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EUROSERPIN

@euroserpin.bsky.social
26 followers 40 following 2 posts

A network of biomedical researchers with an interest in the biology of serpins, their protease and ligand targets, and the pathways they regulate.

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EUROSERPIN @euroserpin.bsky.social · 04/06/2025
The EUROSERPIN2025 meeting, held at the Cloister of San Faustino, University of Brescia, has just ended. Thanks to all participants, speakers, poster presenters and to the University of Brescia. We can't wait for the next EUROSERPIN meeting!
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Vienna BioCenter Scientific Training @vbcscitraining.bsky.social · 26/03/2025
We're welcoming a new cohort of PhD students to the Vienna BioCenter PhD program from various universities around the world. Our Spring call with 25+ fully-funded PhD positions in the life sciences is now open: vbcphd.at @viennabiocenter.bsky.social @vbcscitraining.bsky.social
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bioRxivpreprint @biorxivpreprint.bsky.social · 10/01/2025
Tandem duplication of serpin genes yields functional variation and snake venom inhibitors. www.biorxiv.org/content/10.1101/202…
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Matt Bogyo @mbogyo.bsky.social · 16/01/2025
Excited to report our studies that identified a new serine protease secreted by the gut microbe Bacteroides fragilis that regulates pain and inflammation through PAR2 activation. #ChemBio. Check it out!https://www.biorxiv.org/content/10.1101/2025.01.15.633241v1
biorxiv.org
Identification of a secreted protease from Bacteroides fragilis that induces intestinal pain and inflammation by cleavage of PAR2
Protease-activated receptor 2 (PAR2) is a central regulator of intestinal barrier function, inflammation and pain. Upregulated intestinal proteolysis and PAR2-signaling are implicated in inflammatory ...
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EMBL-EBI @ebi.embl.org · 28/01/2025
Rare disease research relies on collecting genomic and clinical data across multiple countries. Learn more about the Solve-RD project and how it aims to collect and harmonise #raredisease data across multiple European partners. 🧬🖥️ www.ebi.ac.uk/about/news/a...
ebi.ac.uk
Solve-RD: supporting rare disease data collection and harmonisation
The Solve-RD project standardises genomic and clinical data across Europe to support rare disease research.
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EUROSERPIN @euroserpin.bsky.social · 29/01/2025
We are pleased to announce #EUROSERPIN2025, to be held in Brescia, Italy on May 28-30th 2025! This meeting will bring together international researchers to share their work on all aspects of serpin-related topics. Visit euroserpin.eu to register and submit an abstract.
EUROSERPIN2025 BRESCIA 28-30 MAY 2025. Flyer showing Piazza della Loggia, Brescia.
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Joe Chambers @joechambers.bsky.social · 13/11/2024
A bit of microscopy to get me off the mark! Single particle tracking of fluorescent, 20nm spherical protein assemblies (GEMs) as they dance through the ER-lumen of a COS7 cell. One of the tools we used to assess ER-biophysics in α1-antitrypsin deficiency science.org/doi/10.1126/sciadv.abm2094
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Rob Waterhouse @rmwaterhouse.bsky.social · 28/01/2017
#Anopheles gambiae SRPN18 crystal structure non-inhibitory serpin @Michel_Lab @IUCr scripts.iucr.org/cgi-bin/paper?S205…
scripts.iucr.org
1.45 Å resolution structure of SRPN18 from the malaria ve...
The structure of the A. gambiae serine proteinase inhibit...
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Structural Biology Communications @actacrystf.iucr.org · 11/11/2024
Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization t.co/ilB7Aa3Krg
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