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Silvio Ragozzino @docsilvio.bsky.social · 07/12/2025

➡️ They may be rapid biomarkers and potential antifungal targets to differentiate C. albicans candidemia. A further step toward molecular diagnosis in invasive fungal infections. Thanks to the team for their great work 👏

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Silvio Ragozzino @docsilvio.bsky.social · 07/12/2025

🧪 20 patients with candidemia (10 C. albicans, 10 non-albicans) and 22 controls without sepsis. 📊 RNA-seq and qPCR revealed marked overexpression of miR-125a and miR-99b only in C. albicans. 🧬 These miRNAs were associated with repression of immune and cell-cycle genes.

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Silvio Ragozzino @docsilvio.bsky.social · 07/12/2025

I’m delighted to share this work from the research group led by Dr. Miguel Marcos, derived from my doctoral thesis. 🔬 We studied miRNA and mRNA profiles in the blood of patients with candidemia caused by Candida albicans and other species. www.sciencedirect.com/science/arti...

sciencedirect.com

MicroRNA whole-blood profiling in hospitalized patients with candidemia identified miR-125a-5p and miR-99b-5p as potential biomarkers for Candida albicans bloodstream infection

Analyze miRNA and mRNA expression in patients with bloodstream infection (BSI) caused by Candida albicans (CA) and non-albicans Candida spp. (CNA).We …

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