Excited to share that part of my dissertation research was recently published! This paper explores how the PD-associated D620N variant in VPS35 affects retromer protein interactions in the brain. Grateful to my mentor (@moorelabvai.bsky.social) & my co-authors!
www.sciencedirect.com/science/arti...
sciencedirect.com
Parkinson's disease-linked D620N mutation selectively alters the brain-specific protein interactome of VPS35
Mutations in several genes are known to cause familial forms of Parkinson's disease (PD), including mutations in the vacuolar protein sorting 35 ortho…
