iiinova — where your digital self keeps evolving

Got to meet the puppies at #ACR25! They are here until 4 today.

041

Dr. Bas Vastert, Care Transformation in Childhood Arthritis via Precision Medicine: sJIA treatment ⭐️cytokine monitoring, especially IL-18 ⭐️T2T with biologic first approach in Netherlands- most patients don’t receive any GCs #ACR25 #ACRambassador

022

Dr. Bas Vastert, Care Transformation in Childhood Arthritis via Precision Medicine: Window of opportunity ⭐️in non-systemic #JIA: ⬆️ inactive disease with earlier biologic start (<6mo) ⭐️in sJIA: integrating biomarkers in clinical care, early targeted tx #ACR25 #ACRambassador

142

Dr. Rae Yeung, Understanding and Harnessing the Biology of Arthritis 4. Naming is important because guides therapy #ACR25 #ACRambassador #kidsgetarthritistoo

Dr. Rae Yeung, Understanding and Harnessing the Biology of Arthritis 1. JIA classification has been a journey. Not every patient finds a home, & peds doesn’t consistently translate to adult classification. Is there a way to do this from a biologic basis? #ACR25 #ACRambassador

Looking forward to starting my day off in the Networking Lounges for the AMIGO event at 8:20 AM. Hope to see many fellow #pedsrheum there! #ACR25 #ACRambassador #pedsrheumsky

000

Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Social Media 🚨 opportunity for increased healthcare provider engagement #ACRambassador

Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Understanding Disease -ANA positive ITP patients have higher rates of SLE and Sjogren -Specific inborn errors of immunity are at increased risk of ANCA and AAV features #ACRambassador

Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Guidelines -EULAR/PReS Still’s Guidelines -French protocol for treatment of #JIA -ACR Guidance for Mental Health #ACRambassador

Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Medications -New FDA approvals: emapalumab, guselkumab -CAR-T cells in #JDM: a child with aggressive JDM achieved remission -Stem cell transplant: high morbidity, those who survive do well #ACRambassador

122

Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Deprescribing -a large number of patients JIA flare off therapy -lower uveitis recurrence with slower ADA tapering schedule #ACRambassador

121

Dr. Nigrovic presents #pedsrheum Basic & Translational Year in Review at #ACR25: 1. JIA 2. MAS 3. JDM 4. SLE 5. Monogenic diseases

Calling all #pedsrheum researchers at #ACR25! Hope you can attend this evening's networking event from 4-5 PM. This event is particularly geared for early career investigators and fellows in training. #pedsrheumsky

Drs. Linda Hiraki and Bonnie Bermas discuss applying 2025 SLE Guidelines to #cSLE ⭐️Peds specific GC dosing: GCs impact physical appearance ➡️ self-identity, mood ⭐️ Mental health screening is 🔑 ⭐️Impact on growth ⭐️Monitor school attendance/performance ⭐️Transition #ACR25 #ACRambassador #pedsrheumsky

022

The 2025 ACR extrarenal SLE guideline includes 36 graded recommendations 🔑HCQ= standard therapy 🔑GCs to control initial inflammation/flare; taper ASAP 🔑Early use of immunosuppressive therapies 🔑Shared decision making #ACR25 #ACRambassador

032

#ACR25 Clinical Year in Review by Dr. Bryant England (2/2): #Lupus ⭐️ 2024 lupus nephritis guidelines recommend triple therapy ⭐️ New option for 3rd therapy to treat lupus nephritis: obinutuzumab #ACRambassador

021

#ACR25 Clinical Year in Review by Dr. Bryant England (1/2): #Sjogren ⭐️ “The name has caught up to the science in Sjogren’s.” ⭐️ Potential role for salivary autoantibodies #ACRambassador

121

#ACR25 Basic Science Year in Review by Dr. Anne Davidson (3/3): Emerging conference themes ⭐️ CAR-T: upcoming sessions for #rheumsky and #pedsrheumsky ⭐️AI: resource provided for those interested in learning more #ACRambassador

#ACR25 Basic Science Year in Review by Dr. Anne Davidson (2/3): Take home messages about the progression of RA from preclinical to clinical state #ACRambassador

#ACR25 Basic Science Year in Review by Dr. Anne Davidson (1/3): 🔑 papers from the past 12 months #ACRambassador

Cutting it close to making the #ACR25 Year in Review. Of course today is the day Sapling decides to sleep in.

131