iiinova — where your digital self keeps evolving

Reposted by Drice Challal

Jonathan Jagodnik @jagodnikscience.bsky.social · 06/04/2025

I am thrilled to share this new preprint from our lab! We find (>800!) 30S binding sites in hundreds of 5'UTRs, but also new dynamic steps of translation initiation. www.biorxiv.org/content/10.1... Congrats to all co-authors at the RNA control of gene expression lab, IBPC CNRS (Thread, 1/6)

biorxiv.org

30S-seq redefines the bacterial Ribosome Binding Site

The translation initiation step is rate limiting for the efficiency of gene expression in all organisms. However, the mechanism of ribosome recruitment to mRNA start sites strikingly differs between e...

24826

Drice Challal @dricechallal.bsky.social · 05/04/2025

Thrilled to see our story now out at @naturecomms.bsky.social A shared adventure with Estelle Leroy and Mathieu Rougemaille @i2bcparissaclay.bsky.social, and with the precious help of the @palancadelab.bsky.social Such a tiny RNA with such a wide range of functions www.nature.com/articles/s41...

4138

Reposted by Drice Challal

Maxence Lejars @mlejars.bsky.social · 21/03/2025

Happy to share our genetic toolkit designed to make your gene editing (life) easier, faster and very efficient! Also suitable to build saturated chromosomal variant libraries using oligo-recombineering with extra short homology arms! www.biorxiv.org/content/10.1...

03923

Drice Challal @dricechallal.bsky.social · 30/03/2023

Merci beaucoup for your precious contribution to this work ! @I2BCParisSaclay x.com/ASadylab/statu…

000

Drice Challal @dricechallal.bsky.social · 22/12/2018

My main Ph.D project on the role of General Regulatory Factors in protecting promoters from ectopic and divergent transcription initiation is now available. So enthusiastic to finally see the result of this great adventure with @DomenicoLibri @LabLibri @MolecularCell x.com/MolecularCell/…

000