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Reposted by Fanohinjanaharinirina Rasoamalala

Antoine Brault @abrault.bsky.social · 13/06/2025

Led by @fanohi.bsky.social, and co-supervised by @scauchemez.bsky.social, this study is the result of a fruitful collaboration between Institut Pasteur Madagascar and @pasteur.fr.

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Reposted by Fanohinjanaharinirina Rasoamalala

Antoine Brault @abrault.bsky.social · 13/06/2025

Finally, we evaluated intervention strategies and found that targeting both rats and their fleas at the start of the epidemic season (July–Sep) was the most effective way for reducing human plague cases. This proactive strategy contrasts with the reactive measures currently used in Madagascar.

Impact of the control of rat and flea populations on the number of human plague cases. The figures show the proportion of human cases averted over one season (July 1 to June 30) as a function of the month of intervention when (A) only rats are targeted, (B) only fleas are targeted, and (C) both rats and the fleas on those rats are simultaneously targeted. Reduction levels are represented by gray dots (20% population reduction), red triangles (50% population reduction), and yellow rectangles (80% population reduction). Vertical bars indicate the 95% credible intervals.

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Reposted by Fanohinjanaharinirina Rasoamalala

Antoine Brault @abrault.bsky.social · 13/06/2025

Plague remains a health issue in several parts of the world—especially in Madagascar, where epidemics follow a seasonal pattern. In our new @pnas.org paper, we link that seasonality to rat and flea dynamics and quantify the impact of various control strategies. doi.org/10.1073/pnas...

doi.org

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

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