Comparative efficacy and safety of prophylactic agents for #migraine in children and adolescents.
Riboflavin, topiramate-vitaminD, and levetiracetam showed the most consistent frequency signal, but CINeMA found no comparison reached high or moderate certainty.
Open access: doi.org/10.1186/s101...
![Fig 1. Sagittal cryo-sections of the rat brain (schematic reworked from
[38]). The coloured dots on the sections represent the
immunohistochemical mapping of hormones and their receptors in the
volume spanning 0.5 to 1.5 mm from the midline of the brain. Our
group has earlier examined the distribution of hormones and their
receptors [38-40]. The present figure shows the migraine related
regions, CGRP, oxytocin, oestrogen, AVP and related receptors. OT:
Oxytocin, OTR: Oxytocin receptor, ERα: Estrogen receptor alpha, AVP:
Vasopressin, V1bR: Vasopressin receptor 1b.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ey3f7xvclb6h4fjo2kvlklxy/bafkreicawyx7kldt3cve274nde6kj5zx3zbcv4jo42fqmkarpuszav5s3e)
