advanced.onlinelibrary.wiley.com
RUNX2 Phase Separation Mediates Long‐Range Regulation Between Osteoporosis‐Susceptibility Variant and XCR1 to Promote Osteoblast Differentiation
A GWAS intergenic SNP (rs4683184) acts as an enhancer, altering the binding affinity of the transcription factor RUNX2 and resulting in changes in XCR1 expression and osteoblast differentiation. RUNX....