drjosull.bsky.social @drjosull.bsky.social · 08/01/2025#Malnutrition #Neurodevelopment #GutMicrobiome #GlobalHealth #DataScience #MachineLearning #NutritionResearch #ChildHealth #LigginsInstitute #icddrb 000
drjosull.bsky.social @drjosull.bsky.social · 08/01/2025Thanks to Theo Portlock, Talat Shama, Shahira Kakon, Berit Hartjen, Chris Pook and Brook Wilson for their skills in generating and analyzing the data and writing the manuscript. 100
drjosull.bsky.social @drjosull.bsky.social · 08/01/2025Huge thanks to the families in Mirpur, Dhaka & our collaborators at icddr,b, Boston Children’s Hospital, Liggins Institute, & UWI. This is part of the #M4EFaD study, supported by @WellcomeLeap & the governments of Bangladesh & Canada. Let’s improve interventions for children! 100
drjosull.bsky.social @drjosull.bsky.social · 08/01/2025Our findings support the hypothesis that prolonged colonization by oral commensal species delay gut microbiome and brain development. While causal links require validation, this study provides insights to improve interventions targeting MAM-associated neurodevelopmental deficits. 100
drjosull.bsky.social @drjosull.bsky.social · 08/01/2025Oral commensals (Rothia mucilaginosa, Streptococcus salivarius) increased, while Bacteroides fragilis decreased—tied to lower odd-chain fatty acids, reduced beta/gamma EEG power, & fewer vocalizations. This points to delayed gut & brain development. 100
drjosull.bsky.social @drjosull.bsky.social · 08/01/2025Excited to share new research on how Moderate Acute Malnutrition (MAM) shapes the microbiome & neurocognitive development in children from Dhaka, Bangladesh. Using random forest & network analysis, we found key microbial & brain activity changes. doi.org/10.1038/s414... 141
