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Hideaki E. Kato

@emekato.bsky.social

Professor at UTokyo. (postdoc @Stanford) / b.1986 / structural biology, protein engineering, rhodopsin, GPCRs tinyurl.com/ycyf87t7

Posts Replies Media

Hideaki E. Kato @emekato.bsky.social · 08/04/2026

www.biorxiv.org/content/10.6... New preprint from our lab! Solving antagonist-bound GPCR structures is becoming easier with fusion markers, but linker optimization between GPCR and marker is still a bottleneck. (1/2)

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Hideaki E. Kato @emekato.bsky.social · 11/03/2026

Happy to share our work on conventional and time-resolved cryo-EM studies of NTSR1, now published in Nature! nature.com/articles/s41... Wonderful collab. w/ Sumino, Mitsutake, Kobilka, & Inoue labs. Congrats to Kazuhiro, Kouki, Toshiki, Shun & everyone involved!

nature.com

The dynamic basis of G-protein recognition and activation by a GPCR - Nature

Conventional and time-resolved cryo-electron microscopy reveal how NTSR1 dynamically engages and releases different G proteins, capturing over 20 intermediates and uncovering key mechanistic step...

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Hideaki E. Kato @emekato.bsky.social · 18/09/2025

Happy to share our new preprint on the red-shifted channelrhodopsin ChR024, recently discovered by Inoue Lab (biorxiv.org/content/10.1... ), highlighting its long-wavelength absorption and ion conductance: biorxiv.org/content/10.1... Many thanks to our wonderful lab members and collaborators!

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Hideaki E. Kato @emekato.bsky.social · 26/03/2025

Happy to share our work on the ligand selectivity and allosteric regulation of FFA2 using a combination of cryo‑EM, MD simulations, and mol. pharmacology! It was a great collab. with Ishikita, Dror, and Inoue labs. Congrats to Mai, Kouki, Ryoji, and everyone involved! www.nature.com/articles/s41...

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Hideaki E. Kato @emekato.bsky.social · 23/11/2024

Just made my account in BlueSky...

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