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Lucy MacDonald

@drlucymac.bsky.social
151 followers 86 following 4 posts

Research Associate at School of Infection and Immunity, University of Glasgow 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Mapping macrophage & DC niches with single cell spatial transcriptomics 🔬🧭

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Lucy MacDonald @drlucymac.bsky.social · 29/11/2024
The proudest supervisor ever!! No surprise our Jack is a superstar 🌟🌟🌟
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Lucy MacDonald @drlucymac.bsky.social · 27/11/2024
Thank you Julia!
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Lucy MacDonald @drlucymac.bsky.social · 27/11/2024
Highlights • Tolerogenic AXL+ DC2s reside beneath the healthy synovial lining • iDC3s populate RA hyperplastic lining, activating CCL5 Tem and/or Tph cells • CCR7+ DC2s in sublining lymphoid niches in RA, interacting with naive T cells • blood DC3s signature predicts RA flare
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Lucy MacDonald @drlucymac.bsky.social · 27/11/2024
So happy to (finally!!) announce that our paper studying synovial tissue dendritic cells in joint health and rheumatoid arthritis is now out in Immunity! 🚨 doi.org/10.1016/j.im...
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