dpostrach.bsky.social @dpostrach.bsky.social · 11/01/2025The best way to spark interest in science is by sharing the beauty of microscopy images. I'm excited to see my picture of the intestine featured in the Dutch newspaper 'de Volkskrant'! #microscopy #ScienceArt 030
dpostrach.bsky.social @dpostrach.bsky.social · 10/01/2025Our preprint of Polytope is featured in the ISEH preprint watch 060
dpostrach.bsky.social @dpostrach.bsky.social · 03/12/2024Excited to share our preprint: Polytope, an epitope barcoding system, generating up to 512 unique color codes for in vivo lineage tracing. 🌈🧬 This tech enables spatial fate-mapping with unprecedented clonal and spatial resolution! doi.org/10.1101/2024... #SpatialBiology #LineageTracing #Polytopedoi.orgPolytope: High-resolution epitope barcoding for in vivo spatial fate-mappingTracing the fate of individual cells and their progeny remains a challenging task. While imaging-based fate-mapping provides spatial information, it generally lacks complexity due to limited label div... 0155
Reposted by @dpostrach.bsky.socialLarissa Frank @larissafrank.bsky.social · 01/12/2024🎉 Next preprint on its way! #Polylox #barcoding + computational modelling meets #macrophage #development! We used 𝐮𝐧𝐛𝐢𝐚𝐬𝐞𝐝 𝐏𝐨𝐥𝐲𝐥𝐨𝐱 𝐛𝐚𝐫𝐜𝐨𝐝𝐢𝐧𝐠 to trace thousands of embryonic progenitor clones and map their development into tissue-specific macrophages. Happy reading! doi.org/10.1101/2024...doi.orgHolistic genetic barcoding reveals a lineage tree of tissue macrophage developmentTissue macrophages are crucial for organ development and homeostasis, yet the developmental routes leading to tissue macrophages remain controversial. By combining unbiased Polylox barcoding with comp... 182
Reposted by @dpostrach.bsky.socialbioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 30/11/2024Holistic genetic barcoding reveals a lineage tree of tissue macrophage development www.biorxiv.org/content/10.1101/202… biorxiv.orgHolistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1 Tissue macrophages are crucial for organ development and homeostasis, yet the developmental routes l 166
Reposted by @dpostrach.bsky.socialbioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 22/11/2024Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping www.biorxiv.org/content/10.1101/202… biorxiv.orgPolytope: High-resolution epitope barcoding for in vivo spatial fate-mapping https://www.biorxiv.org/content/10.1101/2024.11.20.624484v1 Tracing the fate of individual cells and their progeny remains a challenging task. While imaging-bas 031