iiinova — where your digital self keeps evolving

Zeming Lin @ebetica.bsky.social · 10/12/2024

I'll be at NeurIPS for the workshops if folks want to meet up!

Reposted by Zeming Lin

Frank Noe @franknoe.bsky.social · 06/12/2024

Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science. www.biorxiv.org/content/10.1...

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Zeming Lin @ebetica.bsky.social · 04/12/2024

Evolution is non-linear, the next step in the evolutionary lineage of the ESM series of models is a sequence only protein language model that sets a new state of the art in representation learning. Check it out! The 300M and 600M models are open weights, 300M available for commercial usage.

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Reposted by Zeming Lin

Martin Pacesa @martinpacesa.bsky.social · 30/11/2024

#CASP16 results are in! Template-based VFold seems to be lead method for nucleic acid structure prediction! AlphaFold2 and 3 still seem to be best methods for protein monomer and complex prediction.

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Reposted by Zeming Lin

Michael Tschannen @mtschannen.bsky.social · 02/12/2024

Have you ever wondered how to train an autoregressive generative transformer on text and raw pixels, without a pretrained visual tokenizer (e.g. VQ-VAE)? We have been pondering this during summer and developed a new model: JetFormer 🌊🤖 arxiv.org/abs/2411.19722 A thread 👇 1/

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Sander Dieleman @sedielem.bsky.social · 02/12/2024

Better VQ-VAEs with this one weird rotation trick! I missed this when it came out, but I love papers like this: a simple change to an already powerful technique, that significantly improves results without introducing complexity or hyperparameters.

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Reposted by Zeming Lin

Mathurin Massias @mathurinmassias.bsky.social · 27/11/2024

Anne Gagneux, Ségolène Martin, @quentinbertrand.bsky.social Remi Emonet and I wrote a tutorial blog post on flow matching: dl.heeere.com/conditional-... with lots of illustrations and intuition! We got this idea after their cool work on improving Plug and Play with FM: arxiv.org/abs/2410.02423

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Zeming Lin @ebetica.bsky.social · 27/11/2024

I think the #1 way you can tell apart AI images is when they don't seem to tell a story at all. A lot of these seem like psychedelic fractals rather than art with some kind of underlying theme.

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Reposted by Zeming Lin

Sai Prasanna @saiprasanna.in · 26/11/2024

Arxiv sharing reminder pdf ❌ abs ✅

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Ardem Patapoutian @ardemp.bskyverified.social · 22/11/2024

Hey folks! I got a tattoo of my beloved PIEZO ion channel on my arm! Now I can show how they activate (flatten) under pressure by flexing—Will add a bit of performance art to my science talks 🧪🧠.

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Reposted by Zeming Lin

Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 14/11/2024

Evo: A genomic language model of prokaryote genomes generates functional cas9 proteins and transposons. @brianhiestand.bsky.social www.science.org/doi/10.1126/...

Evo, a 7-billion-parameter genomic foundation model, learns biological complexity from individual nucleotides to whole genomes.

Pretraining a genomic foundation model across prokaryotic life.

Fine-tuning on CRISPR-Cas sequences enables generative design of protein-RNA complexes.

Fig. 4. Fine-tuning on IS200/IS605 sequences enables generative design of transposable biological systems.

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Reposted by Zeming Lin

Lucas Beyer (bl16) @giffmana.ai · 20/11/2024

www.astralcodexten.com/p/how-did-yo...

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Reposted by Zeming Lin

Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 21/11/2024

Two full starter packs for your bioml needs!

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Reposted by Zeming Lin

Anshul Kundaje @anshulkundaje.bsky.social · 20/11/2024

We're about to release a pretty massive multiome atlas (includes chromatin) of several adult tissues via ENCODE4 + a significant expansion of the bulk DNase and ATAC datasets (already out). Many more regions than ENCODE3.

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Zeming Lin @ebetica.bsky.social · 21/11/2024

What did it? The starter packs??

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Zeming Lin @ebetica.bsky.social · 18/11/2024

Hi Bluesky! I made it on Kevin's starter pack 😌😌😌 here to discuss all things bio and all things ML!

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Reposted by Zeming Lin

Sander Dieleman @sedielem.bsky.social · 15/11/2024

In a gratuitous attempt to acquire more followers myself 😁, I've made a start on a "starter pack". Hopefully as more people from 🐦 make it over to 🦋, we can extend this a bit. Suggestions welcome! I've noticed not all accounts seem to be eligible to be added, anyone know what's up with that? 🤔

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Reposted by Zeming Lin

Kevin K. Yang 楊凱筌 @kevinkaichuang.bsky.social · 18/11/2024

Two BioML starter packs now: Pack 1: go.bsky.app/2VWBcCd Pack 2: go.bsky.app/Bw84Hmc DM if you want to be included (or nominate people who should be!)

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