA trial show a significant improvement in disease-free survival with the novel SERD giredestrant in HR+/HER2- early stage breast cancer fondazionebonadonna.org/en/disease-f... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgDisease-free survival improvement with adjuvant giredestrant in breast cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 29/12/2025In patients with muscle-invasive bladder cancer, ctDNA-guided adjuvant therapy with atezolizumab improved disease-free survival and overall survival fondazionebonadonna.org/en/a-ctdna-g... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgA ctDNA-guided atezolizumab therapy in bladder cancerFondazione Gianni Bonadonna 010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 23/12/2025Results from lidERA trial show a significant improvement in disease-free survival with the novel SERD giredestrant in HR+/HER2- early stage breast cancer fondazionebonadonna.org/en/capivaser... #FondazioneGianniBonadonna #CancerResearch #Oncology @mauriziocallari.bsky.socialfondazionebonadonna.orgCapivasertib plus abiraterone in metastatic hormone-sensitive prostate cancerFondazione Gianni Bonadonna 000
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 15/12/2025In a phase 3 trial the addition of neoadjuvant and adjuvant pembrolizumab to standard care improved clinical outcome in patients with advanced head and neck cancer fondazionebonadonna.org/en/neoadjuva... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgNeoadjuvant and adjuvant pembrolizumab in head and neck cancerFondazione Gianni Bonadonna 010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 10/12/2025Adjiuvant abemaciclib added to endocrine therapy improves overall survival in patients with HR+/HER2- high risk early breast cancer fondazionemichelangelo.org/news-update/... #FondazioneMichelangelo #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social 010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 01/12/2025Results from TUXEDO-3 phase 2 trial show a promising clinical activity for the novel antibody-drug conjugate patritumab deruxtecan in breast cancer patients with acrive brain metastases fondazionebonadonna.org/en/patrituma... #FondazioneBonadonna #CancerResearch @mauriziocallari.bsky.socialfondazionebonadonna.orgPatritumab deruxtecan activity in breast cancer patients with brain metastasesFondazione Gianni Bonadonna 010
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 24/11/2025A new study identifies 7 tumor microenvironment types and shows how they can shape therapeutic response, recurrence and metastases development in breast cancer fondazionebonadonna.org/en/the-relev... #FondazioneBonadonna #Oncology #CancerResearch @mauriziocallari.bsky.social #Bianchini #Criscitiellofondazionebonadonna.orgThe relevance of tumor microenvironment for clinical outcomes in breast cancerFondazione Gianni Bonadonna 042
Fondazione Gianni Bonadonna @fgbonadonna.bsky.social · 17/11/2025A lot of advances have emerged from the Joint International Conference 2025 Innovation in Oncology organized by FGB with Prada Group supporting partner, by Fondazione Michelangelo and by European School of Oncology fondazionebonadonna.org/en/from-new-... #FondazioneGianniBonadonna #CancerResearch 020