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Best of #ELCC26
#gotistobart — novel pH-sensitive anti-CTLA-4 antibody that selectively depletes intratumoral Tregs — vs docetaxel in metastatic sqNSCLC after anti-PD-(L)1 + platinum:
→ Median OS: not reached vs 10 months
12mOS: 63vs30% (HR 0.46)
→ ORR: 20% vs 4.8%
→ Manageable safety profile
