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Virgile Adam

@drfluo.bsky.social
228 followers 504 following 131 posts

#CNRS #researcher (PhD/HDR) working on : #FluorescentProteins 🧬; #MolecularBiology 👨‍🔬; #SMLM 🔬; #Crystallography 💎; #Biochemistry 🧪..

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Virgile Adam @drfluo.bsky.social · 29/08/2025
Saddened to learn of the passing of Prof. Michel Robert-Nicoud, Emeritus, and one of my former university teachers, with whom we often discussed what he called F-techniques: all the fluorescence-based techniques used to measure intracellular metrics. He accepted being the chairman of my PhD defense
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Virgile Adam @drfluo.bsky.social · 17/07/2025
New paper about the slow maturation of the fluorescent protein mEos4b and how to improve it (onlinelibrary.wiley.com/doi/10.1002/...)
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Virgile Adam @drfluo.bsky.social · 01/06/2025
New paper about a python software to process spectra within protein crystals (journals.iucr.org/j/issues/202...)
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Virgile Adam @drfluo.bsky.social · 18/04/2025
Sometimes I forget why I always loved so much studying FPs, and sometimes I remember!
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Virgile Adam @drfluo.bsky.social · 07/01/2025
Sine and I, 20 years ago at the ESRF
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Virgile Adam @drfluo.bsky.social · 06/01/2025
Deeply saddened by the announcement of Prof Sine Larsen's passing. Former scientific director of the European Synchrotron Radiation Facility and president of the International Union of Crystallography, Sine had been Emeritus at the University of Copenhagen for several years.
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Virgile Adam @drfluo.bsky.social · 02/09/2024
A last thank you to everyone for this great #SMLMS2024 event that was the opportunity to hear, meet or recontact with great people and discover beautiful places.
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Virgile Adam @drfluo.bsky.social · 30/08/2024
Impressive and colorful work by @christlet presented at the #SMLMS2024 about axonal organization with incredible STORM/Platinum replica EM correlations
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Virgile Adam @drfluo.bsky.social · 30/08/2024
A very good question asked by @l_masu at #SMLMS2024. The answer is the super duper resolution (© @rita_strack) allowed by RESI.
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Virgile Adam @drfluo.bsky.social · 30/08/2024
Interesting talk about cell phototoxicity metrics with "PhotoFiTT" by @_mariod at the #SMLMS2024, which makes you want to try it
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Virgile Adam @drfluo.bsky.social · 30/08/2024
Great great talk by @Melike_Lak about super-resolution for biology at #SMLMS2024. Chromatin compaction and dynamics metrics & chromatin remodelling depending on the stiffness of the cells environment and visualized/measured thanks to SR... fascinating!
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Ok, I'm impressed #SMLMS2024
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Virgile Adam @drfluo.bsky.social · 29/08/2024
More than full auditorium for the amazing talk of @rita_strack at the #SMLMS2024. That really great gives hints to know whether or not (and how) daring submitting to Nature Methods :
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Virgile Adam @drfluo.bsky.social · 29/08/2024
For those interested in X-rays and neutrons for chemistry, physics and biology, the #HERCULES2025 European school will be held in Grenoble, France in March/April 2025. Deadline October 2024.
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Virgile Adam @drfluo.bsky.social · 29/08/2024
SPAD-array detector for MINFLUX. Very interesting discoveries (and keywords) for a not-so-much optics guy like me, by @EliSlenders at the #SMLMS2024
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Focal adhesion complexes and DNA-PAINT... great work by @RomanTsukanov at #SMLMS2024
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Thrilled to come back at the #SMLMS2024 after a long pause. Last time for me was in 2015. What an evolution since the first I went to 12 years ago! We could then all fit in a classroom and have a personal talk by Prof W.E. Moerner (before his Nobel Prize). Congratulations and…
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Great talk about peptidoglycan dynamics in Staph by @PinhoLab at thee #SMLMS2024 yesterday!
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Beautiful presentation (as usual) about bacteria by @UEndesfelder in a talk chaired by @rita_strack at the #SMLMS2024 yesterday!
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Virgile Adam @drfluo.bsky.social · 29/08/2024
SMLMS methods and techniques are important but fluorophores development also. Thanks for all the nice chats and contacts at the poster session of the #SMLMS2024 yesterday. Would you be interested in smart fluorescent proteins' engineering, here I am ;
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Such a nice presentation at the #SMLMS2024 Lisbon by @JonasRies! Super resolution microscopy for structural biology, obviously ring many bells for me. Hope that our latest FPs in test for #minflux will work and lead to collaboration.
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Beautiful presentation (as usual) about bacteria by @UEndesfelder in a talk chaired by @rita_strack at the @SMLM_Symposium yesterday!
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Great talk about peptidoglycan dynamics in Staph by @PinhoLab at thee @SMLM_Symposium yesterday!
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Virgile Adam @drfluo.bsky.social · 29/08/2024
