Reposted by Ellie Kaplan
Happy Friday! New preprint to discuss, led by @ekaplan.bsky.social, entitled "Activity-based selection for enhanced base editor mutational scanning"
www.biorxiv.org/content/10.1...
A thread...
biorxiv.org
Activity-based selection for enhanced base editor mutational scanning
Base editing is a CRISPR-based technology that enables high-throughput, nucleotide-level functional interrogation of the genome, which is essential for understanding the genetic basis of human disease...