Wonderful presentation about deeplearning-assisted bacterial imaging (DeepBac) by @miCHRIScopy yesterday at the @SMLM_Symposium Lisbon.
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Virgile Adam @drfluo.bsky.social · 26/03/2024
Done. That was (normally) the very last diploma of my life. Thanks again @Marie_Erard75, @PedelacqJD, @EmmanuelMargeat, Eve de Rosny and Antoine Delon! Next target: director of research. My application was retained for an audition in a couple of weeks 😱
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Virgile Adam @drfluo.bsky.social · 29/12/2023
New paper about the heterogeneity of states in the green form of the photoconvertible fluorescent protein mEos4b. onlinelibrary.wiley.com/doi/10.1002/ad…
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Virgile Adam @drfluo.bsky.social · 21/09/2023
ibs.fr/IMG/pdf/lettre…
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Virgile Adam @drfluo.bsky.social · 21/09/2023
virgile-adam.com/_files/ugd/d0e…
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Virgile Adam @drfluo.bsky.social · 17/08/2023
For once I could try the 13-tubes equilibration ;
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Virgile Adam @drfluo.bsky.social · 02/08/2023
I got a skeptical crystallization drop 🤷‍♂️
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Virgile Adam @drfluo.bsky.social · 30/06/2023
New paper about the photophysics of fluorescent proteins at cryogenic temperatures. pubs.acs.org/doi/10.1021/ja…
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Virgile Adam @drfluo.bsky.social · 26/04/2023
2 PhD positions in biophysics at the Institute of Structural Biology IBS Grenoble, France Mechanistic investigations of photoswitchable fluorescent proteins by NMR, X-ray crystallography and single-molecule imaging.
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Virgile Adam @drfluo.bsky.social · 25/11/2022
Impressive perspective of the mass that we represent among living things (in gigatons of carbon): 0.23% of animals which themselves represent only 0.47% of the mass of all life. The human being therefore represents only 0.01% of the biomass on our planet.
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Virgile Adam @drfluo.bsky.social · 22/11/2022
Shake that fiber!
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Virgile Adam @drfluo.bsky.social · 07/10/2022
First time I make an illustration for the cover of the journal in which hosts our latest paper. That was fun.
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Virgile Adam @drfluo.bsky.social · 12/08/2022
New paper in Chemphyschem about the rsEGFP2, a reversibly switchable fluorescent protein (RSFP) and some of its mutants that allow to structurally understand switching contrasts of RSFPs. …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cp…
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Virgile Adam @drfluo.bsky.social · 16/04/2022
New synchrotron data collections ongoing on fluorescent proteins Poke @NathanShaner @LABrechaun ... you should recognize this one that I'm still struggling on
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Virgile Adam @drfluo.bsky.social · 12/04/2022
Why am I so messy?
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Virgile Adam @drfluo.bsky.social · 07/12/2021
OK, I gave a try to this new trendy thing: wombo app. I tried titles of my articles without particular style applied and I must admit that it's both mesmerizing and impressive that an AI can give a good overview of my job topic with such surrealistic pictures.
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Virgile Adam @drfluo.bsky.social · 03/09/2021
Here we are... there's quite a lot of protein in here
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Virgile Adam @drfluo.bsky.social · 03/09/2021
Follow up. From a single colony to half a liter
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Virgile Adam @drfluo.bsky.social · 02/09/2021
More than 15 years studying fluorescent proteins and I still can't get enough of these bacterial colonies shining like constellations.
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Virgile Adam @drfluo.bsky.social · 30/06/2021
I received this request today, which could barely be farther away from my field of expertise... Digging a bit, I discovered this article. I now think of deleting this Academia account of mine aleksiaaltonen.medium.com/i-deleted-my-a…
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Virgile Adam @drfluo.bsky.social · 11/05/2021
Star ?⭐, Flower ? 🌺... Nope. Those are some of my new fluorescent protein crystals
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Virgile Adam @drfluo.bsky.social · 26/01/2021
A 3-year postdoc position is available in our group at the IBS, Grenoble for Invastigation structural dynamics green-to-red photoconvertible fluorescent proteins for the design of ultrastable variants
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Virgile Adam @drfluo.bsky.social · 18/12/2020
When you realize, making a cloning for CRISPR-Cas9, that you're too confident and deposited without backup all your plamid on your gel so that if you lose it, you lose all. *Phew of relief* 😅 I wouldn't have doubted of me like that before. Good or bad sign... I don't know
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Virgile Adam @drfluo.bsky.social · 29/10/2020
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Virgile Adam @drfluo.bsky.social · 29/10/2020
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Virgile Adam @drfluo.bsky.social · 16/10/2020
So far so good... From gene cloning to bacteria to f***ing bright protein. Next steps: crystals and structure. #FluorescentFriday
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Virgile Adam @drfluo.bsky.social · 08/10/2020
So happy that they invented this pocket in blue jeans whose sole purpose is obviously to thaw frozen tubes! 😆
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